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Flashcards in Pathology Findings Deck (28)
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0
Q

Findings in Coeliac disease?

A

Crypt hyperplasia with inflammatory cells in the mucosa

Total or subtotal villous atrophy

1
Q

Findings in Barrett’s oesophagus?

A

Metaplasia of lower oesophageal epithelium to gastric- or intestinal-type epithelium

2
Q

Findings in Crohn’s disease?

A

Macroscopic: skip lesions, cobblestone appearance, fissured ulcers
Microscopic: thickened wall, transmural inflammation, granulomas

3
Q

Findings in Ulcerative Colitis?

A

Mucosal/submucosal inflammation only, crypt abscesses, superficial ulceration

4
Q

Findings in Chronic Cholecystitis?

A

Chronic inflammatory changes

Rokitansky-Aschoff sinuses

5
Q

Findings in acute viral hepatitis?

A

Swelling of hepatocytes with spotty necrosis

Councilman bodies

6
Q

Findings in alcoholic hepatitis?

A

Fatty accumulation in cytoplasmic vacuoles, necrosis, Mallory hyaline material

7
Q

Findings in chronic active hepatitis?

A

Piecemeal necrosis

8
Q

Findings in autoimmune hepatitis?

A

Interface hepatitis, portal plasma cell infiltration

9
Q

Findings in haemochromatosis?

A

Excessive hepatic iron visible as Blue on Perl’s stain

10
Q

Findings in primary biliary cirrhosis?

A

Portal hepatitis, granulomatous destruction of bile ducts.

Later: periportal hepatitis and bile duct proliferation.

11
Q

Findings in liver cirrhosis?

A

Macroscopic: macro-/micronodular
Microscopic: fibrous tissue visible as red on von Gieson stain

12
Q

Findings in diffuse alveolar damage?

A

Alveolar hyaline membranes, thickened alveolar walls

13
Q

Findings in previous asbestos exposure?

A

Asbestos bodies

14
Q

Findings in pulmonary fibrosis?

A

Proliferation of Type II pneumocytes, thickening of alveolar walls

15
Q

Finding on renal biopsy in malignant hypertension?

A

Renal arteriolar fibrinoid necrosis

16
Q

Findings on renal biopsy in diabetic glomerulosclerosis?

A

Kimmelstein-Wilson nodules, thickened capillary basement membranes, hyalinisation of arterioles

17
Q

Findings in Hosgkin’s Disease?

A

Reed-Sternberg cells, abnormal lymph node architecture

Nodular sclerosing type has fibrous tissue

18
Q

Findings in myelofibrosis?

A

Bone marrow fibrosis 2ry to fibroblast proliferation

19
Q

Findings in Multiple Myeloma?

A

Plasma cell proliferation in bone marrow

20
Q

Findings on temporal artery biopsy in temporal arteritis?

A

May be normal

May have plasma cells, lymphocytes and multinucleate giant cells

21
Q

Findings in Polymyositis?

A

Muscle fibre necrosis

Lymphocyte infiltration

22
Q

Findings in acromegaly?

A

Pituitary acidophil macroadenomas (somatotroph adenomas)

23
Q

Findings in hyperprolactinaemia?

A

Pituitary chromophobe adenomas

24
Q

Findings in raised ACTH?

A

Pituitary basophil microadenomas (corticotroph adenomas)

25
Q

Findings in Alzheimer’s Disease?

A

Macroscopic: thinning of gyri
Microscopic: neurofibrillary tangles, plaques

26
Q

Findings in Parkinson’s disease/DLB?

A

Lewy Bodies (inclusion bodies)

27
Q

Findings in ovarian endometriosis?

A

Macroscopic: chocolate cyst