Pancreatic - General

Question 1

Answer 1

Chronic pancreatitis with sclerosis

Low power is important!!!

Question 2

Answer 2

Chronic pancreatitis – believe it or not!

You can see marked reactive atypia and sclerosis!

Question 3

Answer 3

Question 4

Features to report in PDAC

Answer 4

Question 5

Answer 5

Cancerization of pancreatic ducts

Question 6

Pancreatic NET categories

Answer 6

Question 7

Answer 7

Question 8

Molecular alterations in pancreatic NET and pancreatic NEC

Answer 8

Question 9

Acinar cell neoplasms of the pancreas

Answer 9

Question 10

Frequency of acinar cell carcinomas

Answer 10

1-2% in adults
15% in kids

Question 11

Lipase hypersecretion syndrome

Answer 11

Associated with acinar cell carcinoma

Question 12

Answer 12

Acinic granules! A clue to an acinar cell carcinoma. They stain positive on PAS-D shown here. Prominent nucleoli and mitotitc activity are also often present.

Question 13

Acinar cell carcinoma immunophenotype

Answer 13

Question 14

Answer 14

Mixed acinar cell neuroendocrine tumor

Question 15

Molecular alterations in ACC

Answer 15

Question 16

Answer 16

Squamous morules are also often present – which stain positive for beta catennin.

Question 17

Solid pseudopapillary neoplasm usually occurs in. . .

Answer 17

Young women

1:9 M:F ratio, mean age 28

Can happen in kids too

Question 18

Immunophenotype of solid pseudopapillary neoplasm

Answer 18