Pain Flashcards

(55 cards)

1
Q

Definition of primary pain

A

No obvious cause or pain is out of proportion to any obvious injury/disease

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2
Q

Definition of secondary pain

A

Caused by an underlying condition

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3
Q

How often should pain relief for chronic pain be reviewed?

A

At least annually

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4
Q

Definition of chronic pain

A

pain >12 weeks

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5
Q

Why are fixed dose combination products containing low-dose opioids not used in chronic pain?

A

Increase side effect burden without offering additional pain relief

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6
Q

Describe the licensing for opioid use in pain

A

To be used short-medium term for when other therapies have been insufficient in chronic non-malignant pain

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7
Q

What is the paracetamol dosing in a 6-7 year old child?

A

240- 250mg every 4-6 hours. Max 4 doses in 24 hours

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8
Q

What is the paracetamol dosing in a neonate 28-32 weeks corrected gestational age?

A

20mg/kg for 1 dose. Then 10-15mg/kg every 8-12 hours. Max 30mg/kg in 24 hours

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9
Q

What is the paracetamol dosing in a neonate 32+ weeks corrected gestational age?

A

20mg/kg for 1 dose. Then 10-15mg/kg every 6-8 hours. Max 60mg/kg in 24 hours

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10
Q

What is the paracetamol dosing in a child aged 1-2 months?

A

30-60mg every 8 hours. Max 60mg/kg in 24 hours

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11
Q

What is the paracetamol dosing in a child aged 3-5 months?

A

60mg every 4-6 hours. Maximum 4 times daily

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12
Q

What dose of opioids (morphine equivalent) requires a specialist pain referral?

A

> 90mg OD

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13
Q

Which NSAID has the weakest anti-inflammatory properties?

A

Ibuprofen

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14
Q

Which NSAIDs are associated with a particularly increased thrombotic risk?

A

High dose ibuprofen and diclofenac, selective COX-2 inhibitors

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15
Q

Which NSAID is licensed for pain associated with acute gout?

A

Etorcoxib

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16
Q

Which NSAID has the highest risk of GI side effects?

A

Piroxicam

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17
Q

What is Celecoxib licensed for?

A

Licensed for rheumatoid arthritis, ankylosing spondylitis and osteoarthritis

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18
Q

Which of the NSAIDs is superior to that of Naproxen but has a high SE profile including GI disturbances, dizziness and headaches?

A

Indomethacin

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19
Q

Which class of NSAIDs have a higher risk of GI side effects?

A

Non-selective COX-2 inhibitors

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20
Q

Which NSAID is associated with diarrhoea and haemolytic anaemia?

A

Mefenamic acid

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21
Q

Which NSAID is associated with a lower thrombotic risk than others?

A

Naproxen

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22
Q

From what point of pregnancy is it advised NSAIDs aren’t used?

A

Should be avoided from 20 weeks

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23
Q

Which trimester are NSAIDs completely contra-indicated in?

A

3rd trimester (week 28)

24
Q

What is a fundoscopy?

A

Investigation that looks at the optic nerve and retina (back of eye)

25
What does the SNOOP mnemonic stand for?
S- systemic signs and disorders N- neurological symptoms O- onset new or changed or onset >50 years old O- Onset in thunderclap presentation P- Pappiloedema, pulsative tinnitus, positional provocation, precipitated by exercise
26
What are the symptoms of an aura associated with migraine?
Visual symptoms, sensory symptoms e.g., pins and needles + numbness, dysphasia
27
Chronic migraine definition
Occurs on >15 days of the month, with 8 of those days demonstrating migraine characteristics + lasts >3 months.
28
Episodic migraine definition
episodes occur <15 days a month
29
Why are migraines more common in females?
Can correlate with drop in ostrogen before period
30
Complication of migraine
Medication overuse headache
31
Symptoms of migraine
Unilateral, pulsating headache, severe enough to interupt daily activities
32
How long should a headache diary be kept for?
Minimum 8 weeks
33
When should a 5-HT1- receptor agonist be taken in migraines associated with aura?
At start of headache, not aura.
34
When is nasal zolmitriptan and s/c sumatriptan indicated?
severe migraines or those who present with early vomiting
35
How many days is migraine treatment restricted to a week?
2 days
36
Second-line for migraines
Paracetamol
37
Treatment for acute migraine if monotherapy fails
Naproxen + sumatriptan
38
Fourth line treatment option for migraines
Rimegepant
39
Which anti-emetics can be used for pain associated with migraine in addition to their use in nausea?
Metoclopramide and prochlorperazine
40
Which antiemetics are used in migraine?
Metoclopramide, prochlorperazine, and domperidone
41
1st line for prophylaxis of migraine
Propranolol
42
2nd line for prophylaxis of migraine
Topirimate
43
3rd line for prophylaxis of migraine
Amitriptyline
44
4th line for prophylaxis of migraine
Candesartan
45
What antiepileptic can be used in migraine prophylaxis?
Sodium valproate in >55 years old
46
Which type of headache may present as a worsening of headache in the morning?
Idiopathic intracranial hypertension
47
Which 5HT-1 agonist is preferred in prophylaxis of pre-mesntrual migraine syndromes?
Frovatriptan- Given 2 days before menstruation and stopped 3 days after starting menstruation
48
Which headache is most likely to present with autonomic symptoms such as blood shot eye, runny nose, watery eye?
Cluster headache
49
1st line therapy for cluster headaches?
S/C sumatriptan
50
2nd line therapy for cluster headaches?
nasal Sumatriptan/ Zolmitriptan
51
What additional treatment can be used other than 5-HT1 agonists in the treatment of cluster headaches?
100% O2
52
Which steroid can be used in prophylaxis of cluster headaches?
Prednisolone
53
1st line for cluster headache prophylaxis
Verapamil or lithium
54
Which headache disorder may present as pulsatile tinnitus?
Idiopathic intracranial hypertension
55
Which headache disorder may present as photosensitivity?
Subarrachnoid haemhorrage