Pang Flashcards

1
Q

What is the most commonly used parenteral anesthetic?

A

propofol

both induction and maintenance

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2
Q

What receptor does propofol activate?

A

GABAa

no analgesia
induces anesthesia
antiemetic

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3
Q

What is half life of midazolam?

A

2hr

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4
Q

Benzos do not produce true anesthesia

a. true
b. false

A

a. true

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5
Q

Propofol should be frozen for storage

a. true
b. false

A

b. false

store at 5-25C
room temp is acceptable

use strict aseptic technique when handling

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6
Q

Propofol has high oral bioavailability

a. true
b. false

A

b. false

ZERO oral bioavailability

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7
Q

The prodrug fospropofol is metabolized by what enzyme?

A

alkaline phosphatase

present in all tissues

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8
Q

Ketamine is a glutamate (NMDA) receptor agonist

a. true
b. false

A

b. false

ANTAGONIST

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9
Q

ketamine does not cause respiratory depression

a. true
b. false

A

a. true

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10
Q

Most common AE of ketamine when used for anesthesia?

A

emergence (waking up) reactions

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11
Q

Ketamine causes a transient __ in blood pressure, heart rate, cardiac output

a. increase
b. decrease

A

a. increase

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12
Q

Dexmedetomidine is a selective ___

a. alpha 1 agonist
b. alpha 2 antagonist
c. alpha 1 antagonist
d. alpha 2 agonist

A

d. alpha 2 agonist

activates sleep pathways

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13
Q

Dexmedetomidine causes analgesia

a. true
b. false

A

a. true

sedation, analgesia, anxiolytic

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14
Q

Dexmedetomidine does not cause respiratory depression

a. true
b. false

A

a. true

experience close to normal sleep

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15
Q

The -curonium drugs are __

a. depolarizing blockers
b. competitive/non-depolarizing nAChR agonists
c. competitive/non-depolarizing nAChR antagonists

A

c. competitive/non-depolarizing nAChR antagonists

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16
Q

Which has half life of 45 minutes

a. rocuronium and vecuronium
b. pancuronium and cisatracurium

A

a. rocuronium and vecuronium

17
Q

Which has half life of 90 minutes?

a. rocuronium and vecuronium
b. pancuronium and cisatracurium

A

b. pancuronium and cisatracurium

18
Q

Succinylcholine is a nicotinic acetylcholine receptor antagonist

a. true
b. false

A

b. false

agonist

19
Q

Which is a depolarizing block?

a. phase I
b. phase II

A

a. phase II

effect augmented by acetylcholine inhibitors

20
Q

Which is a non-depolarizing block?

a. phase I
b. phase II

A

b. phase II