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PSYC475 psychopharm > pain medications > Flashcards

pain medications Flashcards

(56 cards)

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1
Q

fentanyl

A
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2
Q

oxycodone

A
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3
Q

duloxetine

A
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4
Q

tramadol

A
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5
Q

The cell bodies of nociceptors are found in the

A

dorsal root ganglion of the spinal cord

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6
Q

Fentanyl is at least ______ times more potent that morphine.

A

80

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7
Q

Dull, diffuse pain signals are transmitted via __________ fibers.

A

C

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8
Q

Combining acetaminophen with alcohol is dangerous because it can result in:

A

hepotoxicity

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9
Q

Which of the following drugs is a good choice for “poor metabolizers” or patients with compromised liver function?

A

propoxyphene

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10
Q

Suboxone is the combination of buprenorphine and

A

naloxone

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11
Q

To which receptor does oxycodone bind the most?

A

mu opioid

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12
Q

Inhibition of COX-1 results in

A

upset stomach

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13
Q

Vicodin is a combination of hydrocodone and

A

acetomenophin

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14
Q

Which of the following nuclei is NOT a part of the descending pain modification system?

A

nucleus basalts

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15
Q

NSAIDs

A
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16
Q

aspirin

A
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17
Q

ibuprofen (drug class, trade names)

A

NSAIDs

advil, motrin

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18
Q

naprozen (drug class, trade names)

A

NSAIDs

Aleve, Naprosyn

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19
Q

what is one of the #1 causes of acute liver failure

A

tylenol AKA acetominophen

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20
Q

why don’t take tylenol for a hangover?

A

you still have alcohol in your system —-> liver damage

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21
Q

what is considered one of the most dangerous OTC drugs?

A

tylenol / acetominophen

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22
Q

pros of ibuprofen?

A

not found in breastmilk

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23
Q

pros of toradol

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A

concurrent administration can dec morphine requirement

24
Q

issues w indocin (indomethin)

Study These Flashcards
A

inc side effect liability

25
pros of sulindac (clinoril)
less GI upset than indomethin
26
pros of diclofenac (voltaren)
Several preparations: delayed release, topical, skin patch
27
pros of nabutmeone (relafen)
rec for long term tmt; less GI upset vs aspirin
28
cons of celecoxib (celebrex)
no cardioprotective effects; may actually inc risk
29
morphine SE?
Side Effects: respiratory depression, pupillary constriction, constipation, decreased sex drive/fertility problems, itching
30
codeine is metabolized to..... _____ can block this transformation
morphine ((but SSRIs can block this transformation))
31
hydrocodone is used for.... (2)
Mild-Moderate pain, cough suppression
32
Vicodin / norco is _______ mixed with ________
hydrocodone ; acetaminophin
33
what is one of the most frequently abused presctiption drugs in the US
hydrocodone
34
heroin is _____x the potency of morphine
3
35
heroin is ______ soluable
lipid
36
hydromorphone / oxymorphone trade name:
dilauded , numorphan
37
hydromorphone / oxymorphone is ____-____x potency of morphine
6-10x
38
what drugs might inhibit the effects of hydromorphone / oxymorphone? (2)
antihistamines & MAOIs
39
merperidine has greater _________ effects than morphine
euphoric
40
methadone has a half life of ______hours
24-36hrs
41
issues with levo-alpha acetylmaethadol?
inc risk of cardiac effects
42
pros of levo-alpha acetylmaethadol?
long half life (2.5 days) , Long duration of action allows for less frequent dosing
43
pros of propoxyphene? (2)
Effects do not depend on metabolism; good choice for “poor metabolizers”; Less GI upset Lower risk of dependence
44
fentanyl is _____-_____x as potent as morphine
80-500x
45
what is buprenorphine used for?
Opioid dependency (suppresses craving, decreased euphoria)
46
pros of buprenorphine
Txts opioid dependency without risk of abuse
47
how does tapentadol (nucynta) work?
Mu agonist + blocks NET
48
pro of pentazocine?
Low risk of dependence or respiratory depression
49
nalmefene (Revex) is similar to naloxone, but _______
lasts longer
50
naltrexone is used to ________
treat opioid / alcohol dependence
51
methlynaltrexone/alvimopan has _______ effects, because _________
only peripheral effects; Does not cross BBB
52
Ibuprofen is an especially good choice for
nursing mothers
53
The metabolism of codeine into morphine can be blocked by
SSRIs
54
Compared to morphine, heroin is
more lipid soluable
55
Dull, diffuse pain signals are transmitted via __________ fibers.
C
56
What is the primary indication for acetaminophen?
Analgesia and antipyresis

PSYC475 psychopharm (14 decks)

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