PATHOLOGY Flashcards Preview

Question 1

1

Most common form of testicular neoplasm in men > 60 years of age

Answer

Testicular lymphoma

Question 2

2

Sex cord-stromal tumor with Crystalloids of Reinke (25%)

Answer

Leydig Cell Tumor

Question 3

3

Embryonal Carcinoma with Schiller-Duval Bodies/glomeruloid (50%)

Answer

Yolk Sac Tumor

Question 4

4

Tumor marker for prostatic adenocarcinoma when PSA is elevated but with normal biopsy

Answer

PCA 3 (Prostate Cancer Gene 3)

Question 5

5

Most common site of prostate adenocarcinoma metastasis

Answer

Lumbar spine 》 proximal femur 》 pelvis 》 thoracic spine 》 ribs

Question 6

6

Tennis racket cytoplasmic organelles

Answer

Birbeck granules/bodies in Langerhans cell histiocytosis

Question 7

7

HPV type in condyloma acuminata

HPV 6, 11

Answer

Gonococcus and Chlamydia

Answer

Schiller Test. (+) Pale staining areas

Answer

Start at 21 or within 3 years after first coitus, every 3 years until 30

Answer

Dysgerminoma

Answer

Yolk sac tumor

Answer

Meig Syndrome

Answer

Granulosa cell tumor

Answer

Krukenberg tumor

Answer

Invasive lobular carcinoma

Answer

Fibroadenoma (stromal tumor)

Answer

Gains in Ch1q

Answer

De Quervain thyroiditis

Answer

Struma ovarii

Answer

Congenital iodine deficiency

Answer

Hashimoto (Autoimmune)

Answer

Hurthle cell

Answer

Medullary thyroid carcinoma

Answer

Von Recklinghausen disease of the bone

Answer

Kimmelsteil-Wilson Disease

Answer

Waterhouse-Friedrichsen Syndrome (Primary Acute Adrenocortical Insufficiency)

Answer

N. meningitidis

Answer

Chromaffin cells

Answer

10% extra-adrenal, 10% bilateral, 10% malignant, 10% NOT associated with hypertension

Answer

MEN 1 (Wermer Syndrome)

Answer

MEN 2A (Sipple Syndrome)

Answer

Leser-Trelat sign

Answer

Koebner Phenomenon

Answer

Auspitz Sign (Psoriasis)

Answer

Spongiform pustules of Kogoj and Munro microabscess

Answer

Osteopetrosis (Marble Bone Disease) aka Albers-Schonberg Disease

Answer

Osteopetrosis

Answer

Osteogenesis Imperfecta (Brittle Bone Disease)

Answer

Hemangioma

Answer

Wilson disease (hepatolenticular degeneration)

Answer

KRAS oncogene

Answer

p16 mutation

Answer

p53, BRCA2, DPC4/SMAD4

Answer

Trousseau sign

Answer

Cholesterolosis

Answer

Cholesterolosis

Answer

Councilman bodies

Answer

Mallory bodies

Answer

Mallory bodies

Answer

Mallory bodies

Answer

Mallory bodies

Answer

Mallory bodies

Answer

Mallory bodies

Answer

Mallory bodies

Question 8

8

Most common etiologic agents for pelvic inflammatory disease

Question 9

9

Visual inspection of cervix with Lugol's solution? High risk for cervical cancer if?

Question 10

10

Schedule of Papanicolaou Smear

Question 11

11

Most common malignant germ cell tumor in females

Question 12

12

Second most common malignant germ cell tumor in females

Question 13

13

Tumor marker for dygerminoma

KIT

Question 14

14

Tumor marker for yolk sac tumor

AFP

Question 15

15

Tumor marker for ovarian choriocarcinoma

HCG

Question 16

16

Hydrothorax, ascites, ovarian tumor

Question 17

17

Sex-chord stromal tumors with Call-Exner bodies

Question 18

18

Signet ring GI carcinoma metastatic to the ovaries

Question 19

19

Discohesive infiltrating tumor cells in single file (Indian file)

Question 20

20

Most common benign tumor of female breast

Question 21

21

Most common genetic abnormality in phyllodes tumor (stromal tumor)

Question 22

22

Granulomatous thyroiditis causing thyrotoxicosis

Question 23

23

Ovarian teratoma with ectopic thyroid causing thyrotoxicosis

Question 24

24

MCC of congenital hypothyroidism worldwide

Question 25

25

MCC of hypothyroidism in iodine-sufficient areas

Question 26

26

Metaplastic response characterized by abundant, eosinophilic, granular cytoplasm in Hashimoto

Question 27

27

Thyroid carcinoma with high levels of calcitonin but usually without hypocalcemia

Question 28

28

Increase osteoclastic activity, peritrabecular fibrosis, cystic brown tumors

Question 29

29

Nodular glomerulosclerosis of diabetes mellitus

Question 30

30

Massive bilateral adrenal hemorrhage as a complication of disseminated bacterial infection

Question 31

31

Bacteria associated with Waterhouse-Friedrichsen Syndrome

Question 32

32

Cytogenetic origin of pheochromocytoma

Question 33

33

Rule of 10s in pheochromocytoma

Question 34

34

Prolactinoma (pituitary), Primary Hyperparathyroidism (parathyroid), Insulinoma or Gastrinoma (pancreas)

Question 35

35

Mutation in Wermer Syndrome

MEN 1

Question 36

36

MEN associated with parathyroid hyperplasia

Question 37

37

MEN associated with neuromas, gangliomas, and Marfanoid habitus

MEN 2B

Question 38

38

MEN 2 mutations

RET

Question 39

39

Rapid increase in seborrheic keratosis as paraneoplastic syndrome of GI malignancies

Question 40

40

Lesions appear on sites of trauma in psoriasis

Question 41

41

Pinpoint bleeding on lifting of scales due to dilated tortuous vessels in dermal papillae

Question 42

42

Inflammatory infiltrates in psoriasis

Question 43

43

Impaired osteoclast function leads to excessive bone formation

Question 44

44

First disorder to be treated with hematopoeitic stem cell transplantation

Question 45

45

Most common inherited disorder of connective tissue

Question 46

46

Most common benign tumor of the liver

Question 47

47

Autosomal recessive disorder of copper metabolism

Question 48

48

Oncogene activated in Pancreatic intraductal neoplasia 1A and 1B

Question 49

49

Gene mutation in PanIN2

Question 50

50

Gene mutation in PanIN3

Question 51

51

Migratory thrombophlebitis in adenocarcinoma of the pancreas (sign)

Question 52

52

Also known as strawberry gallbladder (yellow cholesterol-containing flecks in GB mucosal surface

Question 53

53

Also known as strawberry gallbladder (yellow cholesterol-containing flecks in GB mucosal surface)

Question 54

54

Apoptotic hepatocytes first identified in yellow fever

Question 55

55

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

Question 56

55

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

Question 57

55

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

Question 58

56

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

Question 59

56

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

Question 60

56

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

Question 61

56

PATHOLOGY Flashcards Preview

PHI REVIEW > PATHOLOGY > Flashcards

Most common form of testicular neoplasm in men > 60 years of age

Testicular lymphoma

Sex cord-stromal tumor with Crystalloids of Reinke (25%)

Leydig Cell Tumor

Embryonal Carcinoma with Schiller-Duval Bodies/glomeruloid (50%)

Yolk Sac Tumor

Tumor marker for prostatic adenocarcinoma when PSA is elevated but with normal biopsy

PCA 3 (Prostate Cancer Gene 3)

Most common site of prostate adenocarcinoma metastasis

Lumbar spine 》 proximal femur 》 pelvis 》 thoracic spine 》 ribs

Tennis racket cytoplasmic organelles

Birbeck granules/bodies in Langerhans cell histiocytosis

HPV type in condyloma acuminata

HPV 6, 11

Most common etiologic agents for pelvic inflammatory disease

Gonococcus and Chlamydia

Visual inspection of cervix with Lugol's solution? High risk for cervical cancer if?

Schiller Test. (+) Pale staining areas

Schedule of Papanicolaou Smear

Start at 21 or within 3 years after first coitus, every 3 years until 30

Most common malignant germ cell tumor in females

Dysgerminoma

Second most common malignant germ cell tumor in females

Yolk sac tumor

Tumor marker for dygerminoma

KIT

Tumor marker for yolk sac tumor

AFP

Tumor marker for ovarian choriocarcinoma

HCG

Hydrothorax, ascites, ovarian tumor

Meig Syndrome

Sex-chord stromal tumors with Call-Exner bodies

Granulosa cell tumor

Signet ring GI carcinoma metastatic to the ovaries

Krukenberg tumor

Discohesive infiltrating tumor cells in single file (Indian file)

Invasive lobular carcinoma

Most common benign tumor of female breast

Fibroadenoma (stromal tumor)

Most common genetic abnormality in phyllodes tumor (stromal tumor)

Gains in Ch1q

Granulomatous thyroiditis causing thyrotoxicosis

De Quervain thyroiditis

Ovarian teratoma with ectopic thyroid causing thyrotoxicosis

Struma ovarii

MCC of congenital hypothyroidism worldwide

Congenital iodine deficiency

MCC of hypothyroidism in iodine-sufficient areas

Hashimoto (Autoimmune)

Metaplastic response characterized by abundant, eosinophilic, granular cytoplasm in Hashimoto

Hurthle cell

Thyroid carcinoma with high levels of calcitonin but usually without hypocalcemia

Medullary thyroid carcinoma

Increase osteoclastic activity, peritrabecular fibrosis, cystic brown tumors

Von Recklinghausen disease of the bone

Nodular glomerulosclerosis of diabetes mellitus

Kimmelsteil-Wilson Disease

Massive bilateral adrenal hemorrhage as a complication of disseminated bacterial infection

Waterhouse-Friedrichsen Syndrome (Primary Acute Adrenocortical Insufficiency)

Bacteria associated with Waterhouse-Friedrichsen Syndrome

N. meningitidis

Cytogenetic origin of pheochromocytoma

Chromaffin cells

Rule of 10s in pheochromocytoma

10% extra-adrenal, 10% bilateral, 10% malignant, 10% NOT associated with hypertension

Prolactinoma (pituitary), Primary Hyperparathyroidism (parathyroid), Insulinoma or Gastrinoma (pancreas)

MEN 1 (Wermer Syndrome)

Mutation in Wermer Syndrome

MEN 1

MEN associated with parathyroid hyperplasia

MEN 2A (Sipple Syndrome)

MEN associated with neuromas, gangliomas, and Marfanoid habitus

MEN 2B

MEN 2 mutations

RET

Rapid increase in seborrheic keratosis as paraneoplastic syndrome of GI malignancies

Leser-Trelat sign