Past Qs Flashcards

1
Q

2 key features of early dementia

A
	Memory lapses
	Forgetting names of people and places
	Difficulty finding words for things
	Inability to remember recent events
	Forgetting appointments
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2
Q

Other than RSV other organisms causing bronchiolitis

A

 Human metapneumovirus (second most common)
 Adenovirus
 Parainfluenza virus

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3
Q

2 auscultation signs of bronchiolitis

A

 Widespread fine inspiratory crackles

 Expiratory wheeze

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4
Q

When cxr On bronchiolitia

A

Should only be performed if there is diagnostic uncertainty or atypical course

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5
Q

2 bits of advice for parent on bringing child back after discharge of bronchiolitis

A

 To return if develops any signs of respiratory distress
 If not tolerating fluids
 If there is any history of apnoea

Worsening

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6
Q

Endocarditis usual valve

A

tricuspid

[Think IVDU -> return of blood to RIGHT side of heart]

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7
Q

Why JVP in IE tricuspid

A

tricuspid regurge -> not able to prevent backflow of blood

-> rise in RA pressure

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8
Q

Why long term abx in IE

A

Neither the heart valves nor the vegetations adherent to them are supplied by blood vessels.

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9
Q

IE develops PE

Mx

A

Drug Heparin
Route Subcutaneous

Oxygen 100%
Route of O2 Non-rebreather mask with reservoir

Analgesia Morphine

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10
Q

Electrolyte abnormalities in DKA

A

hyperK - (overal stores low)

High anion gap

Low Na (if dehydrated) 
-also raised urea / creatinine
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11
Q

Hydrocele
2 causes

Where is fluid

what test for GP

3 things you feel for on scrotal exam

A

 Trauma
 Tumour
 Epididymo-orchitis

tunica vaginalis

transilluminate

Epididymis, testis, vas deferens

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12
Q

3ix and 2 drugs for MS

A

3 Ix
 Evoked potential testing (e.g. visual, auditory, somatosensory)
 MRI scan of brain/spinal cord
 LP for CSF analysis showing oligoclonal bands

Management
Beta-interferon, natalizumab

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13
Q

3 components of bishops score

A

length, position, dilatation, consistency of cervix. Head station

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14
Q

Who can you give PSA

A

over 50 with lower urinary Sx / request

Monitoring of prostate cancer resection

Suspicious PR findings

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15
Q

young guy wants PSA - what Should you do ?

A

Reassure + educate about PSA
PR exam
Urine dip for blood

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16
Q

high Ca - 1st Ix?

A

ECG - Short QT

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17
Q

Initial Mx of hyper Ca - 2nd line?

A
IV Fluids (+furosemide if volume overload) 
Bisphosphonates 

calcitonin

Dialysis

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18
Q

Mx of old post stroke with constipation

A

Improve fibre
Increase fluid intake
Avoid meds which could constipate

Bulk formin lax - Eg Fibrogel

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19
Q

4 meds - > constipaton

A

Opiates
iron tablets
Calcium
Anticholinergics

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20
Q

2 key Ix in pregnant with spotting

A

BHCG

USS

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21
Q

2 drug Mx if incomplete miscarriagre

A

Mifepristone / misoprostol

anti D

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22
Q
Rheum A pre surg 
2 physical pre for anaethetics 
2 radiological 
2 Anaesthetic techniques 
Which should you do? 
Specific comps post op for RheumA on lots of meds
A

Neck extension
Malapati

CXR - Chest
Neck CT / XR

Spinal, Epidural, volatile gas, Total IV anasthetics

IV - Q she was bleeding (no spinal) dont want haematoma there
-Also RheumA may affect Spine

Infection - immunosuppressed
RA = hypercoagulable - VTE
Steroids - poor healing
Steroids - increased risk of pressure ulcer
Comps with intubation due to neck involvement
-may have fibrosed lungs - resp difficulty

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23
Q

Mx intermittent claudication

A

RF modification
Antiplatelet -clopidogrel 1st line
Supervised exercise
Patient education

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24
Q

How to Ix intermittent claudication ? Levels are significant?

A

ABPI
Lie pt flat
Use doppler probe to test bracial and medial maleola arteries
Extringuish with cuff

<0.9 = some arterial disease 
<0.5 = critical ischemia
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25
Why trismus in quinsy
muscle spasm caused by abscess
26
Mx of quinsy
IV fluids - probs dehydrated Analgesia ABx - clindamycin / metronidazole Drain pus
27
Lymph node in quinsy
jugulodigastric node
28
Signs to differentiate torsion and eppididimoorchiditis. Initial Ix
Torsion - red, swollen, transverse lie, vomiting / nausea Absent cremaster Epi - Prehn's sign [lift testi and -> eases pain] Retrotesticular pain USS - see if torsion
29
CURB65 points
``` Confusion Urea >7 Respiratory rate of 30 or more Blood pressure less than 90 mmHg systolic or diastolic 60 mmHg or less Age 65 or older ```
30
When to transfer pneumonia -> ITU
Uraemic - Kidney failure / ureamic encephalopathy septic shock Resp failure - requirement for mechanical ventilation Multi organ support needed
31
CAP levels of Mx
Mx in community - Amox Mx in hosp - Amox + macrolide Eg erythromycin Severe in cost - CoAmox + macrolide
32
Young sporty - develops clicking and pain in hip | 3DDx
OA, Trochanitc bursitis, femoroacetablar impringement
33
Pyelonephritis initial mx
- adequate fluid intake and analgesia | - Start empirical Abx eg Cipro while waiting MC+S
34
Name 3 viral causes of meningitis
HIV, Mumps, HSV, ebv
35
How to NSAIDs / Acei cause kidney failure
nsaids - inhibit prostaglandin -> constrict aferent arteriole - hypoperfusion ACEI - reduce angiotensin 2 -> less tone of efferent arteriole -> more blood flows out
36
Signs an infant is sick
pale/mottled/ashen/blue skin, lips or tongue no response to social cues[3] appearing ill to a healthcare professional does not wake or if roused does not stay awake weak, high-pitched or continuous cry grunting respiratory rate greater than 60 breaths per minute moderate or severe chest indrawing reduced skin turgor bulging fontanelle
37
2 key ways to monitor Renal function in hosp
Urine output | u+e
38
4 ways to have successful consultation with interpreter
``` Speak to pt not interpreter Avoid jargon Short simple sentances Not multiple Questions clarify Allow plenty of time ```
39
Bar capcity 2 things needed for consent
 Free from coercion/voluntary participation  Use understandable terms  Give sufficient time for careful decision-making  Give thorough information  Allow questions and comments
40
Mx asthma emergency? | If life threatening ?
 Sit up and give 15L of O2 via non-rebreathing bag  Salbutamol 5mg + ipratropium bromide 0.5mg nebulised with O2.  Hydrocortisone IV or prednisolone PO  CXR to exclude pneumothorax If life-threatening: o Inform ITU o Add iv magnesium sulphate o IV salbutamol
41
Immediate actions in PEA ? Drug and route?
``` Ensure airway is patent Call crash team Commence CPR Gain IV access Attach defibrillator ``` 1mL adrenaline 1:10,000 IV
42
Why might asthma get VT/VF
VT – salbutamol – long QT | Hypoxia
43
Why do you get acanthrosis nigricans
Increased circulating insulin. This activates keratinocyte ILG-F 1receptors . Increased circulating IGF may lead to keratinocyte and dermal fibroblast proliferation.
44
Pathophys of sickle cell veno-occlusive
Deoxygenated HbS molecules are insoluble and polymerize. RBCs become rigid and take up their characteristic sickle appearance. Sickling leads to 1) decreased red cell survival and 2) impaired passage of cells through the microcirculation, leading to obstruction of small vessels and tissue infarction.
45
Sickle long term Mx
Hydroxycarbamide (hydroxyurea) | Antibiotic prophylaxis / vaccines due to hyposplenism
46
Name 2 lymph nodes around bladder
``` Primary lymphatic drainage of BCa extends into the  internal iliac LNs  external iliac LNs  obturator LNs  presacral LNs Secondary drainage progresses into the  common iliac LNs  para-aortic LNs  interaortocaval LNs  paracaval LNs ```
47
Bloood supply to bladder
Superior and inferior vesical arteries which arise form the iternal iliac artery
48
Key observation I forget in TURP
temperature (hypothermia)
49
4 things that could cause shock post TURP
```  TUR syndrome (absorption of washout causing hyponatraemia)  Sepsis  Bleeding  Clot retention  Pulmonary embolism ```
50
1st rank Sx of schitz
 Delusions of thought interference: thought withdrawal, insertion, or blocking  Delusional perception  Auditory hallucinations (commentary, made in third person)  Delusion of control (passivity of affect, passivity of impulse, passivity of volitions, somatic passivity)
51
Gallstones -> pancreatitis mx
 NBM  NG tube  Set up IVI  Analgesia: pethidine or morphine  ERCP + gallstone removal may be needed if there is progressive jaundice
52
2 Psych Mx for eating disorders
 Cognitive behavioural therapy (CBT) |  Family-based treatment (FBT)
53
2 eye Sx of optic neuritis
 Decreased visual acuity  Painful eye movements  Blurred vision on having a hot bath (Uhtoff’s phenomenon)  Decrease in colour vision
54
MS - weak legs | 4 other signs
 Hypertonia (spasticity)  Increased reflexes  Upgoing plantars  Clonus
55
3 signs of pailloedema on opthalmoscope
venous engorgement - usually first  hemorrhages over and / or adjacent to the optic disc  blurring of optic margins  elevation of optic disc
56
Where does klebsiella live normally
Nose, mouth, GI tract.
57
Which Valve most common in IE and why
Tricuspid valve – most commonly infected valve in IVDU as first valve that bugs come into contact with
58
Most common IE bug? if IVDU?
Alpha haemolytic streptococcus – Streptococcus viridans | Staph aureus is commonest in IVDU
59
puritis due to liver failure mx?>
 Cholestyramine
60
2 esrly signs dementia
amnesia, decreased cognitive function, constructional apraxia, Aphasia
61
2 reasons you would surgically drain SUBDURAL Comps of this?
Focal neurology Riased ICP Seizures Infection, haemorrhage, brain tissue injury, brain oedema, seizures
62
Endocarditis What valve lesion would you see on ECHO? Raised JVP - what abnormality in the wave would you see?
vegetation on the valve Raised V wave
63
Erectile dysfunction 22 male 4 chronic causes 3 Blood tests 3 mx performance anxiety
Diabetes, hypertension, depression, MS Prolactin, testosterone, FSH, LH, SHBG CBT, Sex therapy, Sildenafil
64
Bony landmark on top of scrotum
pubic tubercle
65
Hydrocoele comes from
Processus vaginalis
66
SEVERE UC remission Initial Mx drug and route If failing Remission if Mild?
IV hydrocortisone Cyclosporin / infliximab Sulphasalazine Oral
67
Drug in SAH
nimodipine
68
4 features of brainstem death
No respiratory effort in reaction to turning off ventilator 2. Fixed Pupils unreactive to light 3. No corneal reflex 4. No cough reflex 5. No response to supra orbital pressure.
69
Pericarditis auscultation? 4Ix 2mx
pericardial rub ```  Chest x ray  Bloods esr/crp/WBC  ECG echo biopsy ``` NSAIDS - colchicine steroids
70
Cancer in right hilum smoker = How to biopsy
Squamous cell CT guided
71
Lung Ca features of types
Squamous - Smokers, Hilum - PTH Adeno -Periphery Small cell - bronchus - ADH - ACTH - LEM
72
2 causes and 4 mechanisms for abdo distension
a. bowel obstruction i. adhesions/ recent surgery – most common ii. cancer iii. constipation iv. diverticulitis v. autonomic dysfunction bowel control vi. hernias b. Ascities -Cardiac / liver failure meigs -hypoalbuminaemia
73
3 slit lamp findings anterior uveitis
Keratic Precipitates, Hypopyon, strange shaped pupil
74
Anterior uveitis rare infective cause
HSV
75
Advice when given GTN to pt
headache, call 999 if not relieved after 3 goes
76
Small bowel obstruction XR
Multiple loops central coniventes (full thickness muscular rings) No gas in large bowel
77
Large bowel obstruction
peripheral larger than small bowel presence of haustra
78
Obstruction following surgery top 3 ddx
Adhesions = most likely Hernia Volvulus
79
IBD 2 AXR findings
thumb printing | lead pipe colon
80
2 enzyme inducers (decrease effect of other drugs)
phenytoin rifampicin carbamazepine alcohol [CARP]- Carbamazepine also has CAR at start
81
2 enzyme inhibitors (increase effect of other drugs)
``` SSRIs ciprofloxacin amiodarone diltazem / verapamil Smoking ``` [Can Andy Stop Smoking] -
82
Ipatropium class
SAMA
83
Reversal of heparin
protamine
84
Stroke vessles and Sx
MCA - hemiplegia (especially face/arm) -Can getoptic involvement too Anterior - Weak leg - Siminar / mild arm - SPARES FACE Posterior - Homonymous hemaniopia with macular sparing
85
1 year bleeding risk
H Hypertension: (uncontrolled, >160 mmHg systolic) A Abnormal renal function: Dialysis, transplant, Cr >2.26 mg/dL or >200 µmol/L Abnormal liver function: Cirrhosis or Bilirubin >2x Normal or AST/ALT/AP >3x Normal S Stroke: Prior history of stroke B Bleeding: Prior Major Bleeding or Predisposition to Bleeding L Labile INR: (Unstable/high INR), Time in Therapeutic Range 65 years D Prior Alcohol or Drug Usage History (≥ 8 drinks/week) Medication Usage Predisposing to Bleeding: (Antiplatelet agents, NSAIDs)
86
-Hypokalaemia – 1x symptom and 1x sign o/e
weakness | hypOrelfexia / hypotonia
87
Score post TIA
``` ABCD² age >60 BP > 140/90 Cliical features - speech / unilateral weakness(2) Duration >10mins >1hr (2) Diabetes ```
88
Score for stroke post AF
C Congestive heart failure (or Left ventricular systolic dysfunction) H Hypertension: blood pressure consistently above 140/90 mmHg (or treated hypertension on medication) A2 Age ≥75 years D Diabetes Mellitus S2 Prior Stroke or TIA or thromboembolism V Vascular disease (e.g. peripheral artery disease, myocardial infarction, aortic plaque) A Age 65–74 years Sc Sex category (i.e. female sex)
89
Dx of thalassaemia
Microcytic hypochromic anaemia- FBC Haemoglobin electrophoresis DNA testing
90
Most common lung cancer
squamous (in smokers)
91
Allergy physiology
type 1 hypersensitivity- degranulation of mast cells releasing histamine. IgE medicated
92
4 things to check before heparin
U&E, FBC ( platlet count), LFT, accurate weight
, HASBLED
93
melanoma tumor marker
s-100 

94
vit d metabolism
VIT D skin -> Hydroxylated by liver 25 hydroxy vit D | -> Hydroxylated by kidney 1,25 hydroxy vit D
95
What PTH binds to for bone resorption
RANK-L
96
Why vit D lack -> osteomalacia
lack of Vit D -> reduces Ca | -> Increases PTH which increases osteoclastic activity and bones become undermineralised- i.e osteo malacia
97
Gout 1st line acute ? Long term and class
Naproxen (colchicine if CI) Allopurinol - xanthine oxidase inhibitor -> reduces serum uric acid
98
coealiac rash? tumour risk
dermatitis herpetiformis 
 | MALT Lymphoma
99
Define economic evaluation

Assessment of efficiency, in other words it’s the comparative study of the cost and effectiveness/benefits of a health care intervention 

100
What makes a QALY
Quality and Quanity (age) of life lived 

101
2 things which make an economic evaluation
Cost and effectiveness
102
2 types of economic evaluation
cost benefit analysis, cost utility analysis, cost effectiveness 
analysis, cost minimization analysis
103
Define efficiency 

When resources are allocated between activates in such a way as to maximize benefits for a given budget. 

104
Identify opportunity cost
to spend resources on one activity means a sacrifice in terms of 
lost opportunity elsewhere 

105
Identify equity
fairness and justice in distribution of cost and benefits
106
3 reasons for prophlyaxis failure
Compliance, resistance, Interactions D+V
107
Malaria Dx Ix
GIEMSA thick and thin blood film
108
Malaria drug
artesunate
109
3 neuro signs lithium
coarse tremor, hyperreflexia, coma, ataxia, decreased conciousness, seizures
110
lithium teratogenicity
ebsteins - Cardiac
111
what is an advabced directive
An advance directive is a document by which a person makes provision for health care decisions in the event that, in the future, he/she becomes unable to make those decisions. 

112
Present with obstruction 4 immediate Mx IF STABLE(ish). 2 other to consdier
IV fluids NG tube + suction Catheter for urine output Analgesia Consider: Antibiotics Antiemetics (if vomiting)
113
1. Lady falls off her horse lands on left flank, now has blood in urine a. 4 immediate management ? b Imaging -? c. 3 other non-renal injuries to look out for? d. She is found to have grade 2 renal laceration, state what you would monitor and what is your management e. She is later discharged to GP, what advice would you give to GP on follow-up
U+E (Cr baseline), Analgesia, Lower limb neuro, clotting CT KUB Fracture – spine / pelvis, Ruptured spleen, Cord compression eg haematoma -> Cauda equina, pneumothorax all grade 1 and 2 and most grade 3 and 4 injuries, can be safely treated without active intervention. Monitor - Monitor U+E(Cr especially) , Urine output, BP / signs of shock Monitor renal function – if persists / gets worse to re admit
114
What is compartnemnt syndrome b. What is the most important symptom and most important sign that will make you suspect compartment syndrome What happens if left untreated ?
Bleeding into a closed space Increased pressure within one of the body’s anatomical compartments – leading to decreased blood supply of those tissues Sx - Pain out of proportion Sign - Pain on passive stretch ischemia, necrosis of muscle -> renal failure / amputation
115
4 mx of fracture
Conservative - Cast Internal fixation - intramedullary nail Open reduction internal fixation with plate Externa fixation
116
3. 50 year old man with viral conjunctivitis a. 4 symptoms that would aid in your diagnosis of viral conjunctivitis B 4 signs
Red eye, watery discharge, slight discomfort, burning senation Pre-auricular lymph nodes, conjunctival follicles, Lid oedema, acuity unaffected, normal pupil reponse
117
6. Some guy found in the park, he appears to be breathing, GCS of 9/15. No evidence of alcohol or dug use a. What are 4 initial management steps on taking over care of patient? b - Deteriorates to GCS 7/15 4 Mx now
ABCDE, Glucose, ECG, Examine for head injury Contact ICU, Secure Airway / provide O2, CT head, ABG
118
7. 20 year old girl has central abdominal pain, which then migrates to right iliac fossa, you suspect acute appendicitis. Her last period ended 3 days ago. a. What 2 physical signs would help you in your diagnosis b. What 2 common laboratory investigations would help you in your diagnosis c - 2 other Dx d. She then complains that pain is now widespread across abdomen and looks unwell, what 2 immediate actions would you take
Rosvigs, the psoas test, rebound tenderness CRP, WCC Renal colic, ovarian torsion, ovarian cyst Contact theatres, group and save (Antibiotics and fluid)
119
What is selction bias
Systematic error either: in the selection of participants; or, In the allocation of participants to different study groups
120
8 blood tests for dementia
FBC, ESR, U&E, TFTs, Glucose, Lipids, Calcium & B12, syphilis
121
3 aspects of initial management of dementia
[Higher functioning, cognition, memory ] refer to a memory assessment service treat any risk factors for cognitive impairment Patient education
122
2 causes for acute deteriation in dementia
Vascular - stepwise | Delerium - UTI / other causes
123
Mallory weiss mech
Excessive wretching / vomiting -> laceration of mucosa at junction of stomach / oesophagus
124
Stressed - over use meds and tension headaches Make a 4 point management plan to ensure holistic care organisational changes?
IAPT Address stress, relaxation techniques Exercise When / how much to use meds - don't overdo -> overuse headache Increased GP follow up Shorter prescription time
125
4 features of Delerium tremens
seizures, agitation, sweating, fever, hallucinations, tremor
126
2 questions to ask self for capacity assessment
Is there an impairment in their cognition | Is the patient unable to make a decision Understand, retain, weigh up, communicate
127
Anaphylaxis antihistamine you can never quite get right
chlorphenamine
128
1 blood test for anaphylaxis Dx
Mast cell triptase
129
Anaphylaxis pathophys
histamine mediated T1 HS reaction with mast cell degranulation
130
4 locations of endometriosis
lungs, ovaries, pouch of douglas, umbilicus
131
Management of endometreosis
COCP mirena tranexamic acid + mefanamic acid Gosrelin Ablation Hysterectomy
132
2 Mx acromegaly
Transphenoidal surgery – removal | Octreotide – somatostatin analogue
133
Surgical safety 4x pre-procedure checks 2x post-procedure checks 2x actions on incorrect swab count 2x DVT prophylaxis
Patient identifying features, consent form, do you have your own teeth? Patient knows purpose of operation? Site of operations/specifics, previous exposure to anaesthetics, allergies, anticipated blood loss, GS + crossmatch completed fluid balance, specimens for culture, equipment check – retained products, completion of anaesthetic chart, pain relief prescribed, anti-emetics prescribed re-count, re-open patient as never event (check floor, check operating table etc TED, LMWH, early mobilisation, good hydration
134
diagnose DIC from blood results
low plts, low fibrinogen, high aPTT, high PT, high thrombin time, high D dimer
135
DIC blood products to transfuse (no RBCs)
platelets cryoprecipitate - fibrinogen FFP - clotting factors
136
Bone marrow aspirate of AML
blast cells of myeloid precursors >20% Hypercellularity Auer rods
137
When not to give bulk-forming laxatives
in opioid constipation | [lactulose - like post hernia]
138
2 drugs for miss carriage
Anti-D, misoprostol
139
Abx for pyelonephritis , length?
Cipro IV 48hrs - review to step down for oral to complete 7 days
140
Grading of liver failure
child pugh ``` [Album encephalopathy bilirubin ascites INR ] ```
141
AKI stages
compare to Cr baseline: x1.5 - stage 1 x 2 - stage 2 x 3 - stage 3 (or over 354)
142
eGFR when not to use
doesn't work for extremes of age or weight Not applicable to AKI Cr clearance is more specific
143
bullus pemphigoid describe rash 2 comps Dx Mx
tense fluid-filled blisters on the trunk and limbs Erythematous - some burst? Size Antigens in epidermis Infection Complications of treatment Skin biopsy Serum autoantibodies High dose steroids, immunosuppression
144
Pemphigus vulgaris describe
Rash with flaccid eaisy ruptured blistered with erosions and crusts MUCOSAL involvement
145
Transfer co-efficient in asthma
normal / Increase
146
Decrease cause of transfer coefficient
``` Affects alveolar surface area COPD Anaemia Heart failure PE Fibrosis ```
147
Increase transfe coeffecicent
polycythemia | Asthma - maybe
148
2 interventions for food debis in oesophagus
capsule of Creon dissolved in 30 mL coke Endoscopic retreval
149
Addisons crisis 2 cat ions and 1 wcc Q2: 3 initial management points
hyperK, HypoNa, Eosinophilia ABCDE, IV fluid, IV hydrocortisone, O2 Don’t need fludrocortisone as high doses hydrocorsitone have mineralcorticoid effects
150
synacth test explain
Initial cortisol / give synacth IM – wait 30 mins – if cortisol rises = exclude addisons
151
Full term baby which deteriorated gradually over a few months. Turns out that she has an a severe genetic disorder. Parents want her to try on an experimental treatment. Her medical team has applied to the family division of the high court to withdraw life support. Q1: What 3 things would you like to ask the medical team and/or family about the patient’s condition and treatment before deciding on a course of action? Q2: 2 ethical principles when the medical team and the family disagree over the treatment of an infant. Q3: If the patient was an adult who wanted to try out a novel treatment and the medical team was supporting him, would you grant him wish? Use an ethical principle/existing legislation to explain your answer. Q4: Using deontology, explain the doctors decision to withdraw care for this baby
Suffering with treatment ? Benefits / evidence base of treatment? Cost of treatment ? Beneficence Non maleficicence Yes capacity and autonomy Based on action itself not consequences If give treatment – prolong unnecessary suffering
152
What is utalitarism ?
Ultaritarism – outcome (term is near enough synonymous with consequentialism)
153
5. Young gentleman injuries his right leg while playing football. It is painful and he has already received gas and air while in the ambulance. Leg deformed, but no open wound Q1: How else can you control his pain?
Boxplint | IV morphone
154
3 other benefits of a ‘box splint’.
less pain immobilise injury decrease swelling Helps maintain neurovascular status
155
Post cast compartment - 2 ways to have prevented
backslab instead of cast | reduce early
156
Q1: Genetic inheritance of sickle cell disease Q2: Symptoms of chest crisis. What is your initial management Q3: Why does he get gallstones Q4: What are other treatment would you offer alongside a routine cholecystectomy to reduce the likelihood of post op crisis. Q5: Has lots of painful crises What medications do you give and mechanism
AR HbS O2, iv fluids, pain relief, warmth, Abx Increeased haemolysis -> increased bilirubin -> gallstones RBC transfusion Hydroxycarbamide -> increases foetal Hb / less HbS production / less platlet Penicillin -> less infection -> less crisis
157
MCA
``` Assume capacity help them make decisions allow to make unwise decision Best interests Least restrictive option ``` [assume helping interesting, restricted, unwise decisions]
158
Why measure lactate in sepsis
Prognostic indicator and marker of anaerobic resp | monitor improvement
159
Chronic HF mx
Acei, Bblocker Furosemide - Sx Spirolactolone
160
Q1: 4 questions to assess the general fitness of a patient for surgery/anaesthetic
Weight, CVD, exercise tolerance, lung disease
161
ASA scores
``` 1 – healthy 2 – mild disease (doesn’t impact ) 3 – disease severe -/ impacts =====this is her 4 – incapacitating disease 5 – not expected to survive ```
162
Q3: How do you predict a difficult intubation? (3)
anaesthetic record Lack of neck extension Lack of jaw opening Malampati score
163
Q4: What from the WHO checklist do you do once the patient has arrived for surgery before anaesthetic (4)
``` Confirm patient Confirm procedure Any allergies Team brief Recovery location Equipment check Confirm consent Medications taken this morning / NBM Are you diabetic ```
164
Venous occlusion in eye what do you see
Flame hemorrages cotton wool spots Tortuous veins
165
MRSA Mx
Vanc
166
3 mechanisms of shoulder injury and how to manage
Rotator cuff tear – immobilise Dislocation – reduce and XR to make sure in right place Fracture – reduce and immobilise
167
Q3. 2 blood tests for someone with palpitations + what are you looking for?
TFT - hyper U+E – CA / K FBC - anaemia Catecholamines – phaeo
168
SVT Mx steps
``` vagal manoeuvres Adenosine Bblockers amiodarone shock ``` [can go adenosine -> shock if unstable]
169
Why hyperacusis in facial nerve palsy
Paralysis of stapedius
170
4 routes and drug for analgesia
i) Oral – paracetamol ii) IV – morphine iii) Inhaled -nos iv) Intranasal - fentanyl Sub cut - fentanyl
171
Parkland formula
4 x kg x %burn ½ in first 8hrs ½ over next 16hr
172
How thick should endometrium be post menopausal mx if CT Pelvis - stage 3 disease Q4. Which treatment / combination of treatments is best?
in post menopausal <5mm (or <8mm if receiving HRT) TAH + BSO + LN clearance + chemo if stage 3
173
Nephrotic syndrome Dx? In children?
3.5g protein / 24 hrs [in children is 1g] Oedema Hypoalbumin <30g/dL [<25 in children]
174
Lymphoma classification? staging?
WHO | Ann arbour
175
5 tests for haematuria
Dip, u+E, urinalysis, PSA, Autoantibodies, clotting | US KUB, MC + S
176
Leigonella mx
fluoroquinolone + clarithromycin
177
4 ways to gilick competency
he young person will understand the professional's advice; the young person cannot be persuaded to inform their parents; the young person is likely to begin, or to continue having, sexual intercourse with or without contraceptive treatment; unless the young person receives contraceptive treatment, their physical or mental health, or both, are likely to suffer; the young person's best interests require them to receive contraceptive advice or treatment with or without parental consent.
178
2 classes of drug to improve prognosis angina
statin – simvastatin, | Aspirin- Antiplatelet - cox 2 inhibitor
179
d) What is the area that connects a tendon/ligament to a bone? e) What is the name given to inflammation of an entire digit?
Enthesis Dactylitis
180
f) What anatomical area is inflamed in the joints of an inflammatory arthritis?
Synovium
181
ann arbour staging
1 – 1 node, 2 -2 nodes same side of diaphragm, 3 both sides, 4 wide spread and other organs
182
Mx of lymphoma in remission who have relapse
Peripheral stem cell transplant
183
Cushings b. GP sends her to endocrinologist - which 2 tests would confirm suspicion of Cushing’s syndrome c. Which test would tell you location of lesion?[not imaging] The above test comes back with low levels of analyte, what is your next choice of investigation Imaging to confirm
24hr urinary cortisol, dexamethasone suppression test Plasma - ACTH High dose dexamethasone still If high ACTH still - lung, low = pit – Chest/abdo CT Pit MRI
184
2 ECG Angina
ST depression and T wave inversion/flattening
185
3 Areas of HELLP mX
Deliver baby MgSO4 - prevent seizures IV steroids Mange BP if raised
186
How is audiogram carried out
sound proof room, headphones, sounds of variable vol and pitch in one ear, press button when hear it
187
What is a tympanogram
graphic representation of the relationship between the air pressure in the ear canal and the movement of the eardrum,