Paper 3

Question 1

Infectious

Q.Atypical lymphocytes are found in -

Answer 1

A.Mumps
B.Rubella
C.Dangue
D.EBV
E.HIV

Question 2

Immunology

Confirmatory diagnosis of anaphylaxis?

Answer 2

Serum mast cell tryptase

Question 3

Infectious

Autoinfection caused by?

Answer 3

যাদের বুকের ভিতর আগুন💥💥 জ্বলে তাদের autoinfection হতে পারে।

parasite causes Autoinfection :
CHEST
C-Cryptosporidium
H-H.Nana
E-E.V
S-S.S
T-T.solium

এইগুলো দিয়ে ইনফেকশন হলে Auto বুকে আগুন 💥💥জ্বলবে।

Question 4

infectious

Return traveller with Abdominal pain and gradual onset bloody diarrhoea with long incubation period highly suggestive of?

Answer 4

Amoebiasis

Question 5

infectious

Overgrowth of which organism most likely to cause Bacterial vaginosis?

Answer 5

Gardenella

Question 6

Infectious

#STI

What are the diseases and organisms causing those?

1. Painless Ulcer + Painless Lymph Node….?
2. Painless Ulcer + Painful Lymph Node?
3. Painful Ulcer + Painful Lymph Node?
4. Painful Ulcer+ Painless Lymph
   Node?

Answer 6

1. Syphillis
2. LGV, Granuloma Inguinale(less involve LN)
3. Chancroid, Genital Herpes
4. Anal Chancre.

Question 7

infectious

1.Commensals kf oral cavity?

Answer 7

AC তিনটা A, আর candida

-Alpha hemolytic streptococcus
-Actinomyces
-anerobic gm negative(fusobacterium,prevotella)
-Candida

★★★মুখে staphylo নাই

Question 8

infectious

1.commensal of Nares

Answer 8

staphylococcus (সব)

Question 9

infectious

Commensals of skin?

Answer 9

1.Staphylococcus
2.corynebacterium spp
3.prorionibacterium
4.Malassezia

Question 10

infectious

Commensal of vagina

Answer 10

Bcg sle

Bacteroids
Candida,corynebacterium
GBS,gardenella
St,Aureus
Lactobacilus
Enterobacteriacea

Question 11

Which PG is responsible for fever in preoptic nucleus of hypothalamus?

Answer 11

Pg E2

Question 12

Infectious

1.What are normal human Immunoglobulins (pooled IGl & what are specific?

Answer 12

1.Normal:Measles,Hep A

2.Specific:Hep A,Rabies,Tetanus.c.pox

Question 13

Infectious

1.Live vaccines?

Answer 13

Vari MORTal

Varicella zoster
MMR
OPV
ROTA
TYPHOID,TB

Question 14

Infectious

What are killed vaccine?

Answer 14

RICH

Rabies,IPV,influenza,Cholera,Hepa A

Question 15

Infectious

Viral vector vaccines?

Answer 15

1.Covid 19
2.Ebola
3.Dengue

Question 16

Infectious

Nucleic acid vaccine?

Answer 16

1.Covid 19
2.Ebola

Question 17

Infectious

What are 30S ribosome inhibitors?

Answer 17

1.Aminoglycosides
2.Tetracycline

Question 18

Infectious

50s inhibitors?

Answer 18

1.Chloramphenicol
2.Macrolides(erythtomycin)
3.Lincosamines(clindamycin)
4.Linezolid
5.Fusidic Acid

Question 19

Infectious

Nucleic Acid inhibitors?

Answer 19

1. Nucleotides inhibitions :
   ★Sulphonamides:dihydropteroate inhibitions
   ★Trimethoprim:Dihydrofolate synthase inhibitions

2.RNA inhibitions : Rifampicin
3.DNA inhibition: Fluoroquinolones,Metronidazole

Question 20

Infectious

M/A of quinolones?

Answer 20

DNA synthesis inhibitor

Question 21

Infectious

Cell membrane inhibition?

Answer 21

Polymixin
Daptomycin

Question 22

Infectious

M/A of anti TB?

Answer 22

1.Rifampicin-RNA synthesis inhibitor
2.Isoniazid-Inhibit mycolic acid synthesis
3.Pyrazinamide- inhibit fatty acid synthesis
4.Ethambutol-inhibit arabinogalactan synthesis

Question 23

Infectious

Anti pseudomonal?

Answer 23

মনে রাখব ABC + Meropenem

1.Aztreonam
2.Brodactum(piperacillin Tazobactum)
3.Ciprofloxacin,cefepime,ceftazidime
4.Meropenem

Question 24

Infectious

Anti MRSA?

Answer 24

1.Clindamycin
2.Linezolid
3.Co trimoxazole
4. Vancomycin
Tigecycline,rifampicin,tetracycline

Question 25

#Infectious Resistence

Answer 25

1.By efflux pump: ★Tetracycline ★fluconazole টেট্রা আর ফ্লুকোনাজল কে লাত্থি দিয়ে বের করব। ২.Impermeable: ★Carbapenem ★Aminoglycosides কারবাপেনাম আর এমাইনোগ্লাইকোসাইড কে ঢুকতেই দিবে না। আমিনের কার ঢুকতে দিবে না। আমিন-Amino,কার -Carbapenem 3.Enzymatic degradation: ★Penicillinase:Beta lactam ★NDM1:Enterobactetiacae ★CAT:Chloramphenicol in staphylococcus 4.Modification of target site (বাকী সব গুলা) ★MRSA- to Beta lactum Modification of PBP ★Glycoprotein(vancomycin) resistance in Enterococci-Altered peptidoglycan aminoacid sequence. ★Rifampicin in MTB: RNA polymerase mutation ★ciprofloxacin(quinolones) in Enterobactetiacae : DNA gyrase alteration ★Linezolid in staphylococcus & Enterococci- 23 S rRna methylation ★Macrolides: Bacterial ribosomal Methylation ★Vancomycin- D ala D Ala to D ala D Lac

Question 26

#Infectious Which is the only indication of spectinomycin?

Answer 26

Gonococcal urethritis in PG

Question 27

#Infectious Post transplan infection

Answer 27

★Solid organ 0-1 month: Bacteria,fungal infection related to underlying condition and surgery 1-6 month: CMV,PCP >6 month: বাকী সব ★Post stem cell: 0-4 wks: Bacterial,fungal HSV reactivation Early <100 days : CMV PCP late>100: বাকী গুলা

Question 28

#Infectious Blood stream infections.

Answer 28

1.Predominant Community acquired: Streptococcus গুলা (entero coccus বাদে) 2.Both: E.COLI & st. aureus (including MRSA) 3. Predominantly hospital acquired: st epidermidis,pseduomonas,enterobacteriace (except E.coli) Enterococci,Candida

Question 29

#Infectious কোন দুইটা colon ca এর সাথে রিলেটেড

Answer 29

S.galolyticus Clostridium septicum

Question 30

Which organisms are responsible for Necrotizing fascitis in Marine exposure & CLD?

Answer 30

1.Aeromonus Hydrophilia 2.vibrio vulnificus ★Necrotizing fascitis type 3 করবে। ★Type 2 - streptococcal toxic shock syndrome এর সাথে Association

Question 31

Commonest regimen for HAART

Answer 31

ইফা র এম টেন Efavirenz or Raltegravir plus Emtricitabine plus Tenofovir দুইটা NRTI সাথে অন্য গ্রুপের একটা। Efavirenz avoided in PG

Question 32

#Respiratory Lung compliance : প্রতি ১ cm H20 transpulmonary pr বাড়লে লাং ২০০ ml এক্সপান্ড করে। increase compliance?

Answer 32

1.AGe (OlD age>child) 2.Emphysema(obstructive disease) 3.Sranding

Question 33

#Respiratoty Repeated sino Pulmonary infection + Bronchiectasis

Answer 33

Young syn.

Question 34

#Respiratory Features of primary TB due to Hypersensitivity?

Answer 34

End diastolic pr is due to primary tb hypersensitivity 1.Erythema nodosum 2.Dactylitis 3.phlyctenular conjunctivitis

Question 35

Non pulmonary complications of pulmonary TB?

Answer 35

1.Empyema Necessitans 2.Laryngitis 3.Enteritis,Anorectal disease 4.Amyloidosis 5.poncents arthropathy