Overview Of Radiation Therapy Flashcards

(54 cards)

1
Q

High level radiation is in

A

Megavoltage

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2
Q

It destroys the cell ability to divide or multiply

A

Law of bergonie and tribondeau

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3
Q

Damage to healthy cells are the reason for

A

Side effects of radiotherapy

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4
Q

Goal of Radiotherapy

A

Curative

Palliative

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5
Q

Curative

A

Cure from cancer

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6
Q

Palliative

A

Relieve symptoms

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7
Q

Curative is also called

A

Radical radiotherapy

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8
Q

Considered emergency cases in radiotherapy

A

Bone metastasis with spinal cord compression
Cases with profuse bleeding
Mass obstructing the lungs
Brain matastasis

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9
Q

Aim of radiotherapy

A

Deliver a PRECISE measured dose of radiation to a DEFINED tumor volume

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10
Q

Members of radiotherapy team

A

Radiation Oncologist
Medical Phycist/Dosimetrist
Radiotherapy Technologist

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11
Q

Sample of immobilization devices

A

Alpha Cradle

Thermoplastic mask

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12
Q

Two forms of radiotherapy

A
External Beam (Teletherapy)
Internal Beam (Brachytherapy)
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13
Q

Given to a careful defined area through a machine that directs the high energy rays from outside the body at the cancer and the normal tissues

A

External Radiation Therapy

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14
Q

Places the source of the inside the body, as close as possible to the cancer cells

A

Internal Radiation Theraphy

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15
Q

The radioactive substances used typically include

A

Radium
Cesium
Iodine
Phosphorus

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16
Q

2 types of external beam radiation

A

Photon beam

Proton beam

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17
Q

The dose prescribed by the Radiation Oncologist to be received by the patient that must be absorbed at the tumor site from the radiation beam

A

Dose of Radiation

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18
Q

Unit of absorbed dose

A

Gray (Gy)

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19
Q

Made under simulated condition will assure the delivery of the exact prescribed dose

A

Detailed measurement

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20
Q

Dose of Radiation determination

A

Size tumor
Extent tumor
Grade of tumor
Response to radiation

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21
Q

Largest amount of dose that can be accepted without the production of injurious symptoms

A

Tolerance Dose

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22
Q

Factors affecting tolerance dose

A

Dose per fraction/dose rate
Volume irradiated
Sensitivity of the tissues
Amount of recovery which can take place between fractions

23
Q

The dose that can be tolerated by normal tissue in the treatment zone varies with the total time over which the dose is given

A

Dose per fraction/dose rate

24
Q

Dose that could be given in a longer period of time is ____ than given over a short period

25
Alter the biological effect
Size of each fraction dose | Time interval between the fractions
26
The higher the fraction dose
The greater the late damage potential
27
The smaller the volume to be treated
The higher total dose which may be tolerated
28
The type of tissue treated, poor dietary of fluid intake or concomitant drug treatment, may affect the level of dose tolerated
Patient and Biological Factors
29
Good oxygenation increases the chance of radiation damage to cells
Oxygen effect
30
Large cell mass where there is no organized blood supply
Hypoxic
31
If the number of cells doubles within the time interval between two fractions, treatment may fail
Cell Doubling Time
32
The administration of a course of radiation treatment in a planned series of fractions of total dose
Fractionation
33
Fractionation is needed to
Allow recovery of normal cells while depleting the number of surviving tumor cells
34
Some patients (head and neck) are at survival disadvantage
If treatment duration is lengthened
35
Fractionation Regimes
Conventional fractionated courses Less than 5 fractions per week Reason for lowered fractionation regimes
36
Consist of once-daily doses given 5 days per week, recovery period at weekend
Conventional fractionated courses
37
Once, twice, or three times weekly treatments with higher dose of radiation
Less than 5 fractions per week
38
Fewer visits and less traveling time for patients Shortage of treatment machine Clinical indications
Reason for lowered fractionation regimes
39
Shortening the treatment course duration but giving a high number of small fractions
Hyperfractionation
40
Given to rumors with a fast cell-doubling time such as 5 days
Hyperfractionation
41
Three distinct region for target volume
Gross tumor volume Clinical target volume Planning target volume
42
Denotes the demonstrable tumor
Gross tumor volume
43
Denotes the GTV and subclinical disease
Clinical target volume
44
Denotes the CTV and includes margins for geometric/position uncertainties
Planning Target Volume
45
Volume of tissue enclosed by an isodose surface
Treated volume
46
Is always larger than the PTV and usually has a simpler shape
Treated volume
47
Volume of tissue that receives a dose considered significant in relation to tissue tolerance
Irradiated volume
48
Necessary to make the marks permanent for the basis of body alignment
Tattoo Process
49
Factors to consider for side effects
Total dose delivered Time over which the dose was delivered Volume irradiated
50
Side effects are generally limited to the
Region of the body being treated
51
A skin condition that is a common side effect of radiation Theraphy
Radiation Dermatitis
52
Radiation can affect the membranes of the mouth and GI Tract causing discomfort
Nutritional problems
53
Most common side effects of radiation therapy
Fatigue
54
The use of high level radiation to destroy cancer cells
Radiation Therapy