Paracetamol

Question 1

Paracetamol - Mechanism of action

Answer 1

Inhibits the production of prostaglandins, resulting in a reduction of pain and fever.
It is metabolised in the liver.

Question 2

Paracetamol - Indications

Answer 2

Mild or moderate pain, usually in combination with other medicines.
May be administered with other medicines for severe pain if transport time is long.

Question 3

Paracetamol - Contraindications

Answer 3

Known severe allergy.

Question 4

Paracetamol - Cautions

Answer 4

Patient has taken paracetamol in last 4 hours.
Abdominal pain, esp if unwell or vomiting.
Known severe liver disease.

Question 5

Paracetamol - Dosage

Answer 5

1.5g PO for adult greater than 80kg.
1 g PO for adult 80kg or less.
See paediatric drug dose table for a child.

Question 6

Paracetamol - Common side effects

Answer 6

None.

Question 7

Paracetamol - Onset of effect

Answer 7

30-60 minutes

Question 8

Paracetamol - Duration of effect

Answer 8

4 - 6 hours.

Question 9

Paracetamol - Preparation

Answer 9

500mg tablets.

Syrup containing 50mg/ml.

Question 10

Paracetamol - Repeats

Answer 10

None