Pathology Flashcards

(39 cards)

1
Q

Most common benign chest wall tumour

A

Lipoma

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2
Q

Most common pleural neoplasm

A

Mets

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3
Q

Metastasis of pleura most commonly which subtype

A

Adenocarcinoma

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4
Q

Most common cause of pleural effusion over 50

A

1- cardiac

2- mets

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5
Q

Most common primary adult tumour of anterior mediastinum

A

Thymoma

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6
Q

Most common extragonadal site for GCT

A

Anterior mediastinum

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7
Q

Most common cause of intrathoracic lymphadenopathy

A

Sarcoidosis

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8
Q

Most common posterior mediastinal mass in adults

A

Peripheral nerve sheath tumour

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9
Q

Neuroblastoma most common extraabdominal location

A

Posterior mediastinum

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10
Q

Most common primary pericardial malignancy

A

Mesothelioma

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11
Q

Tracheobronchomalacia associations

A

Tracheobronchomegaly, COPD, relapsing polychondirtitis

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12
Q

Most common cause of emphysema

A

Smoking

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13
Q

Centrilobular emphysema cause

A

Smoking

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14
Q

Panlobular emphysema cause

A

A antitripsin definciency

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15
Q

Whole lung collapse appearance on lateral X-ray

A

Accentuation of retrosternal space

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16
Q

Benign lesion timeline

A

Less than 1 month more than 18 months

17
Q

Benign lesion HU

A

Less than 15 post IV

18
Q

Optimal modality for superior sulcus tumour

19
Q

Major factors for malignancy

A

Attenuation above 15 HU post IV and interval growth

20
Q

Criteria for respectability of tumour

A

< 3 cm of contact with the mediastinum
<90 degree contact with the aorta
Visible fat between mass and any vital structure

21
Q

Commonest tumour to cavitate

22
Q

Military Mets

A

Thyroid and Renal

23
Q

LIP associations

A

Sjogrens
Bone marrow transplant
HIV
Castlemans

24
Q

Causes of eggshell nodal calcification

A
Sarcoidosis 
Silicosis
Hisoptoplasmosis
Lymphoma
Blastomycosis
Amyloidosis
25
Sarcoidosis diagnosis
Transbronchial biopsy
26
Stages of sarcoidosis
``` 0 normal 1 lymphadenopathy 2 lymphadenopathy and parenchyma opacification 3 only opacification of parenchyma 4 fibrosis ```
27
Sjogren most common lung entity
Nsip
28
Polymo/dermatomyositis most common presentation
Aspiration pneumonia
29
Causes of bilateral upper lobe fibrosis
``` Sarcoidosis Ankylosing spondylitis Tb ABPA Histoplasmosis ```
30
ARDS early manifestations
Dense Consolidation GG consolidation Bronchial dilatation Cysts
31
Most common cancer type in pancoast
Adenocarcinoma
32
Endobronchial Metastasis
Breast, rcc | ,thyroid, rectal
33
Signs of active tb
``` Consolidation Thick wall cavity Pleural effusion Rim enhancing lymph node Centrilobular nodules Clustred nodules Miliary nodules ```
34
Bilateral upper lobe fibrosis
``` A TEA SHOP A: allergic bronchopulmonary aspergillosis T: tuberculosis E: extrinsic allergic alveolitis A: ankylosing spondylitis S: sarcoidosis H: histiocytosis O: occupational (silicosis, berylliosis) P: pneumoconiosis (coal workers ```
35
Cavitary lesions causes
Mnemonic C: cancer lung cancer: most frequently squamous cell carcinoma (SCC) cavitary pulmonary metastasis(es): most frequently SCC A: autoimmune; granulomas from granulomatosis with polyangiitis rheumatoid arthritis (rheumatoid nodules) V: vascular (both bland and septic pulmonary emboli) I: infection (bacterial/fungal) pulmonary abscess pulmonary tuberculosis T: trauma - pneumatoceles Y: youth CPAM (congenital pulmonary airway malformation) pulmonary sequestration bronchogenic cyst
36
Most common cause of SVC obstruction
Small cell lung cancer
37
Pulmonary avm associations
hereditary hemorrhagic telangiectasia (HHT) frequently have PAVMs 1; hepatic cirrhosis (as part of the hepatopulmonary syndrome) schistosomiasis mitral stenosis trauma previous cardiac surgery (e.g. Glenn and Fontan procedures for cyanotic congenital heart disease) 7 actinomycosis: thoracic actinomycosis infection Fanconi syndrome metastatic thyroid carcinoma tuberculosis 13,14 (Rasmussen aneurysm)
38
Causes of pulmonary eosinophelia
Drugs antibiotics nitrofurantoin (which may progress to pulmonary fibrosis) penicillin tetracycline toxins eosinophilia-myalgia syndrome from contaminated L-tryptophan toxic oil syndrome See also: drug rash with eosinophilia and systemic symptoms (DRESS). Infection fungal Aspergillus fumigatus (asthmatic pulmonary eosinophilia) parasitic schistosomiasis (50% have pulmonary involvement) ascaris Toxocara canis microfilariasis (tropical eosinophilia) strongyloidiasis - pulmonary strongyloidiasis
39
Rib notching causes
Superior rib notching ``` abnormal osteoblastic activity osteogenesis imperfecta connective tissue diseases rheumatoid arthritis systemic lupus erythematosus (SLE) Marfan syndrome Sjogren syndrome scleroderma 3 local pressure abnormal osteoclastic activity hyperparathyroidism miscellaneous neurofibromatosis type 1 restrictive lung disease poliomyelitis progeria abnormal muscle pull ``` Inferior rib notching enlarged collateral vessels coarctation of the aorta (Roesler sign) interrupted aortic arch subclavian artery obstruction Takayasu disease Blalock-Taussig shunt: involves only upper two rib spaces arteriovenous malformation (AVM) of the chest wall superior vena cava obstruction with enlarged venous collaterals pulmonary AVM tetralogy of Fallot 4 neurogenic tumors schwannoma (usually single) neurofibromatosis type 1 (rarely can be superior if neurofibroma is very large) Superior and inferior rib notching hyperparathyroidism neurofibromatosis type 1