Pancreas Flashcards
(79 cards)
What is the brightest T1 organ in the body
Pancreas
What is pancreatic parenchymal phase?
Late arterial (~40 seconds)
Maximal size of pancreatic duct in adults and elderly?
3 mm and 5 mm.
3 categories of pancreatic neoplasms
Solid epithelial (2). Cystic epithelial (4). Endocrine neoplasms (5)
Solid epithelial neoplasms of pancreas (2)
Ductal adenocarcinoma (most common). Acinar cell carcinoma (rare, aggressive, can cause fat necrosis)
Cystic epithelial neoplasms of pancreas(4)
Serous cystic, mucinous cystic (PMCN), Solid Papillary Epithelial neoplasm (SPEN), Intraductal paillary neoplasm (IPMN)
Endocrine neoplasms of pancreas (5) + nonfunctioning Islet cell
Insulinoma, gastrinoma, glucagonoma, VIPoma, Somatostatinoma
Ductal Adenocarcinoma of pancreas: Demographics, risk factors
Age>60. Slightly more in males. Smoking, alcohol, pancreatitis.
Ductal Adenocarcinoma of pancreas: imaging (CT phase, T1, enhancement.
Panc head. Late arterial phase hypoenhancing tumor against backgound enhancing pancreas. Hypodense CT. T1 Hypointense. Ill-defined. Hypovascualr. Double duct sign
Unresectable pancreatic cancer factors?
Vascular encasement (SMA or Celiac). Direct invasion of adjacent organs. Liver metastasis. Adenopathy. Ascites (peritoneal spread).
5 vessels that matter for surgical resection of pancreas
Celiac, SMA, Hepatic artery, SMV, Portal vein.
Trousseau’s sign
spontaneous venous thrombosis in pancreatic adenocarcinoma
Normal size of duodenal papilla?
Less than 1.5 cm.
Acinar Cell carcinoma of pancreas (demographics, clinical triad of lipase hypersecretion syndrome)
Elderly males. Lipase excretion causes; subcu fat necrosis, bone infarcts causing polyarthralgias, eosinophila
DDx for pancreatic mass w/ no ductal dilatation (8)
Autoimmune pancreatitis, groove pancreatitis, cystic pancreatic tumor, neuroendocrine tumor, Duodenal GIST, lymph node, mets, lymphoma
Pancreatic Mucinous Cystic Neoplasm features. Location, Ductal communication. calcifications
Mother tumor. Malignant potential. No ductal communication. Peripheral calcifications. 80& in the tail. Few large lesions (<6 cysts that are over 2 cm)
Serous cystadenoma. Ductal communication, calcification, vascularity
Grandma tumor, benign, no ductal communication, central calcifications (central stellate calcification), variable location. Many cysts (>6 cysts that are <2cm). Hypervascular.
Classic features of Serous Cystadenoma. (Vascularity? associated syndrome? calcs?)
Hypervascular. A/w VHL. Central calcification and scar
IPMN
Grandfather tumor, Ductal Communication. Can be aggressive.
IPMN should be resected if..
Over 3 cm in size. Mural nodule, pancreatic duct >10mm. Arising from main branch
IPMN Side branch vs. main branch. which is worse?
Main branch is worse. It should be resected.
IPMN classic appearance on endoscopy
Fish mouth papilla pouring out mucin.
Solid and Papilary endothelial neoplasm (SPEN). Appearance. Malignant potential?
“Daughtor tumor” Always in Asians or black girls. Low malignant potential. Large/heterogenous. Hemorrhagic. SPEN has a capsule (like Mother like daughter)
Differential for Solid mass in the tail of the pancreas (2)
Spen. Accessory spleen (1-3 cm, will follow spleen on all phases).