Paediatric Seizures

Question 1

What are 6 causes of seizures in Paediatric patients?

Answer 1

1. Hypoglycaemia
2. Hypoxia
3. Head Trauma
4. ICH/Stroke
5. Electrolyte disturbance
6. Meningitis

Question 2

What are the Midazolam Doses for GCSE in paediatrics

Answer 2

Adolescent (12 - 15) - 5mg IM
Medium Child (5 - 11) - 2.5 - 5mg
Small Child (1 - 4) - 2.5mg
Large infant ( <12mnths) 1mg
Newborn (<24hours) - 0.5mg

Question 3

What is the management for paediatric seizures after 10 minutes?

Answer 3

Repeat original Midazolam dose

Question 4

What are the 10 steps of a GCSE Pathophysiology

Answer 4

1. Initiation of excessive neuronal firing
2. Failure of seizure self-termination
3. Prolonged excitation of glutamatergi pathways
4. GABAergic system dysfunction
5. NMDA receptors upregulated
6. Increased metabolic demand
7. Cerebral Hyoxia and lactic acidosis
8. Autonomic dysregulation
9. Neuronal injury and Cytotoxic Oedema
10. Systemic Complications and multi-organ dysfunction