Part 1 Flashcards

(50 cards)

1
Q

Antibiotic associated with: teeth discoloration

A

tetracyclines

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2
Q

Antibiotic associated with: tendonitis

A

fluroquinolones

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3
Q

Antibiotic associated with: red man syndrome

A

vancomycin

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4
Q

Antibiotic associated with: grey baby syndrome

A

chloramphenicol

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5
Q

Antibiotic associated with: cartilage damage in children

A

fluoroquinolones

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6
Q

Antibiotic associated with: nephrotoxicity (esp. when paired with what other drugs?)

A

aminoglycosides with cephalosporins

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7
Q

Antibiotic associated with: ototoxicity (esp. when paired with what other drugs?)

A

aminoglycosides with loop diueretics

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8
Q

Drugs that are assoc. with both ototoxicity and nephrotoxicity?

A

aminoglycosidesvancomycinloop diureticscisplatin

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9
Q

Antibiotic assoc. most with pseudomembranous colitis?

A

ampicillinclindamycin

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10
Q

DOC for gonorrhea

A

ceftriaxone

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11
Q

DOC for Lyme disease or Rocky Mountain spotted fever?

A

tetracyclines

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12
Q

DOC for Giardia lamblia

A

metronidazole

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13
Q

DOC for MRSA and C. difficile colitis

A

vancomycin

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14
Q

Tx for gram(-) rods in renal insufficiency

A

aztreonam

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15
Q

BIG GUN effective in gram(+) cocci, gram(-) rods, anaerobes

A

meropenemimipenem with cilastatin

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16
Q

Prophylaxis in AIDS patients against P. pneumonia

A

TMP-SMXdapsonepentamidine

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17
Q

Solo prophylaxis against TB

A

Isoniazid

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18
Q

Antibiotics safe during pregnancy

A

penicillins, aminopenicillinspiperacillincephalosporinsmacrolides (erythromycin and azithromycin)metronidazole (after 1st trimester)nitrofurantoin

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19
Q

Hesselbach’s Triangle

A

Superior + Lateral = Inferior epigastric artery
Medial = Lateral border of rectus abdominus
Inferior + Lateral = Inguinal ligament

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20
Q

Orotic acid in urine + elevated serum ammonia

A

OTC deficiency

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21
Q

Orotic acid in urine + NO elevations of serum ammonia

A

Orotic aciduria

22
Q

Boy with lip-biting self mutilation, intellectual disability, gout

A

Lesch-Nyhan syndrome

23
Q

Megaloblastic anemia that does not improve with folate and B12

A

Orotic aciduria

24
Q

Major causes of post-op fever:

A

5 W’s

Wind -  Pneumonia
Water - UTI
Wound - wound infection
Walking - DVT
Wonder drugs
25
Macrolide coverage
PUS Pneumonias URIs (group A strep) STDs
26
Tetracyclines coverage
VACUUM THe BEDRoom ``` Vibrio cholerae Acne Chlamydia Ureaplasma Urealyticum Mycoplasma pneumoniae Tularemia H. pylori Borrelia burgdorferi Rickettsiae rickettsii ```
27
2nd gen ceph coverage
``` H. flu Enterobacter Neisseria Proteus mirabilis E. Coli Klebsiella Serratia **also gram(+) cocci ```
28
Pregnant woman BP drops to BP when supine: Diagnosis?
compression of IVC
29
Drugs used reverse neuromuscular blockade with non-depolarizing drugs
Cholinesterase inhibitors (neostigmine)
30
Mechanism of action of dantrolene
prevents release of calcium from sarcoplasmic reticulum of skeletal muscle
31
What substances inhibit reuptake of norepinephrine?
cocaine | TCAs
32
Boot-shaped heart
RVH in Tetralogy of Fallot
33
Continuous machine-like murmur
PDA
34
Tendon xanthomas seen in
Familial hypercholesterolemia
35
Cafe-au-lai spots -
NF1, McCune-Albright snydrome
36
Tuft of hair on lower back
occult spina bifida
37
Seizures Intellectual disability Angiofibroma
tuberous sclerosis
38
Most common cause of hypoparathyroidism?
thyroidectomy
39
Most common cause of mets to brain?
Lung and breast cancer melanoma renal cell CC GI tumor
40
Most common lysosomal disease?
Gaucher disease
41
Most common cause of myocarditis?
Coxsackievirus, echovirus
42
Amniotic fluid measurement indicative of fetal lung maturity
Lecithin to sphingomyelin ratio > 2.0
43
Substance responsible for release of NE from neurons?
Calcium Other substances: amphetamines ephedrine tyramine
44
Which cytokines inhibit Th1 cells?
IL-10
45
Aqueous humor pathway
Ciliary body --> posterior chamber --> iris and lens angle --> anterior chamber --> reabsorbed in canal of Schlemm
46
MOA of metoclopramide
D2 receptor antagonist | 5-HT agonist
47
Pudendal block landmark
Ischial spine
48
RLE of carbohydrate digestion
oligosaccharide hydrolases found in intestinal brush border
49
What vitamin deficiency results from Hartnup disease?
Niacin Tryptophan deficiency yield Niacin deficiency
50
Dantrolene used for:
Neuroleptic malignant syndrome | Malignant hyperthermia