Page 4 Flashcards

1
Q

The degradation product of hemoglobin in the reticuloendothelial
system.

A

Bilirubin

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2
Q

Hemoglobin breakdown components?

A

Iron, protein, protoporphyrin

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3
Q

What cell converts protoporphyrin into bilirubin?

A

ReticuloEndothelial cells

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4
Q

Biliburin is transported via?

A

Conjugation

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5
Q

Conjugated bilirubin passes from what to where before converting to urobilinogen?

A

Bile canaliculi, to duodenum

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6
Q

Bilirubin in urine means what?

A

Liver damage

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7
Q

Bilirubinuria can detect these diseases

A

Hepatitis
Cirrhosis

Gallbladder Dse

Cancer

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8
Q

Reaction for bilirubin test?

A

Diazo reaction
Oxidation test

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9
Q

Reagent strip reagents for bilirubin?

A

2,4-dichloroaniline diazonium salt
OR
2,6-dichlorobenzene diazonium

+
2,4-dichloroaniline diazonium salt
OR
2,6-dichlorobenzene diazonium-tetraflouborate

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10
Q

Bilirubin reagent strip color range

A

Tan/Pink to Violet

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11
Q

Bilirubin confirmatory test/verification test if questionable

A

Ictotest

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12
Q

Ictotest Reaction

A

Diazo reaction

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13
Q

Ictotest form and reagents

A

Tablet form
: p-toluenesulfonate
: sulfosalicylic acid
: sodium carbonate
: boric acid.

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14
Q

Ictotest color reaction?

A

Blue to purple

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15
Q

Oxidation reagent composition

A

FeCl in TCA/Fouchet’s reagent

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16
Q

Oxidation color reaction?

A

Green

17
Q

Why oxidation of bilirubin is green?

A

Bilirubin becomes biliverdin