PassMed learning Flashcards

1
Q

Atypical antipsychotic associated with the least side effects

A

Aripriprazole (particularly good for patients with prolactin elevation using other APs)

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2
Q

Key side effects of antipsychotics

A

Prolactin elevation
Weight gain
Stroke/ VTE
Low white cells (clozapine)

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3
Q

Side effect profile of clozapine

A

Agranulocytosis and neutropenia

Reduced seizure threshold
Constipation
Hypersalvation
Myocarditis (baseline ECG before)

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4
Q

When can clozapine be introduced

A

Schizophrenia when 2 other antipsychotics have failed for 6-8 weeks each

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5
Q

Definition of somatisation disorder

A

Multiple physical symptoms present for 2+ years
AND
Patients refuses to accept negative results

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6
Q

Definition of hypochondriasis (illness anxiety disorder)

A

Persistent belief in presence of underlying disease

Patient refuses to accept negative results

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7
Q

Difference between somatisation and hypochondriac

A
Somatisation = symptoms (multiple for at least 2 years)
Hypochondriac = disease belief

Both refuse to accept negative results

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8
Q

Conversion disorder definition

A

Patient loses motor or sensory function

Does not consciously fake the symptoms

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9
Q

What is Munchausens syndrome

A

Intentional production of physical or psychological symptoms

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10
Q

What is malingering

A

Fraudulent simulation or exaggeration of symptoms for gain (normally financial)

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11
Q

What is dissociative disorder

A

Separating off certain memories from normal consciousness

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12
Q

What psychiatric drug increases risk of VTE in elderly

A

Atypical antipsychotics

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13
Q

Name 2 main typical antipsychotics

A

Haloperidol

Chlorpromazine

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14
Q

When should lithium levels be monitored in a patient starting treatment today and continuing for 2 years

A

12 hours after dose

Every week until stable

Every 3 months then on

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15
Q

Catatonia definition

A

Inability to move correctly

Abnormal movements

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16
Q

First line treatment for anorexia in children

A

Focused family therapy

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17
Q

Two types of bipolar?

A

1: Depression and mania (psychotic beliefs lasting more than 7 days)
2: Depression and hypomania

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18
Q

Treatment for OCD if mild vs severe

A

Mild: CBT
Severe: SSRI

Fluoxetine for body dysmorphic disorder

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19
Q

Two common monoamine oxidase inhibitors

A

tranylcypromine and phenelzine

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20
Q

Why are monoamine oxidase inhibitors not really used

A

Cannot consume tyramine containing foods (cheese, marmite, broad beans)

As causes hypertensive reaction

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21
Q

What is rasagaline

A

Inhibitor or monoamine oxidaseB used to treat Parkinson’s

22
Q

What are clang associations

A

Ideas that are linked by rhyme or similarity of word sounds alone. This is sometimes seen in schizophrenia or bipolar disorder.

23
Q

What is avoidant personality disorder

A

Avoid social activities
Preoccupied with ideas that they are rejected in social situations
Isolate them self but crave interaction

24
Q

What is key symptoms of borderline personality disorder

A

Emotionally unstable

Avoid abandonment

25
Difference between Knights Move thinking and flight of ideas
KM: no connection between ideas FOI: some connection, however remote
26
Key side effect of atypical AP vs typical AP
Weight gain
27
Drug management for bipolar
Lithium Antipsychotic can be used at low dose (quetiapine (sedative)) Antiepileptics for mood stability
28
In patients presenting with ?anorexia what is a key first part of the assessment
Physical state - including HR temp BMI
29
What is anankastic personality disorder
OCD
30
What is conversion disorder
When a person develops blindness or paralysis
31
Key difference between panic disorder and GAD
Panic disorder is short spells that happen acutely and last a few minutes
32
Patient with broad based gate, confusion and delusions. What needs to be given
Thiamine first!! This is Wernicke's
33
Urine left for 3 days - turns red... What is it and whats the cause
Porphyria Liver disfunction
34
Man insists wife is unfaithful and sleeping with whole neighbourhood - DX?
Othello syndorme
35
What is dissociative fugue
After a stress, people temporarily lose their identity and wander away from their homes
36
What is agroraphobia
Anxiety disorder that causes fear of social situations that might cause embarrassment, helpless or trapped
37
What is cortards syndrome
Belief one is dead, missing blood or organs
38
Other than lithium what cases of drugs can be used in BP disorder
Anti psychotics for short periods of mania | Anti epileptic as mood stabiliers
39
SSRI contraindicated with UGI bleeds
Fluoxitiene
40
SSRI of choice in children
Fluoxetine
41
How to manage hypomania in primary care
Routine referral to community mental health
42
How should an SSRI be stopped
Over 4 weeks slowly
43
Compulsion vs obsession
Compulsion is a senseless action taken to remove an anxiety Obsession is an intrusive unwanted thought O->C Hands dirty -> wash them
44
SSRI of choice in patients with cardiac conditions
Sertraline
45
Main electrolyte disturbance from an SSRI
hyponatraemia
46
Difference between acute stress reaction and PTSD
Acute stress reaction up to 4 weeks
47
If CBT fails, first line drug in PTSD
Venlafaxine
48
How long must symptoms last to become a depressive episode
Only 2 weeks
49
How to treat lithium toxicity
Fluid resuscitation
50
Worse SSRI for QTC prolongation
Citalopram
51
Anti depressants that causes prolonged QTC
TCAs, Citalopram, venlafaxine