Pain & Opioids Flashcards

1
Q

opiate vs opioid

A

opiates found naturally in opium poppy (morphine)
opioids includes synthetics

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2
Q

which types of pain are opioids good for

A

acute pain
cancer / end of life pain
NOT CHRONIC

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3
Q

causes of cancer pain

A

the cancer itself
anti cancer tx
cancer related debility
concurrent disorder

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4
Q

5 principles of cancer pain managment

A

tx reversible causes
when starting painrelief:
- by mouth
- by ladder
- by clock
- titrated as needed

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5
Q

how common in bone pain

A

commonest type of cancer pain
1/3 pts with bone mets have pain

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6
Q

which type of medication / Ix can help bone mets pain

A

bisphosphonates, radiotherapy, surgery

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7
Q

weak opioids

A

tramadol
codeine

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8
Q

which type of Ix is most effective for bone mets pain

A

radiotherapy

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9
Q

describe who analgesic ladder

A

non opioid
weak opioid + non opioid
strong opioid + non opioid
(adjuvants throughout)

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10
Q

strong opioids

A

fentanil
morphine
oxycodone

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11
Q

who can’t have codeine

A

kids
renal impairment

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12
Q

how does codeine compare to morphine

A

10x less potent than morphine

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13
Q

what do co-codamol numbers mean

A

first number = codeine
second number = paracetamol

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14
Q

what is co-codamol max dose determined by

A

amount of paracetamol !!

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15
Q

how does tramadol compare to morphine

A

10x less potent than morphine

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16
Q

how do you prescribe morphine

A

in mg not mls

17
Q

what are modified release morphines names
and how are they given

A

zomorph or MST
(12hr BD prep)

18
Q

what is immediate release morphine name

A

oromorph / sevredol (tabs)

19
Q

how do you work out the PRN dose

A

24hr dose / 6

20
Q

SE of opioids

A

constipation - almost 100%
nausea - common on initiation
drowsiness - common but resolves
itch - v rare

21
Q

toxicity sx

A

visual hallucinations - rats / spiders
myoclonic jerks
pinpoint pupils
resp depression
sedation / confusion

22
Q

preferred parenteral analgesia

A

morphine subcut

23
Q

po vs subcut morphine conversion

A

subcut is 2x potent as po morphine

24
Q
A