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RUSVM Virology Fall 2015 > Parvoviridae > Flashcards

Parvoviridae Flashcards

1
Q

What does the family Parvoviridae have in common with Circoviridae in terms of DNA structure?

A

Single stranded

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2
Q

What reaction do Parvoviruses have with erythrocytes?

A

Hemagglutination

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3
Q

Where do Parvoviruses replicate?

A

Nucleus

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4
Q

What are the 2 subfamilies of Parvoviridae and?

A
  1. Parvovirinae

2. Densovirinae

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5
Q

What are the 5 genera within the subfamily Parvovirinae?

A
  1. Bocavirus
  2. Erythrovirus
  3. Parvovirus
  4. Dependovirus
  5. Amdovirus
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6
Q

What must a cell undergo in order for Parvoviruses to replicate inside of them?

A

S-phase of mitosis

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7
Q

Parvovirus B19 infects humans, which genus does it belong to?

A

Erythrovirus

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8
Q

What is required for members of the genus Dependovirus to replicate?

A

Helper virus, usually an adenovirus

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9
Q

What is unique about Bocaviruses compared to other parvoviruses?

A

Contain a 3rd O.R.F. between coding and non-coding regions

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10
Q

What disease in cats is caused by feline parvovirus?

A

Feline panleukopenia

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11
Q

T/F FPV is so contagious that 75% of unvaccinated cats will have a positive antibody titer at 1 year of age.

A

True

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12
Q

Which is more responsible for the maintenance of FPV? Environmental persistence or extended viral shedding

A

Environmental persistence

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13
Q

Which leukocytes are relatively safe compared to the others in a cat infected with FPV?

A

Trick quesiton- they are all up for destruction

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14
Q

What can also occur in FPV infections, alongside leukopenia, if the bone marrow is damaged?

A

Thrombocytopenia

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15
Q

Which cells being destroyed by FPV are responsible for enteritis associated with the disease?

A

Deep replicating crypt stem cells

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16
Q

When does nervous tissue damage usually occur in FPV infections?

A

Pre-natal infection

17
Q

How is the cerebellum usually affected by FPV?

A

Cerebellar hypoplasia

18
Q

What would cause a kitten with FPV to experience Disseminated Intravascular Cougulation?

A

Secondary bacterial infections

19
Q

FPV Clinical Signs?

A 
Diarrhea
Lymphopenia
Neutropenia
Thrombocytopenia
Anemia
Abortion, resorption
Cerebellar ataxia

RUSVM Virology Fall 2015 (6 decks)

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