Pastest - PSYCHIATRY Flashcards

(170 cards)

1
Q

What are the objective signs of opioid withdrawal?

A

dilated pupils, yawning, rhinorrhoea (nose running), eiphoria (eyes watering)

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2
Q

Which med is used to treat hypersalivation in clozapine-treated patients?

A

hyoscine

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3
Q

A 60-year-old male is admitted to the in-patient psychiatric unit last night. On reviewing him this morning, he is a poor historian, answering most questions minimally and stating he does not need to be here as he is deceased, and hospitals should be for living patients.

What is the name of this delusional disorder and which condition is it most commonly associated with?

A

Cotard syndrome and major depressive disorder

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4
Q

You have been asked to review a patient with chest pain awaiting assessment by the psychiatry team.

Examination and investigations are normal, however, you note that he is acting strangely. He is reluctant to answer questions and does not maintain eye contact. After developing trust with him, he discloses he has never been in a relationship and that he prefers to be on his own as he won’t embarrass himself. He has no friends and doesn’t speak to his family because they criticise everything he does.

Which form of personality disorder is he likely suffering from?

A

Avoidant

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5
Q

A 29-year-old man is on the psychiatric ward under section 2 of the mental health act for suspected schizophrenia. He has a 3-month history of increasing suspicion of his family and had recently begun to collect weapons to defend himself. He started olanzapine 2 weeks ago. He has no other medical conditions and takes no other medications.

Today staff on the ward raised concerns due to his abnormal behaviour. He was found in his room sat on the floor with his back arched and legs hunched upwards. It is reported that he has been like this for the last 2 hours. His observations are normal. He has not spoken or made any movements during this time.

Which of the following best describes his current presentation?

A

Catatonia = stopping of voluntary movement or staying still in an unusual position

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6
Q

A 64-year-old male who has been on long term chlorpromazine presents with repetitive eye blinking. He reports he is unable to control this and is worried about what might be causing it. He is otherwise well in himself and has no visual disturbance. He has a normal facial and ocular examination with the exception of excessive rapid blinking.

What is the most likely cause of his symptoms?

A

tardive dyskinesia: can present as chewing, jaw pouting or excessive blinking due to late onset abnormal involuntary choreoathetoid movements in patients on conventional antipsychotics

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7
Q

A 23-year-old man presents to the emergency department following a recent diagnosis of migraine by his GP. He describes the headaches as right-sided, lasting around 6 hours, and brought on by work stress. He often feels nauseated with the headaches which resolve when he lies in a quiet room. He has a past history of depression and takes sertraline. He has no allergies. Neurological examination is unremarkable. The doctor reviewing him is concerned about a medication he has started for his symptoms.

What is the medication that the doctor is most likely to be concerned about in this patient?
Options:
1. ibuprofen and omeprazole
2. metoclopramide
3. paracetamol
4. prochlorperazine
5. sumatriptan

A

sumatriptan - triptans should be avoided in patients taking a SSRI

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8
Q

when does delirium tremens tend to occur?

A

48-72 hours after acute alcohol withdrawal

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9
Q

what is the most appropriate next step in management of more severe OCD which is unresponsive to CBT/exposure and response prevention?

A

Add an SSRI eg sertraline or fluoxetine

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10
Q

What is dialectical behaviour therapy (DBT) and when is it indicated?

A

focuses primarily on emotional regulation and is predominantly used in patients with emotionally unstable personality disorder (EUPD)

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11
Q

What is EMDR and when is it indicated?

A

eye movement desensitisation and reprocessing
predominantly used in PTSD

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12
Q

What type of urinary incontinence is the most associated with amitriptyline?

A

overflow incontinence - associated with tricyclic antidepressants

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13
Q

What are confabulations?

A

fabrications of imaginary experiences due to loss of memory - common phenomenon in patients with significant cognitive impairment eg dementia

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14
Q

A patient presents with complaints of involuntary muscle movements of her tongue, fingers and trunk for the past 2 months. She was diagnosed with schizophrenia 5 years ago and has been on flupenthixol and the haloperidol with good compliance. There is pronounced choreoathetoid movement. What is the next line of management of this patient?

A

stop the haloperidol and start olanzapine

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15
Q

which axis is involved in the pathophysiology of anxiety disorders, panic disorder and PTSD…?

A

hypothalamic pituitary adrenal axis (HPA)

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16
Q

Which Questionnaire is used to monitor response to treatment in patients with depression?

A

patient health questionnaire (PHQ-9)

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17
Q

What is schizoid personality disorder?>

A

disorder where patient has a long history of loneliness, odd behaviours and flat affects
they do not have any weird/magical thinking (schizotypal) or psychotic symptoms (schizophrenia, schizoaffective disorder)

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18
Q

which blood investigations can be used for assessing alcohol intake?

A

mean corpuscular volume
LFTs
gamma glutamyl transferase

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19
Q

what is the level for lithium toxicity?

A

levels above 1.5 mmol/l

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20
Q

what is the mechanism of action of duloxetine?

A

serotonin and noradrenaline reuptake inhibitor

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21
Q

what is used to treat delirium tremens/alcohol withdrawal?

A

chlordiazepoxide or diazepam

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22
Q

what are the criteria in ICD-10 for mania?

A

elated mood/occasional irritability
increased energy
psychotic symptoms (?)
to diagnose need at least 3 of DIGFAST:
D – distractibility/inability to sustain attention
I – indiscretions/impulsivity/loss of social inhibitions/aggression (excessive pleasurable activities, risky sexual behaviour, drug taking, fast driving)
G – grandiosity (mood congruent – as elated)/extravagance
F – flight of ideas– difficult to interpret
A – activity increase/excessive optimism
S – sleep deficits/decreased need for sleep
T – talkativeness/pressure of speech

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23
Q

what is hypomania according to ICD-10?

A

lesser degree of mania but too persistent and marked to be cyclothymia
features:
elated mood, increased energy and activity
Feeling of mental and physical wellbeing and efficiency
Increased sociability, overfamiliarity, sexual drive
Decreased need for sleep
Irritability
NO PSYCHOTIC SYMPTOMS, OR DISRUPT TO WORK/SOCIAL ACTIVITIES

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24
Q

What is the difference between hypomania and mania?

A

hypomania has no psychotic symptoms and it does not disrupt work/social activities

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25
What medication is good to use for children or adults with learning difficulties who have irregular natural sleep-wake cycles?
melatonin
26
What are some of the sudden discontinuation symptoms from abruptly stopping SSRIs?
rebound anxiety or depressive symptoms, flu-like symptoms, dizziness, nausea or sleep disturbances
27
When is EMDR (eye movement desensitisation and reprocessing) not used in PTSD? What would be used instead?
EMDR is recommended treatment of PTSD, except in the case of combat-related trauma - instead trauma-focused CBT would be used
28
A 19 year old woman presents to her GP with a 3 year history of restricting food intake and self-induced vomiting. She attends her GP for the first time with her sibling reporting a recent worsening of her symptoms. The GP suspects anorexia nervosa. What is the most appropriate investigation to determine whether the patient requires urgent hospital admission?
ECG for any cardiovascular instability, including assessment of HR, along with assessment of the QT interval
29
What is factitious disorder?
refers to a patient with no physical or organic disease but who finds satisfaction in taking on the 'sick role' and wants to be taken care of
30
What is factitious or induced illness?
similar to factitious disorder but involves a patient seeking the 'sick role' vicariously through a second patient *think about the film 'the act' where the mother suffering from factitious disorder will abuse her child so that she can bring the child to the doctor for treatment
31
What is conversion disorder?
refers to manifestation of psychological illness or neurologic pathology. These patients suffer from weakness, numbness, blindness or paralysis as symptoms of an underlying psychiatric illness
32
What is zopiclone used for?
used as a hypnotic to help people sleep.
33
An 18 year old male student spontaneously disrobed while watching a film. He saw wavy lines on the screen and then reported a brief episode of mental blankness, followed soon after by a headache and extreme fatigue. What is the most likely diagnosis?
Partial complex seizure or Focal Impaired Awareness epilepsy
34
What needs to be monitored when giving a patient Clozapine?
there is up to 2% risk of developing agranulocytosis (lowered WBC) therefore WBC should be monitored clozapine can cause bone marrow suppression leading to lowered WBC count and increasing the risk of infection in these patients
35
A 50 year old woman is brought in by her son because she is acting 'wild' again. She drinks moderately about once a week. She is not sleeping much, talks incessantly about plans to read the great books and has made many impulsive and irrational purchases. She reports hearing voices but refuses to discuss this issue when questioned by the admitting psychiatrist. She begins a task but does not complete it, all the while making lists of things to be done. She has been starting tasks and not finishing them. She had a similar episode 4 years ago. She also has depressive episodes several times over the last few years and recovered in between them. What is the most likely underlying diagnosis?
bipolar, manic, with mood-congruent psychotic features
36
What is schizophreniform disorder?
symptoms of schizophrenia of <6 months duration
37
What is schizoaffective disorder? Which patients are excluded from this diagnosis?
Features of both schizophrenia and affective disorder (e.g. depression, mania, mixed), present in approx. equal proportion - lasting considerable part of at least 1 month Exclude patients: With separate episodes of SZP or mood disorders; In the context of substance use or other medical disorder (organic cause)
38
What is the term for the repetition of someone's speech?
echolalia
39
What is the difference between knight's move and flight of ideas?
Knight's move thinking there are illogical leaps from one idea to another, flight of ideas there are discernible links between ideas
40
A 20 y.o. first time mother presents with severe weight loss, anorexia and believes that her husband is interested in killing her and their baby son and feels completely worthless. What is the single most appropriate treatment option? Clozapine CBT fluoxetine lithium monitor at home
fluoxetine
41
A 40 y.o. man has been treated for depression for 3 months. He is now beginning to lose weight and getting suicidal thoughts more frequently than before. What is the single most appropriate treatment option? ECT flupnethixol no action psychodynamic psychotherapy sertraline
sertraline
42
A 29 y.o. woman presents with new-onset inability to sleep, excessive spending and increased libido. What is the single most appropriate treatment option? behavioural activation citalopram counselling quetiapine ECT
quetiapine
43
An 18 y.o. girl with a BMI of 15 complains of three month history of amenorrhoea. She is not on the pill and the pregnancy test is negative. She wants to be a model. What is the single most appropriate next step in management? assess physical state citalopram food diary olanzapine supplement drinks
assess physical state
44
A 20 y.o. man keeps cleaning his hands every time he shakes his partner's hands. He was a high achiever in high school. What is the single most likely diagnosis? anakastic personality disorder borderline personality disorder dependent personality disorder avoidant personality disorder schizoid personality disorder
anakastic personality disorder
45
what is anankastic personality disorder?
another term for obsessive compulsive personality disorder
46
A 56 y.o. farmer believes that his neighbour is killing his farm animals despite the local veterinary's advice that the death is due to an outbreak of anthrax. He spends hours watching his neighbour through pair of binoculars, hoping to catch him in the act. What is the single most likely diagnosis? anankastic personality disorder borderline personality disorder histrionic personality disorder paranoid personality disorder schizotypal personality disorder
paranoid personality disorder
47
A 23 y.o. student presents with insomnia, headaches, sweating, palpitations, chest pain and poor appetite. What is the single most likely diagnosis? alcohol dependency generalised anxiety disorder schizophrenia social phobia somatisation disorder
generalised anxiety disorder
48
A 35 y.o. single woman presents with a 3 month history of weight loss, poor appetite, decreased ability to concentrate and guilt feelings. What is the single most likely diagnosis? depression hypomania obsessive compulsive disorder post-traumatic stress disorder schizophrenia
depression
49
A 19 y.o. female student was at her fathers funeral last week. She presents with sudden onset of blindness. Neurologic examination reveals no abnormality. What is the single most likely diagnosis? conversion disorder depersonalisation hypochondrial disorder obsessive compulsive disorder schizophrenia
conversion disorder
50
A 20 y.o. man presents with disinhibition, hyperactivity, increased appetite and grandiose delusions over the past 2 weeks. What is the single most likely diagnosis? adjustment disorder ADHD depressive episode mania schizophrenia
mania
51
What does disinhibition mean?
can be defined as the inability to withhold a prepotent response or suppress an inappropriate or unwanted behaviour. It can refer to the production of socially inappropriate comments and/or actions
52
A 31 y.o. man presents with auditory hallucinations, social withdrawal and delusions of persecution. What is the single most likely diagnosis? alcohol dependency bipolar affective disorder depersonalisation paranoid schizophrenia persistent delusional disorder
paranoid schizophrenia
53
A 22 y.o. man presents with compulsions and rituals, which he attempts to resist, but he is unable to do so. What is the single most likely diagnosis? depersonalisation dissociative disorder obsessive compulsive disorder post-traumatic stress disorder schizophrenia
obsessive compulsive disorder
54
A 71 year old retired engineer experiences changes in personality and impaired social skills. His family, who describe him as forgetful and not as sharp, corroborates this. There are no objective features of depression. What is the single most likely diagnosis? adjustment disorder fronto-temporal dementia late onset schizophrenia panic attacks social phobia
fronto-temporal dementia
55
A 20 y.o. man is noted to be withdrawn, isolated and peculiar. He has persecutory beliefs gangsters are out to get him and says he hears them talking about him, when no one else can hear them. What is the single most likely diagnosis? delirium depression with psychotic symptoms hypomania panic disorder paranoid schizophrenia
paranoid schizophrenia
56
An 80 y.o. widow is noted by her family, over the past 3 months, to be restless and often crying. She frequently says she wants to die. What is the single most likely diagnosis? alcohol dependence Alzheimers dementia delirium depression generalised anxiety disorder
depression
57
A 40 y.o. cyclist complains of frequent episodes of chest pains, sweating, palpitations, a sense of impending doom and trembling that lasts for minutes at a time. What is the single most likely diagnosis? angina generalised anxiety disorder hypochondrial disorder panic disorder social anxiety disorder
panic disorder
58
A 25 y.o. man presents with miosis, slurred speech, disorientation, and respiratory depression. What is the single most likely diagnosis? alcohol intoxication amphetamine overdose opiate overdose paracetamol overdose
opiate overdose
59
A 70 y.o. man presents with progressive forgetfulness and mood changes. He has a shuffling gait and visual hallucinations at night. These have been present for 1 year. The head CT scans shows cortical atrophy and enlarged ventricles. What is the single most appropriate treatment option? co-beneldopa diazepam procyclidine risperidone rivastigmine
rivastigmine
60
A 60 y.o. man presents with a disturbance of voluntary motor function. His face is expressionless. On examination he has cogwheel rigidity and bradykinesia. He has no cognitive impairment. What is the single most appropriate treatment option? co-beneldopa diazepam procyclidine risperidone rivastigmine
co-beneldopa
61
A 40 y.o. accountant presents with acute confusion. He is seeing spiders crawling on his arms and has a broad based gait on physical examination. What is the single most appropriate treatment option? acamprosate chlordiazepoxide diazepam disulfiram pabrinex
pabrinex
62
what is in pabrinex and what is it used for?
Thiamine and ascorbic acid used for treatment of suspected or established Wernicke's encephalopathy
63
A 23 y.o. female presents with constant low mood and irritability. She thinks regularly about suicide. She has trouble sleeping and has lost her appetite. Her father died four weeks ago. What is the single most likely diagnosis? abnormal grief reaction adjustment disorder depressive disorder dysthymia PTSD
abnormal grief reaction
64
A 30 y.o. female complains of depression, lethargy, constipation, and weight gain. She also suffers from menorrhagia. What is the single most likely diagnosis? alcohol abuse bipolar affective disorder bulimia nervosa hypochondrial disorder hypothyroidism
hypothyroidism
65
A 40 y.o. woman presents with depression and weight gain. She complains of back pain and excessive thirst. Her menstrual period lasts for three days and sometimes she skips a cycle. On examination she is obese with acne and peripheral oedema. What is the single most likely diagnosis? Addison's disease Cushing's syndrome hyperparathyroidism porphyria recurrent depressive disorder
Cushing's syndrome
66
A 30 y.o. female on the OCP presents with colicky abdominal pain, vomiting, and depression. She is noted to be hypertensive. She reports that her urine turns deep red if left to stand during these episodes. What is the single most likely diagnosis? Cushing's syndrome drug abuse hyperthyroidism hypothyroidism porphyria
porphyria
67
A 33 y.o. female presents to the GP with chronic feelings of isolation and hopelessness. She struggles to maintain relationships and finds the only effective coping method to relieve her distress is to make superficial cuts to her forearm. What is the single most likely diagnosis? anankastic personality disorder borderline personality disorder dependent personality disorder histrionic personality disorder narcississtic personality disorder
borderline personality disorder
68
A 42 y.o. man insists that his wife is unfaithful and sleeping with most of the local neighbourhood. He is hypersensitive, argumentative and litigious. His wife has left him due to his behaviour. He functions well at work. What is the single most likely diagnosis? Capgras syndrome Cotards syndrome De Clerambault syndrome Foliea deux Othello syndrome
Othello syndrome
69
A 26 y.o. woman presents with irritability and insomnia for the past 3 weeks. 2 years ago she had severe depression with low self-esteem and suicidal thoughts. When she is interviewed, she presents with pressured speech. What is the single most likely diagnosis? bipolar affective disorder delusional disorder paranoid schizophrenia recurrent depressive disorder
bipolar affective disorder
70
A 20 y.o. woman feels that she has no need for sleep. She has reached her credit card limit on recent shopping spree. Her appetite is unaffected. She has no psychotic symptoms. She continues to work in her job as a receptionist. What is the single most likely diagnosis? amphetamine use bipolar affective disorder hypomania meningioma schizoaffective disorder
hypomania
71
A 20 y.o. woman presents to her GP complaining of feeling depressed ever since she can remember. She sees herself as a failure but functions well at work. She has trouble falling sleep. What is the single most likely diagnosis? body dysmorphic disorder dysthymia generalised anxiety disorder paranoid schizophrenia recurrent depressive disorder
dysthymia
72
A 19 y.o. man presents with nausea, vomiting and sweating. His pupils are dilated and his BP is elevated. He has a history of drug addiction. What is the single most likely diagnosis? alcohol intoxication alcohol withdrawal cannabis intoxication cocaine intoxication opioid withdrawal
cocaine intoxication
73
A 30 y.o. woman is found in an amnesic state. Her sister reports that she had been missing for a few days after she has been served with divorce papers. What is the single most likely diagnosis? alcohol intoxication alcohol withdrawal delirium dementia dissociative fugue
dissociative fugue
74
A 30 y.o. man with bipolar disorder is taking lithium. He was recently started on thiazide diuretics for mild hypertension. He is now confused with ataxia, blurred vision and a coarse tremor. What is the single most likely diagnosis? alcohol withdrawal lithium toxicity opioid withdrawal renal failure thyrotoxicosis
lithium toxicity
75
Which class of drug have the Medicines and Healthcare products Regulatory Agency warned may be associated with an increased risk of venous thromboembolism in elderly patients?
atypical antipsychotics - in the elderly has increased risk of stroke and VTE
76
What are some examples of atypical antipsychotics?
clozapine, risperidone, olanzappine
77
what are some examples of typical antipsychotics?
haloperidol and chlopromazine
78
What is one symptom or sign that may be exhibited on withdrawal of heroin for the following categories: neurological, psychological, gastrointestinal and dermatological?
neurological: agitation, paraesthesia and dilated pupils psychological: depression, craving gastrointestinal: diarrhoea, vomiting, abdominal cramps dermatological: sweating, 'goose bumps'
79
the long-term use of which of the following causes hyperparathyroidism and resultant hypercalcaemia? amitriptyline clozapine lithium sertraline sodium valproate
lithium
80
A 45 y.o. man describes successful abstinence from alcohol for the past six months following inpatient detoxification. During his admission, he was started on a 'deterrent' medication. He takes this medication daily and reports that if he consumes alcohol he will 'violently vomit'. Which medication is the patient describing?
Disulfiram - with alcohol induces facial flushing, nausea and vomiting. Disulfiram is used as a deterrent to prevent alcohol relapse
81
A 45 y.o man describes successful abstinence from alcohol for the past six months following inpatient detoxification. During his admission, he was prescribed an 'anti-craving' medication. He takes this medication three times a day and would like you to continue the prescription as he finds it very helpful. It is safe in combination with alcohol and he has experienced no side effects. Which medication is he describing?
Acamprosate - effective in preventing alcohol relapse in combination with psychological support following detoxification in alcohol dependence syndrome It has a minimal side effect and risk profile and is safe in combination with alcohol
82
A 38 y.o. man presents with opioid dependence syndrome presents to clinic. He currently takes 30ml of methadone daily. He wishes to come off of his methadone as he finds it too sedating and is finding the stigma of being on methadone challenging. He reports friends have successfully come off methadone after stitching to a 'tablet that goes under your tongue' and wishes to try this. Which medication is the patient describing?
Buprenorphine - this is a mixed opioid agonist/antagonist. It is typically given as a sublingual tablet and provides an alternative opiate replacement therapy to methadone Patient's often describe beprenorphine as less sedating
83
what is something that prescribers should keep in mind when administering methadone?
prescribers must be aware that because of the opioid antagonist properties of methadone, it can render regularly prescribed analgesia, such as co-codamol, ineffective
84
What is chlordiazepoxide and when is it used?
it is a benzodiazepine often used as part of a reducing regime during alcohol dependence
85
On examination, the patient appears unkempt. When asked how they are, the patient replies 'I'm fine, like sweet wine, the pleasure is mine'. What best describes this behaviour?
clang associations
86
What is cluster B personality and what are the types?
Cluster B traits include being dramatic and overly emotional, unpredictable thinking, and/or behaviour associated with the above. Cluster B includes antisocial personality disorder, borderline personality disorder, histrionic personality disorder, and narcissistic personality disorder.
87
What is Korsakoff's syndrome?
a complication of Wernicke's encephalopathy. It's features include: anterograde amnesia, retrograde amnesia, and confabulation
88
What is the classic triad of Wernicke's encephalopathy?
ophthalmoplegia (often a lateral rectus palsy and/or horizontal nystagmus), confusion and ataxia (though any cerebellar signs can be present)
89
What is akathisia?
a sense of inner restlessness and inability to keep still - typical with a long history of anti-psychotic use
90
What are the metabolic side effects of antipsychotics?
dysglycaemia, dyslipidaemia, and diabetes
91
What is the first-line treatment for children and young people with anorexia nervosa?
anorexia focused family therapy
92
A 30 y.o. man with bipolar disorder is taking lithium. He was recently started on thiazide diuretics for mild hypertension. He is now confused with ataxia, blurred vision and a coarse tremor. What is the single most likely diagnosis? Alcohol withdrawal Lithium toxicity Opioid withdrawal Renal failure Thyrotoxicosis
Lithium toxicity
93
A 50 y.o. man with a history of schizophrenia is started on haloperidol. A month later he is noted to be stiff and complains of tremor in both arms. What is the single most likely diagnosis? Cushing's syndrome Extra-pyramidal side-effects Neuroleptic malignant syndrome Parkinson's disease Tardive dyskinesia
Tardive dyskinesia
94
A 40 y.o. female complains of dry mouth, blurry vision, and constipation. On examination she had dilated pupils. She was started on amitriptyline for major depression. What is the single most likely diagnosis? Anticholinergic side effects Extra-pyramidal side effects Neuroleptic Malignant syndrome Noradrenergic side-effect Serotonin syndrome
Anticholinergic side effects
95
A 30 y.o. man with history of psychosis presents to casualty saying he has a dislocated shoulder. On examination, the shoulder is found not to be dislocated. The patient insists it is dislocated and will not accept reassurance from the doctors. What is the single most likely diagnosis? Delusional disorder Dissociative disorder Hypochondriacal disorder Panic disorder Somatisation
Delusional disorder Hypochondriacs can entertain the possibility that the feared disease is not present. In contrast, people with somatic-type delusional disorder are completely convinced of the physical basis of their complaints.
96
A 28 y.o. woman lost her job three months ago. She attends her GP complaining of difficulty in sleeping,. She feels tired, has a poor appetite and has lost some weight. She feels worthless. She has thought of committing suicide and says that her husband would not miss her if she were dead. What is the single most appropriate treatment option? Fluoxetine Lithium Mirtazapine Moclobemide Zopiclone
Fluoxetine
97
A 22 y.o. single woman gave birth to her first child three days ago. Since the birth she has been unable to sleep and is reluctant to hold her baby or feed her. She is very tearful and cries for no reason. She denies thoughts of harming the baby. What is the single most appropriate treatment option? Diazepam Fluoxetine Monitor Risperidone Zopiclone
Monitor
98
A 64 y.o. woman has a three year history of increasing confusion, loss of mobility and tremor. She has recently developed frequent visual hallucinations and tends to cry out for no reason, particularly at night. There is no evidence of an acute medical cause for her confusion. On examination she is alert but disorientated and quite agitated. She has a coarse resting tremor, increased tone in her limbs and normal reflexes. What is the single most appropriate treatment option? Fluoxetine Procyclidine Risperidone Rivastigmine Zopiclone
Rivastigmine
99
A mother is worried about her 25 y.o. son. He seems to jump from one topic to another, make up words, laugh at inappropriate things and talk to someone imaginary. He has blacked out his windows and complains that someone else is controlling his thoughts. What is the single most likely diagnosis? Alcohol intoxication Cannabis use Depression with psychotic symptoms Hypomania Paranoid schizophrenia
Paranoid schizophrenia
100
A 40 y.o. man presents to his GP with headaches, insomnia and weight gain. He is slow and sluggish when he speaks. He describes a loss of interest in everything, a feeling of worthlessness and often cries alone. What is the single most likely diagnosis? Adjustment disorder Depression Generalised anxiety disorder Hyperthyroidism Schizophrenia
Depression
101
Which eye condition is associated with Charles-Bonnet syndrome?
Age-related macular degeneration and cataracts Patients tend to have visual hallucinations, especially when it is dark, due to the inability to differentiate contrast sensitivity.
102
A 54 y.o. man attends his GP. He was started on fluoxetine eight weeks ago for depression and is now requesting to stop his medication as he feels so well. How long should his medication be continued for before he stop it completely?
it should be continued for at least 6 months after signs of remission this greatly reduces the risk of relapse and patients should be reassured that antidepressants are not addictive
103
Bulimia nervosa can have ECG signs of first-degree heart block, tall P waves and flattened T waves. It can also have metabolic alkalosis and low chloride. Why is this?
The patient's ECG shows features of hypokalaemia which is a likely cause of palpitations The low chloride suggest the cause of the metabolic alkalosis is loss of hydrochloric acid from the stomach (through vomiting). Severe vomiting would also account for the hypokalaemia shown on ECG
104
What is the mechanism of action of venlafaxine?
serotonin and noradrenaline reuptake inhibitor
105
With alcohol withdrawal, what is the timing for having the following presentations after the last drink? symptoms seizures delirium tremens
symptoms: 6-12 hours seizures: 36 hours delirium tremens: 72 hours
106
A 34 y.o. lady has presented to her GP for review of her medication. She was diagnosed with bipolar disorder 8 months previously and has been taking olanzapine 10mg once daily and lithium carbonate 600mg twice daily. She has noticed that her psychological symptoms have improved overall, however she reports feeling more tired in the past month. She also reports reduced appetite and with bouts of constipation. Given her presentation, what is the most likely explanation for her symptoms?
hypothyroidism due to lithium toxicity it usually manifests between 6-18 months after initiation of treatment
107
A 54 y.o. man with no past medical history is being started on tranylcypromine (a monoamine oxidase inhibitor) for depression. Which foods should he be advised to avoid?
cheese when tyramine containing food (eg cheese) are taken alongside monoamine oxidase inhibitors a hypertensive crisis can occur
108
A 45 y.o. man with schizophrenia taking chlorpromazine develops an oculogyric crisis. What side-effect of antipsychotic medication is this an example of?
Acute dystonia
109
What does taking an SSRI alongside an NSAID increase the risk of? What should be prescribed alongside these?
increases the risk of GI bleeding, therefore a PPI should be prescribed
110
What is a side effect of lorazepam relating to memory?
One of the side effects of this drug is that this can cause anterograde amnesia, where memory recall and the creation of new memories is significantly impaired.
111
A wife cannot cope with her husband's moods. She says he is very labile. He goes from being full of energy and happy one day to being so pessimistic about everything the next day. What is the single most likely diagnosis? bipolar affective disorder borderline personality disorder dependent personality disorder dysthymia generalised anxiety disorder
borderline personality disorder
112
A 56 year old woman says that she hears her recently deceased husband in and around the house. What is the single most appropriate treatment option? anti-depressive medication anti-psychotic therapy anxiolytic medication behavioural therapy bereavement counselling
bereavement counselling
113
A 19 year old female university student undertakes hand washing up to 20 times in one day; this is getting in the way of her work. What is the single most appropriate initial treatment option? benzodiazepines clomipramine CBT group therapy sertraline
CBT
114
A 60 y.o. homeless man who smells of alcohol is admitted to a medical ward after a fall. He is confused and says he thinks that the nurses are going to kill him. What is the single most appropriate course of action? arrange for urgent CT head scan detain under section 5(2) of the MHA prescribe chlordiazepoxide prescribe pabrinex undertake physical examination
undertake a physical examination
115
A 24 y.o. man says that he can hear a voice talking to him and it is controlling his thoughts. What is the single most appropriate treatment option? anti-depressant medication anti-psychotic medication behavioural therapy bereavement counselling electro-convulsive therapy
anti-psychotic medication
116
A 40 y.o. woman is scared of flying to the degree she will not fly at all. What is the single most appropriate option? anti-depressant medication benzodiazepine medication cognitive-behavioural therapy group therapy hypnotherapy
cognitive behavioural therapy
117
A mother brings her child to you in outpatients with chronic constipation. On physical exam you notice unusual bruising on both arms. What is the single most appropriate initial management option? arrange an abo X-ray inform child safeguarding team inform the police prescribe laxatives refer her child to a child psychiatrist
inform child safeguarding team
118
A 25 y.o. woman with a history of depression and self harm arrives at ED saying she has ingested an unknown amount of an unknown drug. What is the single most appropriate management option? begin N-acetyl cysteine therapy contact GP complete a physical health assessment refer to a psychiatrist refer to general medical team
complete a physical health assessment
119
A 30 y.o. man recently started on olanzapine presents with dizziness and irritability. In ED the patient behaves aggressively and abuses the nursing staff. On examination you find him to be febrile, and mild neck rigidity is present. What is the single most appropriate management option? admit to general medical ward increase his dose of olanzapine prescribe lorazepam refer to psychiatrist resuscitate in the department
resuscitate in the department
120
A 26 y.o. woman who used to be an IV drug user had completely stopped taking drugs. She comes to you saying that her boyfriend is now forcing her to take drugs again. She has noticeable bruising on her arms and legs. What is the single most appropriate management option? discuss with adult safeguarding team inform the police prescribe naloxone prescribe naltrexone refer to addiction services
discuss with adult safeguarding team
121
A 25 y.o. woman finds it difficult to leave her home. She becomes very agitated in supermarkets and describes palpitations and difficulty breathing when in crowds. What is the single most likely diagnosis? agoraphobia bipolar affective disorder generalised anxiety disorder PTSD social phobia
agoraphobia
122
A 40 y.o. man complains of low mood and fatigue. He has a poor appetite and has loss of libido. He wakes at 2am and is unable to return to sleep. He feels guilty about the death of his mother 2 years ago. What is the single most likely diagnosis? bipolar affective disorder depressive episode generalised anxiety disorder panic disorder social phobia
depressive episode
123
A 30 y.o. man is seen in dermatology outpatients with very sore hands. He has dry, cracked skin on all his fingers. He says he has to wash his hands at least 30 times a day and is unable to sleep if he has not done so. What is the single most likely diagnosis? delusional disorder generalised anxiety disorder hypochondriacal disorder obsessive compulsive disorder PTSD
obsessive compulsive disorder
124
A 20 y.o. woman attends A&E complaining of sudden breathlessness and anxiousness. She describes palpitations and pins and needles in her hands, feet and lips. Her ECG shows sinus tachycardia and oxygen saturation is normal. What is the most likely diagnosis? bipolar affective disorder depression hypochondriacal disorder panic attack social phobia
panic attack
125
A 36 y.o. train driver is on sick leave after an incident in which a child ran onto the tracks. He is unable to go near railways and takes excessively long routes to avoid them. He is troubled by flashbacks of the accident, which frequently disturbs his sleep. What is the single most likely diagnosis? generalised anxiety disorder hypochondriacal disorder obsessive compulsive disorder panic disorder PTSD
PTSD
126
A 76 y.o. man is agitated and euphoric. He claims to be helping the Prime Minister and the President of the United States with economic policy. He lives in sheltered accommodation. There are no signs or symptoms of physical illness. What is the single most likely diagnosis? alcohol withdrawal delirium dementia mania personality disorder
mania
127
A 20 y.o. man complains that all his movements are being watched. Sometimes he feels as though his actions are being controlled by his radio. At other time he is aware of voices describing what he is doing. What is the single most likely diagnosis? delirium Korsakoff's psychosis mania psychotic depression schizophrenia
schizophrenia
128
A 50 y.o. man presents in outpatients complaining of being pursued by the police for a crime he denies committing. He has poor concentration and impaired short term memory. He admits to drinking large amounts of alcohol. What is the single most likely diagnosis? Alzheimer's delusional disorder hypomania Korsakoff's psychosis Wernicke's encephalopathy
Korsakoff's psychosis
129
A 65 y.o. woman says that she died three moths ago and is very distressed that nobody has buried her. When she is outdoors she hears people say that she smells and needs to be punished. What is the single most likely diagnosis? Alzheimer's conversion disorder Cotard's syndrome Korsakoff's psychosis schizophrenia
Cotards syndrome
130
A 49 y.o. woman is recovering from a hysterectomy two days ago. She becomes agitated and complains of seeing animals and children walking around the wards. Her husband reports she drinks at least a bottle of wine per day. what is the single most appropriate treatment? ascorbic acid diazepam disulfiram haloperidol thiamine
thiamine
131
A 30 y.o. man slowly develops severe depression over a number of months. He stops his hobbies and interests, his social contact diminishes and his mood becomes very low. He visits a psychiatrist for the first time because he is becoming increasingly distressed with disturbed sleep patterns and no appetite. He feels his future is hopeless. What is the single most appropriate treatment option? amitriptyline citalopram mirtazapine olanzapine venlafaxine
citalopram
132
A 55 y.o. woman has episodes of mania associated with frequent depressive episodes. What is the single most appropriate treatment option? carbamazepine chlorpromazine clozapine lorazepam sodium valproate
sodium valproate - used to treat bipolar disorder
133
An 18 y.o. woman with no physical health problems is waiting for her A-level exam results. They will arrive by post today and she is suffering from acute anxiety due to the importance of these results for her future. Her mother consults her GP. What is the single most appropriate treatment option? CBT lorazepam practicing mindfulness techniques propanolol temazepam
practicing mindfulness techniques
134
A 87 y.o. woman moved in to a residential care home two weeks ago. She has a diagnosis of Alzheimer's disease and was started on donezepil six months ago. She has become agitated and wants to return to her own home. What is the single most appropriate option? admit to hospital under the mental capacity act admit to hospital under the mental health act investigate for an organic cause for this presentation organise an urgent CT head head scan prescribe risperidone
investigate for an organic cause for this presentation
135
A 32 y.o. man with history of depression and a previous attempt to end his life by hanging comes to ED. He says he is relapsing, feels hopeless, and cannot keep himself safe at home anymore. He says he wants help but cannot face going home. He has been taking his medication as prescribed. He asks to be admitted to hospital. What is the single most appropriate treatment option? admit as a voluntary patient detain under section 2 detain under section 3 detain under section 5(2) refer to intensive community support team
admit as a voluntary patient
136
A 90 y.o. man is admitted to a nursing home. He has a diagnosis of Alzheimer's disease but is on no medication. He becomes aggressive and starts urinating in waste bins. What is the single most appropriate treatment option? admit for psychiatric assessment exclude delirium organise a CT head scan prescribe donepezil prescribe olanzapine
exclude delirium
137
A 44 y.o. woman with a history of agoraphobia presents with an acute GI bleed. After recovery she is commenced on an antidepressant to help with her mental health disorder. What is the most likely drug that the psychiatrists will recommend is avoided? clomipramine fluoxetine mirtazapine risperidone venlafaxine
fluoxetine
138
A 42 y.o. man is brought to hospital by the police. they found him trying to stop traffic on the motorway saying the Lord was making him do it. The police reports thinks that he has a mental illness. He has not been seen by a doctor. What is the single most likely section the patient is detained under? section 2 section 5(2) section 62 section 135 section 136
section 136
139
A 61 y.o. man with a history of a traumatic head injury in a motorcycle accident presents with memory problems. He forgets to take his medication, is disorientated in time and is incontinent of urine. He walks as if he is intoxicated and needs a zimmer frame to mobilise safely. What is the single most likely diagnosis? Alzheimer's disease fronto-temporal dementia lewy body dementia neurosyphilis normal pressure hydrocephalus
normal pressure hydrocephalus
140
A 31 y.o. man has been diagnosed as suffering from schizophrenia. He is known to have a history of heavy recreational drug use starting in his teenage years. His psychiatrist tells him that the substance he uses may have contributed to him developing disorder. Which of the following drugs is the psychiatrist most likely to be referring to? alcohol cannabis cocaine heroin LSD
cannabis
141
A 39 y.o. woman is recovering from a hysterectomy three days ago. She dose not drink alcohol at all and dose not use recreational drugs. At night she becomes agitated and complains of seeing animals and children walking around the wards. What is the single most likely diagnosis? delirium dissociative disorder hypomania Korsakoff's psychosis schizophrenia
delirium
142
A 25 y.o. man is admitted to hospital after developing psychotic symptoms, including some which his psychiatrist describes as "first rank". Which of the following is the patient most likely to be suffering from as a first rank symptom? 2nd person auditory hallucinations 3rd person auditory hallucinations blunting of affect flight of ideas persecutory delusions
3rd person auditory hallucinations
143
A 19 y.o. Afro-Caribbean man, who has emigrated to London from Jamaica, develops psychotic symptoms. His father had been diagnosed with schizophrenia. Which statement best describes this mans risk of developing schizophrenia? about 50% higher than general population lower than general population same as general population unaffected when compared to general population unless he also smokes cannabis
higher than general population
144
A 78 year old man with a history of chronic schizophrenia presents to the ED with a three week history of worsening auditory hallucinations which have been accompanied by frightening visual hallucinations over the past three days. He has developed urinary incontinence over the past week. What is the most likely cause of his current symptoms? acute polymorphic psychosis delirium delirium tremens dementia schizophrenia
delirium
145
A man presents with persecutory delusions and third person auditory hallucinations. He is diagnosed with schizophrenia. He has no previous psychiatric history and no family history of mental health problems. From the information above, in what age range is this patient most likely to be? 18-30 years 30-40 years 40-50 years 50-60 years over 60 years
18-30 years
146
A diagram relates to a psychological model used to treat mental health disorders. Three domains have been replaced by letters A, B and C. These domains are related to negative automatic thoughts. What do these letters represent? conversion, dissociative and somatoform id, ego, superego physical sensations, emotions, behaviours repression, regression and reaction formation transference, counter-transference and sublimation
physical sensations, emotions and behaviours
147
Which of the following treatments is ECT licensed for? alcohol dependence borderline personality disorder life-threatening depression panic disorder social anxiety
life-threatening depression
148
What is the typical representation of deterioration of a patient with vascular dementia?
stepwise deterioration
149
A 78 y.o. man presents with symptoms of hypomania and wight loss. He has no previous psychiatric history of note. He has smoked 20 cigarettes per day since leaving school. On cognitive testing he takes over 5 mins attempting to complete the visuospatial part. Where is the most likely site of any lesion causing this performance? anterior temporal lobe frontal lobe medial temporal lobe occipital lobe parietal lobe
frontal lobe
150
A 23 y.o. man with schizophrenia is admitted after a relapse. A formulation box plot is constructed for him which is the bio-psycho-social model. According to the table, what type of aetiological factor is his job loss? biological precipitating biological predisposing psychological perpetuating social perpetuating social precipitating
social precipitating
151
A 42 y.o. man with bipolar affective disorder has a relapse after stopping his prescribed medication. He is depressed and has a plan to end his life by suicide. The team want to admit him to hospital in order to maintain his safety and start treatment with Lithium. The gentleman as he sees no point in living as a result of his severe depression. Section 1 of MHA Section 12 of MHA Section 17A supervised community treatment order (CTO) Section 2 of MHA Section 3 of MHA Section 4 of MHS Section 5(2) of MHA Section 5(4) of MHA Section 136 of MHA
Section 3
152
A 23 y.o. woman is brought to ED by her parents. they are worries as she has come home from university and told them she is hearing a voice telling her to hurt her 12 y.o. brother. She is struggling to ignore the voice and the family are worries she might act on the instructions. She has never been unwell in the past and there is no family history of any physical or mental illness. This lady refuses further support from community services and refuses to be admitted to hospital. Section 1 of MHA Section 12 of MHA Section 17A supervised community treatment order (CTO) Section 2 of MHA Section 3 of MHA Section 4 of MHS Section 5(2) of MHA Section 5(4) of MHA Section 136 of MHA
Section 2
153
A 20 y.o. man is found by the police standing on a bridge. When the police approach he says he is going to jump off as he wants to die. He tells the police his life is not worth living and he can see no future for himself. The police ring the local crisis team for advice and are told to bring him to a safe place for an assessment. Section 1 of MHA Section 12 of MHA Section 17A supervised community treatment order (CTO) Section 2 of MHA Section 3 of MHA Section 4 of MHS Section 5(2) of MHA Section 5(4) of MHA Section 136 of MHA
Section 136 of MHA
154
A 79 y.o. man presents to the ED because he cannot live in his house anymore. He says it has been bugged by the neighbours and they are piping music into his front room to annoy him. He can hear them laughing when he gets upset by this. He says the police have not helped and if you don't help he will go round to the neighbours with a kitchen knife. On examination there is no evidence of any physical disorder, and he has no previous mental health problems. Section 1 of MHA Section 12 of MHA Section 17A supervised community treatment order (CTO) Section 2 of MHA Section 3 of MHA Section 4 of MHS Section 5(2) of MHA Section 5(4) of MHA Section 136 of MHA
Section 2 of MHA
155
A 35 y.o. woman who took a deliberate overdose of paracetamol 3 days ago is on MAU. She requires further treatment as her liver has been damaged. She tells you she wants to leave the hospital as she need to buy more tablets to end her life. You feel she needs further assessment by a psychiatrist but they cannot attend immediately. Section 1 of MHA Section 12 of MHA Section 17A supervised community treatment order (CTO) Section 2 of MHA Section 3 of MHA Section 4 of MHS Section 5(2) of MHA Section 5(4) of MHA Section 136 of MHA
Section 5(2)
156
A 33 y.o. electrician is brought to his GP by his wife. He has a four week history of sleep disturbance with initial insomnia and early waking, irritability and racing thoughts. He talks rapidly and says he has remortgaged his house as he is planning to buy a private passenger jet. He has spent £12,000 in organising this. He has no previous psychiatric history. alcohol dependence syndrome anorexia nervosa generalised anxiety disorder bipolar affective disorder borderline personality disorder bulimia nervosa dementia depressive episode manic episode paranoid schizophrenia post traumatic stress disorder
manic episode
157
A 59 y.o. woman complains of poor concentration over the last few months. She says she feels tired all the time. She feels low and hopeless. She has made a will recently as she is convinced she will die in the next few weeks. alcohol dependence syndrome anorexia nervosa generalised anxiety disorder bipolar affective disorder borderline personality disorder bulimia nervosa dementia depressive episode manic episode paranoid schizophrenia post traumatic stress disorder
depressive episode
158
A 21 y.o. physiotherapy student sees her GP as she is worried about her weight. She enjoys running and has completed 4 marathons this year. She is concerned that she has been gaining weight despite limiting her calorie intake to under 1200 calories a day. Her height is 158cm and her weight is 43kg. alcohol dependence syndrome anorexia nervosa generalised anxiety disorder bipolar affective disorder borderline personality disorder bulimia nervosa dementia depressive episode manic episode paranoid schizophrenia post traumatic stress disorder
anorexia nervosa
159
a 45 y.o. man is under the care of the assertive outreach team. He has been treated for 20 years for an illness which has caused him to lose contact with all friends from his childhood. He is able to live independently but cannot work due to his mental disorder. he takes an injection medication once a month to manage his symptoms of thought disorder and auditory hallucinations. alcohol dependence syndrome anorexia nervosa generalised anxiety disorder bipolar affective disorder borderline personality disorder bulimia nervosa dementia depressive episode manic episode paranoid schizophrenia post traumatic stress disorder
paranoid schizophrenia
160
A 28 y.o. man is seen in outpatients. He was a passenger in a car crash 3 months ago. He feels 'cut off' from his family and has lost pleasure in spending time with them. He has vivd dreams of the car crash and gets flashbacks of the experience if he sits in a passenger seat on any car journey. alcohol dependence syndrome anorexia nervosa generalised anxiety disorder bipolar affective disorder borderline personality disorder bulimia nervosa dementia depressive episode manic episode paranoid schizophrenia post traumatic stress disorder
post traumatic stress disorder
161
A 25 y.o. woman is detained by the police. In custody she appears euphoric but later becomes quiet and difficult to rouse. On examination, the custody suite nurse finds she has a heart rate of 50 beats per minute, a respiratory rate of 4 breaths per minute and blue lips. Alcohol Amphetamine Barbiturates Cannabis Cocaine Ecstasy Ketamine Mephedrone Methadone Solvents
Methadone
162
A 23 y.o. man tells his friends that he thinks that everyone can tell which drug he has been taking. He says he is feeling really nervous and anxious about this but his friends note that he has been ravenously eating several bags of crisps and a pizza whilst discussing these fears. Alcohol Amphetamine Barbiturates Cannabis Cocaine Ecstasy Ketamine Mephedrone Methadone Solvents
cannabis
163
A 25 y.o. man is arrested after running down a dual carriageway. He resists arrest as he reports that he is being chased by large dark aliens which he can see. They hiss at him and tell him they are going to kill him. He believes the aliens are in league with the army who are hunting him and want to kill him. He tells his story clearly and rationally but is extremely agitated and restless. Alcohol Amphetamine Barbiturates Cannabis Cocaine Ecstasy Ketamine Mephedrone Methadone Solvents
amphetamine
164
A 24 y.o. man is arrested for driving under the influence of drugs. He says that he can see sounds, taste colours and hear the smells. He can see flocks of coloured butterflies in his cell. He has slurred speech and tells the custody officer that he looks all wavy and weird. After a few hours his symptoms dissipate but he starts to complain of lower abdominal pains. Alcohol Amphetamine Barbiturates Cannabis Cocaine Ecstasy Ketamine Mephedrone Methadone Solvents
Ketamine
165
A 17 y.o. is arrested at a festival after she threw her arms round a policeman and knocked him over. In custody she remains bright and energetic, and tells the custody officer he is beautiful and has lovely eyes. Alcohol Amphetamine Barbiturates Cannabis Cocaine Ecstasy Ketamine Mephedrone Methadone Solvents
ecstasy
166
A 25 y.o. woman who is moderately depressed without suicidal ideation. She wants help to improve her mood but does not want to take antidepressant medication. Benzodiazepine meds Clozapine treatment Cognitive behavioural therapy Depot anti-psychotic Electroconvulsive therapy In-patient admission Psychoanalytical psychotherapy Referral to occupational therapist Visits from a community psychiatric nurse
Cognitive behavioural therapy
167
A 32 y.o. man with hallucinations and delusions is unable to work because of his symptoms. He struggles to take tablets on a regular basis but has responded well to treatment with haloperidol in the past. He would like to try a treatment that could reduce his symptoms and enable him to work. Benzodiazepine meds Clozapine treatment Cognitive behavioural therapy Depot anti-psychotic Electroconvulsive therapy In-patient admission Psychoanalytical psychotherapy Referral to occupational therapist Visits from a community psychiatric nurse
Depot anti-psychotic
168
A 45 y.o. woman has become increasingly low and withdrawn over the past two months. She has suffered with depression in the past and attempted to end her life by suicide three years ago. She feels hopeless and has told her friends that she has bought several packets of ibuprofen which she wants to take to end her life. Benzodiazepine meds Clozapine treatment Cognitive behavioural therapy Depot anti-psychotic Electroconvulsive therapy In-patient admission Psychoanalytical psychotherapy Referral to occupational therapist Visits from a community psychiatric nurse
In-patient admission
169
A 75 y.o. man with recurrent depressive disorder is admitted to hospital under section 3 of the Mental Health Act. He believes that his insides have 'died' and so has stopped eating and drinking. He is refusing all tablet medication. his kidney function is so poor he needs IV fluids. His life is at risk without urgent treatment. Benzodiazepine meds Clozapine treatment Cognitive behavioural therapy Depot anti-psychotic Electroconvulsive therapy In-patient admission Psychoanalytical psychotherapy Referral to occupational therapist Visits from a community psychiatric nurse
Electroconvulsive therapy - he is catatonic depressive
170
While planning the discharge from hospital of a 41 y.o. man with chronic schizophrenia, the hostel where he normally lives is concerned about possible risks when he is preparing meals when he is on his own, especially around fire safety. Benzodiazepine meds Clozapine treatment Cognitive behavioural therapy Depot anti-psychotic Electroconvulsive therapy In-patient admission Psychoanalytical psychotherapy Referral to occupational therapist Visits from a community psychiatric nurse
Referral to occupational therapist