Page 4 (Nephrotic Syn, Lipid Nephrosis)

Question 1

There is increase permeability of the glomerular membrane due to disruption in the electrical charges in the basal lamina and podocytes, producing a less tightly connected barrier that allows massive loss of protein and lipids.

Answer 1

Nephrotic Syndrome

Question 2

Characterized by the presence of RTE cells, RTE cell casts, & fatty casts.

Answer 2

Nephrotic Syndrome

Question 3

Marked massive proteinuria (> 3.5 g/d)

Answer 3

Nephrotic Syndrome

Question 4

Low level of albumin

Answer 4

Nephrotic Syndrome

Question 5

Nephrotic Syndrome findings

Answer 5

Hematuria (Microscopic)
Proteinuria (Heavy)

Fatty Cast
Waxy Cast

Fat droplets
Oval Fat bodies

RT cells

Question 6

Nephrotic Syndrome significant tests

Answer 6

Serum albumin
Cholesterol
Triglycerides

Question 7

Podocytes appear to be less tightly fitting allowing increase infiltration of protein.

Answer 7

Lipid Nephrosis

Question 8

Seen in children following allergic reaction and immunization.

Answer 8

Lipid Nephrosis

Question 9

Lipid Nephrosis findings

Answer 9

Hematuria (Transient)
Proteinuria (Heavy)

Fat Droplets

Question 10

Lipid Nephrosis significant test

Answer 10

Serum albumin
Cholesterol
Triglycerides