Pathological Anatomy MCQ's

Question 1

1. The typical clinical manifestation of renal amyloidation is following:

a) acute renal failure
b) nephrotic syndrome
c) nephritic syndrome

Answer 1

Nephrotic syndrome

Question 2

2. Injury of glomeruli of different aetiology with the thickening of basal membrane, but without inflammatory reaction and proliferation of mesangial cells, is called:

a) membranoproliferative glomerulonephritis
b) membranous glomerulonephritis
c) mesangial glomerulonephritis

Answer 2

Membranous glomerulonephritis

Question 3

3. Acute renal failure develops in patients with:
   a) kidney amyloidosis
   b) rapidly progressive glomerulonephritis
   c) acute tubular necrosis
   d) b+c

Answer 3

b+c

Question 4

4. Nephrotic syndrome is caused by such renal glomerular diseases as:
   a) minimal change glomerulopathy
   b) membranous glomerulonephritis
   c) tubulointerstitial nephritis
   d) a+b
   e) b+c

Answer 4

Membranous glomerulonephritis

Question 5

5. Pyelonephritis is the inflammation of:
   a) urinary bladder
   b) renal pelvis
   c) renal pelvis and interstitial space of kidney

Answer 5

Renal pelvis

Question 6

6. The prognosis of minimal change glomerulopathy is:
   a) frequently beneficial, with preserved renal function
   b) rapid loss of kidney function is observed

Answer 6

Frequently beneficial with preserved renal function

Question 7

7. Endocapillary glomerulonephritis can be proceeded by:
   a) Circulation disturbances
   b) Infection
   c) Amyloidosis

Answer 7

Infection

Question 8

8. Membranous glomerulonephritis:
   a) is always isolated (primary) disease
   b) can be sequel of other diseases (secondary aetiology)

Answer 8

Can be a sequel of other diseases (secondary aetiology)

Question 9

9. Nephritic syndrome may be caused by following glomerular diseases:
   a) Endocapillary proliferative glomerulonephritis
   b) Tubulointerstitial nephritis
   c) Diabetic glomerulopathy

Answer 9

Endocapillary proliferative glomerulonephritis

Question 10

10. Rapidly progressing glomerulonephritis is clinically characterized by:
    a) acute renal failure
    b) nephrotic syndrome
    c) nephritic syndrome

Answer 10

Acute renal failure

Question 11

11) If amyloid is found in liver, it is:
a) local amyloidosis
b) systemic amyloidosis

Answer 11

Systemic amyloidosis

Question 12

12) The cause of AA amyloidosis is:
a) Long term chronic inflammation
b) Dysfunction of plasma cells
c) congenital mutations

Answer 12

Long term chronic inflammation

Question 13

13) Amyloid is characterised by:
a) structure of α-spiral
b) structure of β-plate
c) Presence of collagen

Answer 13

Structure of β-plate

Question 14

14) The most common variation of nephrolithiasis is:
a) Calcium oxalate and phosphate stones
b) urate stones
c) cystine stones

Answer 14

Calcium oxalate and phosphate stones

Question 15

15) Which is/are most common renal tumors in adults:
a) clear cell carcinoma
b) oncocystoma
c) mesoblastic nephroma
d) breast carcinoma

Answer 15

Clear cell carcinoma

Question 16

16) The most common renal tumor in children is:
a) clear cell renal carcinoma
b) nephroblastoma
c) Abscess of kidney

Answer 16

Nephroblastoma

Question 17

17) Most common type of renal carcinoma is:
a) Angiomyolipoma
b) clear cell carcinoma
c) Papillary carcinoma
d) squamous cell carcinoma

Answer 17

Clear cell carcinoma

Question 18

18) To detect characteristics of „N“ of clear cell carcinoma, following data must be taken into consideration:
a) The largest diameter of tumour
b) Metastasis in the regional lymph nodes
c) invasion into large veins

Answer 18

Metastasis in the regional lymph nodes

Question 19

19) Which of the listed renal tumours are benign: (?)
a) clear cell carcinoma
b) Angiomyolipoma
c)
d) oncocytoma
e) A+B
f) B + D

Answer 19

Angiomyolipoma and oncocytoma

Question 20

20) Which of the processes starts in the subcapsular part of prostate?
a) prostatic carcinoma (?)
b) benign hyperplasia of prostate
c) prostatitis

Answer 20

Prostatic carcinoma

Question 21

21. Benign hyperplasia of prostate is characterized by:
    A) Hormonal disorders
    b) activation of mesenchymal cells
    c) hyperplasia of epithelial and stromal cells
    d) A+B+C

Answer 21

A+B+C

Question 22

22. Prostatic carcinoma is characterized by:
    a) Expansive type of growth
    b) Invasive type of growth
    c) Perineural invasion
    d) A+b
    e) B+c

Answer 22

Invasive type of growth

Question 23

23. If patient at the moment of diagnosis of prostatic carcinoma has metastasis in vertebra, it is classified as:
    a) T4
    b) N2
    c) M1

Answer 23

M1

Question 24

24. Seminoma is tumor of:
    a) prostate
    b) kidney
    c) testis
    d) uterus

Answer 24

Testis

Question 25

25. Embryonic carcinoma is characterized by: A) expansive type of growth b) invasive type of growth c) development of lymphogenous metastases d) development of haematogenous metastases e) a+b f) b+c g) b+c+d

Answer 25

Development of haematogenous metastases

Question 26

26. What is the typical age of patients with testicular tumors: a) newborns and kids b) young males c) old males

Answer 26

Young males

Question 27

27. Which tumor has tendency to invade veins and to reach v. cava inferior? A) prostatic carcinoma b) renal carcinoma c)lipocarcinoma

Answer 27

Renal carcinoma

Question 28

28. Risk factors of carcinoma of urinary bladder include the following: a) developmental defects b) work in dye factory c) smoking d) a+b e) b+c

Answer 28

Work in dye factory and smoking

Question 29

29. Letter “N” or urinary bladder carcinoma (TNM classification) means: a) metastases in the regional lymph nodes b) diameter of lymph nodes with metastases c) diameter of secondary tumors in liver

Answer 29

Metastases in the regional lymph nodes

Question 30

30. Clinical significance of benign hyperplasia of prostate is high due to: a) high risk of malignisation b) disturbances of urination c) risk of infection of urinary system d) a+b e) b+c

Answer 30

Disturbances of urination

Question 31

``` 31. chronic renal disease( chronic renal insufficiency can be caused by: A glomerular disease B Tubularinterstitial disease C renal vascular pathology D all of the above listed ```

Answer 31

All of the above listed

Question 32

32. Autosomal dominant polycystic kidney disease usually results in chronic renal disease V necessitating transplantation A in the newborn B in adults C only in women

Answer 32

In the newborn

Question 33

33. the necrosis of myocardial fibers in the case of myocardial infarction is followed by A infiltration of neutrophilic leukocytes B granulomatous inflammation C proliferation of the dead cardiomyocytes

Answer 33

Infiltration of neutrophilic leukocytes

Question 34

34. Acute mastits typical develops: A during lactation B in patients suffering from severe atherosclerosis C in newborn

Answer 34

During lactation

Question 35

35. Which epidemiological estimate characterizes fibrocystic breast disease most correctly A fibrocystic breast disease is frequent B fibrocystic breast disease is very rare

Answer 35

Fibrocystic breast disease is frequent

Question 36

36. Sclerosing adenosis is characterized A by widespread metastases B by invasive growth C by hyperplastic process resulting in increased number of acini

Answer 36

By hyperplastic process resulting in increased number of acini

Question 37

``` 37.breast papilloma is A benign epithelial tumor B benign mesenchymal tmor C malignant epithelial tumor D malignant mesenchymal tumor ```

Answer 37

Benign epithelial tumor

Question 38

38. most common benign tumor in female breast is A tubular adenoma B fibroadenoma C lobular cancer

Answer 38

Fibroadenoma

Question 39

39. which of the following pathologic processes has significant risk of invasive breast cancer A sclerosing adenosis B fibrocystic breast disease C carcinoma in situ

Answer 39

Carcinoma in situ

Question 40

``` 40. the risk factor of breast cancer include: A early menarche B late menopause C inherited BRCA 1 gene mutation D all of these factors ```

Answer 40

All of these factors

Question 41

41. The risk of breast cancer in BRCA 1 mutation carrying females is A 5-10% B 60-850% C 100%

Answer 41

60-85%

Question 42

42. The most frequent histological type of breast cancer is A squamous cell cancer B papilloma C ductal cancer

Answer 42

Ductal cancer

Question 43

``` 43. If the patient has breast cancer and metastasis of breast cancer in her lungs, this is classified as A T3 B T4 C N2 D M1 ```

Answer 43

M1

Question 44

``` 44. the location of primary melanoma can be A skin B anorectal mucosa C ovarium D A+B E A+C F B+C ```

Answer 44

A+B

Question 45

45. Which types of growth of melanoma is evaluated by Clark classification A radial growth B vertical growth C both

Answer 45

Vertical growth

Question 46

``` 46. Lipoma is A benign tumor of myocytes B malignant tumor of myocytes C benign tumor of adipocytes D malignant tumor of adipocytes ```

Answer 46

Benign tumor of adipocytes

Question 47

47. Typical sited of leiomyloma … A deep soft tissue of limbs B uterus C retroperitoneum D A+B E B+C WIR KONNTEN NICHT ERKENNEN, IN WELCHER FRAGE F A+C LEIOMYOMA ODER LEIOMYSARCOMA STEHT, DESWEGEN

Answer 47

Uterus

Question 48

``` 48. typical sites of leiomyosarcoma … A skin B Uterus C retroperitoneum D A+B E B+C F A+C ```

Answer 48

A+C

Question 49

``` 49. tumor in which atypical cells produce bone Matrix A Osteoma B Osteosarcoma C Chondroma D Chondrosarcoma ```

Answer 49

Osteosarcoma

Question 50

50. gastrointestinal stromal tumor expresses the following A S. 100 B CD 117 C desmin

Answer 50

CD 117