Parts of the brain Flashcards

1
Q

How many ventricles in the brain?

A

4
2 lateral and 2 ventricle

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2
Q

Which ventricle can only been seen by the sagittal view?

A

4th

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3
Q

What is the purpose of the ventricles ?

A

communicating network
cavities filled with csf (made by choroid plexus) to help buoyancy

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4
Q

What is the size of the ventricles dependent on ?

A

cortical atrophy (ventricular enlargement when neurones are lost)

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5
Q

What are the following lobes involved in ?
- frontal
- parietal
- occipital
- temporal

A

frontal = mood, behaviour, decisions
Parietal = sensory
Occipital = visual
Temporal = spatial navigation, language, auditory

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6
Q

What is the name of the bundle of nerve fibres which join the hemispheres together ?

A

Corpus callosum

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7
Q

What experiment did Roger Sperry carry out ?

A

Cut the corpus callosum to cause lack of communication between hemisohere to stop the seizures caused by epilepsy

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8
Q

What does the thalamus do?

A

relay station for sensory info

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9
Q

What does the basal ganglia do?

A

involved in extrapyramidal motor control
(pyramidal = cortical spinal tract)

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10
Q

What is extrapyramidal motor control?

A

Initiation and fine control of movement (can also inhibit movement)

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11
Q

What happens if the sub thalamic nuclei is damaged?

A

Give rise to ballismus (uncontrolled movement of limbs)

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12
Q

What does the striatum do?

A

dopamine rich
important in extrapyramidal control and impact on mood

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13
Q

What does the limbic system control?

A

emotion and mood

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14
Q

What are the key nuclei within the limbic system ?

A

Amygdala, hypothalamus, hippocampus

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15
Q

Where is the amygdala located?

A

Basal forebrain

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16
Q

Give examples of the catecholamines in the brain

A

Dopamine, adrenaline/epinephrine, noradrenaline/noraepinephrine

17
Q

What are the dopamine nuclei?

A

substantia nigra, ventral tegmental area and arcuate nucleus of the hypothalamus

18
Q

Where is 5-HT sythesised and what is the structure ?

A

Synthesised in raphe nuclei
Indoleamine

19
Q

What is fMRI?

A

Functional magnetic resonance imaging
Based on the face oxyhemoglobin (has different magnetic resonance than deoxy)

20
Q

What’s the resolution of an MRI?

A

less than 1mm

21
Q

What can be used to map pathways and connectivity in the brain?

A

diffusion tensor imaging

22
Q

What does PET stand for ?

A

positron emission tomography

23
Q

What does SPECT stand for ?

A

single photon positron emission tomography

24
Q

What are some non-invasive ways to reveal activity of the brain?

A

EEG
MEG
PET scan
SPECT scan

25
Q

What are the indirect markers for changes in NT function?

A

Cerebrospinal fluid (invasive but closer to where metabolites formed)
Plasma
Urine
Binding platelets

26
Q

What are the advantages and disadvantages of using animal models?

A

Ad = drug screening
Disad = not exact phenocopy of gene