Pathogen Virulence - Virulence Factors

Question 1

Define Virulence

Answer 1

The ability of a pathogen to cause disease

Question 2

Define Pathogenesis:

Answer 2

How a disease/ pathogen infects and spreads

Question 3

Adherence Factors:

Answer 3

Bacteria that colonize mucosal sites by using pili / fimbriae to adhere/ stick to cells

Question 4

Endotoxins

Answer 4

A pathogenic toxic that is bound to its outer membrane and cannot spread further into the body

Question 5

Exotoxins

Answer 5

A protein that is produced and released by a pathogen

Question 6

Impacts caused by Endotoxins

Answer 6

Fever, changes in blood temperature, inflammation, lethal shock/ other lethal events

Question 7

Major Exotoxin Categories

Answer 7

Cytotoxins, neurotoxins, enterotoxins

Question 8

Purpose of Flagella

Answer 8

Allows for the bacteria to move around - (corkscrew movement)
Propels the cell forward and burrow into the flesh

Question 9

Colonisation Factor

Answer 9

Protein that allows for a pathogen to colonise the host’s body

Question 10

Invasion Factor

Answer 10

Protein that allows pathogens to colonise the host’s body

Question 11

Toxin

Answer 11

Protein produced and released by a pathogen