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Flashcards in Pathology Deck (19)
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1
Q
Desquamative gingivitis is frequently associated with:
(A) ulcerative squamous cell carcinoma.
(B) plaque induced acute gingivitis.
(C) lichen planus.
(D) herpetiform infections.
A

C

2
Q
Ehlers-Danlos syndrome is caused by a defect of which of the following?
(A) Keratin
(B) Collagen
(C) Elastin
(D) Laminin
A

B

3
Q

Erosive lichen planus is best diagnosed by:
(A) brush biopsy.
(B) immunofluorescence of biopsy specimen.
(C) biopsy of active ulcer.
(D) biopsy of non-ulcerated area.

A

D

4
Q
A 50 year-old patient presents with a one week onset of increasingly painful vesicles of the oral and nasal mucosa. The patient is febrile and cannot tolerate oral intake. Immunohistochemistry reveals autoantibodies against epithelial intercellular bridge substances. An appropriate initial treatment would be:
(A) intravenous prednisone.
(B) intravenous gamma globulin.
(C) rituximab (Rituxan).
(D) plasmapheresis.
A

A

5
Q

Which is true regarding the use of a buccal fat pad graft for the closure of an oral-antral fistula?
(A) Graft survival depends upon primary mucosal coverage.
(B) Success is predictable in the presence of chronic sinusitis.
(C) It is a pedicled graft with an axial vascular pattern.
(D) This technique results in loss of vestibular depth.

A

C

6
Q

A 40 year-old African American female presents for evaluation of mixed radiolucent/radiopaque, round, non-corticated lesions involving the apices of the anterior mandibular teeth. The patient is asymptomatic. All of the mandibular anterior teeth test vital. Which of the following would be the recommended management?
(A) Obtain a CT scan to further evaluate the extent of the lesion
(B) Obtain a tissue biopsy to confirm the diagnosis
(C) No treatment is necessary
(D) Perform curettage of the lesions and send tissue for pathologic diagnosis

A

C

7
Q

Which of the following represents the most appropriate surgical management of an adenomatoid odontogenic tumor?
(A) En-bloc resection with delayed reconstruction
(B) A two-stage surgery: decompression followed by enucleation
(C) Enucleation and curettage
(D) En-bloc resection and excision of surrounding involved soft tissue

A

C

8
Q

Information that may guide the decision for elective neck dissection in patients with T1 and T2 oral cavity squamous cell carcinoma includes which of the following?
(A) Degree of differentiation
(B) Margin status at the time of diagnostic biopsy
(C) Length of time that the cancer has been present
(D) Tumor depth of invasion

A

D

9
Q
A metastatic tumor of the mandible in a 70 year-old man is most likely to originate in which of the following anatomic sites?
(A) Colon
(B) Kidney
(C) Lung
(D) Breast
A

C

10
Q
A 32 year-old patient presents with the following radiographic findings on a panorex film. Aspirations yield a creamy thick fluid while the biopsy shows a thin walled cystic structure with corrugated lining. This is most consistent with:
(A) dentigerous cyst.
(B) odontogenic keratocyst.
(C) ameloblastoma.
(D) myxoma.
A

B

11
Q
The ameloblastoma most commonly occurs as a:
(A) malignancy in soft tissue.
(B) benign process in soft tissue.
(C) malignancy in bone.
(D) benign process in bone.
A

D

12
Q

Which of the following statements regarding surgery for the ameloblastoma is true?
(A) The solid/multicystic variant of the ameloblastoma requires enucleation and curettage for cure.
(B) The unicystic variant of the ameloblastoma requires resection of the maxilla or mandible for cure.
(C) The peripheral ameloblastoma requires a resection of the maxilla or mandible for cure.
(D) The solid/multicystic variant of the ameloblastoma requires resection of the maxilla or
mandible for cure.

A

D

13
Q
Which of the following margins of uninvolved bone should be minimally resected with the solid/multicystic ameloblastoma so as to completely remove this tumor in the mandible?
(A) 16-20 mm
(B) 10-15 mm
(C) 6-9 mm
(D) 2-5 mm
A

A

14
Q
What is the most common presenting sign or symptom in patients with osteosarcoma of the jaws?
(A) Paresthesia
(B) Pain
(C) Swelling
(D) Mobility of teeth
A

C

15
Q

Resolution of oral bisphosphonate induced osteonecrosis will typically resolve:
(A) following vigorous debridement of the necrotic bone.
(B) with medical treatment using clindamycin 600 mg every 6 hours for 14 days.
(C) with hyperbaric oxygen therapy.
(D) without surgery during a period of a drug holiday.

A

D

16
Q

A 40 year-old African American female presents for evaluation of mixed radiolucent/radiopaque, round, non-corticated lesions involving the apices of the anterior mandibular teeth. The patient is asymptomatic. All of the mandibular anterior teeth test vital. Which of the following would be the recommended management?
(A) Obtain a CT scan to further evaluate the extent of the lesion
(B) Obtain a tissue biopsy to confirm the diagnosis
(C) No treatment is necessary
(D) Perform curettage of the lesions and send tissue for pathologic diagnosis

A

C

17
Q

Which of the following represents the most appropriate surgical management of an adenomatoid odontogenic tumor?
(A) En-bloc resection with delayed reconstruction
(B) A two-stage surgery: decompression followed by enucleation
(C) Enucleation and curettage
(D) En-bloc resection and excision of surrounding involved soft tissue

A

C

18
Q

Information that may guide the decision for elective neck dissection in patients with T1 and T2 oral cavity squamous cell carcinoma includes which of the following?
(A) Degree of differentiation
(B) Margin status at the time of diagnostic biopsy
(C) Length of time that the cancer has been present
(D) Tumor depth of invasion

A

D

19
Q
A metastatic tumor of the mandible in a 70 year-old man is most likely to originate in which of the following anatomic sites?
(A) Colon
(B) Kidney
(C) Lung
(D) Breast
A

C