pain proprioception Flashcards

1
Q

nociceptors are

A

detector portions of pain afferent nerves

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2
Q

TPRV-1 mediates

A

hot peppers
pain for moderate ehat
pain from acidic environments

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3
Q

nociceptor afferent nerves require

A

more stimulus energy

and are tonic receptors

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4
Q

a delta fiebrs

A

large diameter with myelination and rapid conduction velocity
fast or first pain
inhibition of C fibers

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5
Q

Adelta HTM fibers synapse on

A

secondary nerves

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6
Q

c fibers

A

small diameter and no myelination
slow conduction velocity
70% of all pain fibers

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7
Q

c fibers stimulated by

A

thermal, mechanical, chemical stimuli

ischemia

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8
Q

c fiber stimulation pain perception is

A

dull achy burning

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9
Q

primary hyperalgesia is

A

increased pain responses at the site of the trauma

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10
Q

hyperalgesia is enhanced by

A

inflammation

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11
Q

inflammatory chemicals induce

A

vasodilation

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12
Q

classic signs of inflammation

A

dolar, ruber, calor, tumor

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13
Q

secondary hyperalgesia

A

released transmitters diffuse for some distance and stimulate pain nerve endings from nearby areas uninvolved with trauma

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14
Q

2 receptors that glutamte stimulates

A

AMPA NMDA

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15
Q

in short duration, small area trauma, mainly ___ receptors are activated in ___ nerves

A

AMPA and secondary

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16
Q

AMPA receptors normally stimulated by

A

low concentration of glutamate during acute pain

17
Q

early LTP is initiated if

A

if pain felt for 30 min following initial stimulus

18
Q

late LTP initiated if

A

if pain persists for days or more

involves protein synthesis

19
Q

windup increases secondary nerve activating cascase that

A

induces early LPT

20
Q

allodynia

A

pain due to stimulus that doesnt normally provoke pain

21
Q

inhibiting what cells blocks chronic pain

A

A11 cells that secrete dopamine

22
Q

neuropathic pain characterized by appearance of

A

dysasthesias (abnormal sensations)

23
Q

CRPS I

A

reflex sympathetic distrophy

no obvious neural damage

24
Q

CRPS II

A

involves nerve injury

25
Q

within laminae of spinal cord

A

efferents go to laminae and release endorphins and enkephalins

26
Q

pruritis itch mediated by stimulation of

A

C fibers