Parkinson's Disease Flashcards
1
Q
Parkinson’s Disease =
A
Common neurodegenerative disorder characterised by degeneration of dopamine-producing cells in the substantial nigra, which results in bradykinesia, rigidity and resting tremor.
2
Q
Classic Triad of Symptoms
A
Bradykinesia
Rigidity
Resting Tremor
3
Q
Other Features of PD:
A
- Loss of postural reflexes
- Changes in facial expression
- Changes in speech
- Altered posture
- Difficulty initiating voluntary movement
- Changes in gait
- Freezing of movement
- Micrographia
- Dementia
- Depression
- Hallucinations
- Burning mouth syndrome
4
Q
Drug Treatment
A
- Levodopa
- Dopamine Agonists
- MAOIs and COMTs
- Anti-muscarinic Drugs
