P2Y12 Inhibitors Flashcards

1
Q

Clopidogrel (g)

A

Plavix (b)

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2
Q

MOA

A

prodrug that irreversibly binds to P2Y12 receptors on platelets to prevent aggregation

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3
Q

common adverse effects

A

bleeding

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4
Q

rare adverse effects

A

TTP (mental status change, vision changes, one-sided weakness, purple spots on skin/mouth, yellow skin, diarrhea, fast heartbeat, fever, headache)

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5
Q

clinical pearls

A

some people have genetic variances that can decrease efficacy

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