Pancreatic and Urinary Disorders Week 3 Flashcards

1
Q

The pancreas has both ________ and ________ functions.

A

Endocrine, exocrine

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2
Q

The exocrine tissue of the pancreas is responsible for the secretion of what?

A

Digestive enzymes such as typsin, amylase and lipase, and bicarbonate ions.

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3
Q

The endocrine tissue of the pancreas is responsible for the secretion of what?

A

The islets of Langerhans secrete insulin, glucagon and gastrin.

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4
Q

What does Trypsin digest in the body?

A

Proteins

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5
Q

What does Amylase digest in the body?

A

Carbohydrates

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6
Q

What does Lipase digest in the body?

A

Fats

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7
Q

Which cells of the isleets of Langerhans secrete insulin?

A

Beta cells

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8
Q

Which cells of the isleets of Langerhans secrete glucagon?

A

Alpha cells

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9
Q

Which cells of the isleets of Langerhans secrete gastrin?

A

G cells

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10
Q

What is the purpose of bicarbonate ions secreted from the pancreas?

A

It neutralises the chyme from the stomach.

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11
Q

Where are bicarbonate ions secreted from and what path do they follow?

A

Secreted from the exocrine tissue of the pancreas. They exit pancreas through the pancreatic duct which merges with the common bile duct and is drained into the duodenum.

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12
Q

What are some of the aetiologies of Acute Pancreatitis?

A

Gall stones, trauma, alcohol, drugs, hypercalcaemia, atherosclerosis/ischaemia, vasculitis, mumps, idiopathic

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13
Q

How do gall stones cause acute pancreatitis?

A

Gall stones can lodge in the common bile duct causing inflammation in the pancreas.

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14
Q

How does hypercalcaemia cause acute pancreatitits?

A

Calcium deposits in the pancreas causing inflammation.

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15
Q

How does vasculitis cause acute pancreatitis?

A

Inflammation of the surrounding vessels causes the pancreas to become inflamed.

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16
Q

How do the Mumps cause acute pancreatitis?

A

The Mumps usually affects the parotid gland but in a small proportion of people it can cause pancreatitis, inflammation of the testes or the ovaries.

17
Q

What are some of the symptoms of acute pancreatitis?

A

Epigastric discomfort, nausea, vomiting or severe abdominal pain radiating to the back.

18
Q

What happens to the pancreas during acute pancreatitis?

A

Release of pancreatic enzymes leading to coagulative necrosis, fat necrosis, haemorrhage and acute inflammation.

19
Q

Patients with the nephritic syndrome present with haematuria as a key symptom. True or false?

A

True.

20
Q

What are the common clinical features of diabetes mellitus?

A

Hyperglycaemia and polyuria.

21
Q

Acute pyelonephritis may present with pain from which area?

A

Flank or loin pain.

22
Q

Patients with membranous nephropathy present with the nephrotic syndrome. True or false?

A

True.

23
Q

What are some of the causes of chronic renal failure?

A

Chronic glomerulonephritis
Renal artery stenosis
Chronic pyelonephritis