Pain Management Flashcards

(41 cards)

1
Q

What are two types of pain?

A
  • Nociceptive

- Neuropathic

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2
Q

What is nociceptive pain?

A
  • Noxious stimulus (chemical, thermal, mechanical) of nociceptors releases neural chemicals that also stimulate other nociceptors
  • Transmits signal to spinal cord
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3
Q

Sharp localized pain =

A

Large diameter, sparsely myelinated

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4
Q

Dull, aching pain =

A

Small diameter, unmyelinated

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5
Q

Perception of pain =

A

Conscious experience of pain

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6
Q

Pain impulse is relayed through ___

A

Thalamus

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7
Q

___ transmit pain

A

Higher cortical structures

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8
Q

Modulation =

A
  • Inhibition of impulses via the brain stem (body’s natural response to pain so you can go and get help)
  • Release of endogenous opioids, serotonin, NE, GABA
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9
Q

What is neuropathic pain?

A
  • Sustained by abnormal processing of sensory input
  • Nerve damage, persistent stimulation, autonomic dysfunction
  • Burning, tingling, shocks, hyperalgesia, allodynia
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10
Q

Chronic pain

A

> 3 months OR past the time of normal tissue healing

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11
Q

PQRST for monitoring pain

A
P: palliative and provocative factors
Q: quality
R: radiation
S: severity
T: temporal relations
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12
Q

Addiction

A

Using the medication beyond what it’s intended for; negatively impacting their daily lives

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13
Q

Abuse

A

Use of the medication beyond its intended use

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14
Q

Tolerance

A

Not getting the same therapeutic effects at current dose

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15
Q

Dependence

A

Require the medication for regular activities of daily living/normal quality of life

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16
Q

Who is at risk for inadequate pain control?

A
  • Racial and ethnic minority groups
  • Women
  • Elderly
  • Persons with cognitive impairment
  • Cancer and at the end of life
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17
Q

What is the optimal length of opioid prescriptions for general surgery procedures?

18
Q

What is the optimal length of opioid prescriptions for women’s health procedures?

19
Q

What is the optimal length of opioid prescriptions for musculoskeletal procedures?

20
Q

What pain meds work on transduction?

A
  • NSAIDs
  • COX-2 inhibitors
  • Antihistamines
  • Topical local anesthetics
21
Q

What pain meds work on conduction?

A
  • Peripheral nerve block

- Local anesthetics

22
Q

What pain meds work on transmission?

A
  • Epidural block

- Local anesthetics

23
Q

What pain meds work on modulation?

A
  • Opioids
  • Clonidine
  • COX-2 inhibitors
24
Q

What pain meds work on perception?

A
  • Opioids
  • Acetaminophen
  • Clonidine
  • TCAs
  • Gabapentin
25
What pain meds work on CNS responses?
- Muscle relaxants - TCAs - Beta blockers
26
Opioid receptors are located throughout...
The brain, spinal cord, and GI tract
27
Four subtypes of opioid receptors
- Delta - Kappa - Mu - Nociceptive
28
Delta
- Brain and peripheral nerves | - Analgesia, antidepressant, dependence
29
Kappa
- Brain, spinal cord, periphery | - Analgesia, sedation, miosis, dysphoria, ADH inhibition
30
Mu
-Brain, spinal cord, periphery, intestine
31
What are 3 types of mu receptors?
- Mu1 - Mu2 - Mu3
32
Mu1
Analgesia, dependence
33
Mu2
Respiratory depression, euphoria, reduced GI motility, dependence
34
Mu3
Unknown
35
Nociceptive
- Brain, spinal cord | - Anxiety, depression, appetite, tolerance to mu agonists
36
NMDA receptor may reduce ___. Why?
Opioid effectiveness, d/t overstimulation by glutamate (neuropathic pain)
37
How to combat NMDA receptor/opioid effectiveness
Augment via GABA receptors and NMDA receptor antagonists
38
Agonist
binds to the receptor and causes its effect
39
Partial agonist
Not a full signal, weaker than an agonist
40
Agonist-antagonist
made as an attempt to reduce side effects of opioids
41
Antagonist
Reversal of opioids