Pain Flashcards
A-alpha 1a
- Myelinated
- muscle spindle
- change in length
- 12-20 mm
- 70-120 ms
A-alpha 1b
- myelinated
- GTO
- 12-20 mm
- 70-120 ms
A-beta
- myelinated
- skin
- soft touch, vibration, hair deflection
- 6-12 mm
- 30-75 ms
A-delta
- myelinated
- skin
- sharp pain, temp, pressure
- 1-6 mm
- 6-40 ms “fast pain”
C
- unmyelinated
- skin, soft tissue, periosteum
- ## dull and diffuse pain
Thalamus
- identifies and sorts pain info via STT
- relays sensory and motor signal to cortex
- “information processing”
3 Types of superficial sensory receptors
Mechano, thermo, nocio
Superficial Mechanoreceptors
- Meissner’s and Pacinian Corpuscles, ruffini endings
- Pressure, skin stretch, and touch
Superficial Thermoreceptors
- cold and hot receptors
- temp and temp change
superficial nocioceptors
- free nerve endings
- pain
deep proprioceptors
- GTO, muscle spindle, pacinian corpuscles, ruffini endings
- muscle length, joint position, joint end range
deep nocioreceptors
- free nerve endings
- pain
deep mechanoreceptors
- GTO, muscle spindles, pacinian corpuscles
- muscle change, ligamentous deformation
2 somatosensory pathways and functions
- Dorsal column-medial lemniscus (mechano and propriception)
- spinothalamic tract (thermo and nocio)
Order of Transmisison for Dorsal column/medial lemniscus
Peripheral receptor (mechano & proprio) -> dorsal root ganglion -> dorsal root -> dorsal white column -> medulla -> cross over midline at gracilis & cuneatus -> medial lemniscus -> pons -> cerebellum -> midbrain -> thalamus (3rd) -> somatosensory motor cortex
Paleothalamic and Neothalamic tract order
“slow pain” - peripheral sensory receptor -> laminae II & III (substantia gelatinosa, start of 2nd)) -> laminae I & II -> up lateral (pain & temp) -> medulla (medial lemniscus) -> pons -> cerebellum -> thalamus (3rd) -> somatosensory motor cortex
Substance P
- in synapse
- activate transmission of pain producing impulses of 2nd order neuron