Pathology Of Diseases Of Immunity Flashcards
(17 cards)
What is the primary function of the immune system?
Protection of the body from infections, foreign agents invasion, self antigens and cancers.
How is the mechanism of immunity categorized?
Into innate immunity and adaptive immunity.
What are the primary lymphoid organs involved in immunity?
Thymus and bone marrow.
Fill in the blank: The organs/tissues involved in immunity are grouped into primary lymphoid organs and _______.
[secondary lymphoid organs]
What is another name for innate immunity?
Innate immunity is also known as native or natural immunity.
What is the primary function of innate immunity?
It is the immediate response to microbes and elimination of damaged cells.
What are the components of innate immunity?
The components include epithelial barriers, phagocytes (neutrophils and macrophages), dendritic cells, natural killer cells, innate lymphoid cells, and the complement system.
What are pathogen-associated molecular patterns?
Cells that participate in innate immunity are capable of recognizing certain components that are shared among related microbes and that are often essential for infectivity.
What are the reactions of innate immunity?
- Inflammation
- Antiviral defense
What is a key difference between innate and adaptive immunity?
Innate immunity does not have memory or fine antigen specificity.
What are the two types of adaptive immunity?
- Humoral immunity
- Cell-mediated (or cellular) immunity
What does humoral immunity protect against?
Humoral immunity protects against extracellular microbes and their toxins.
What is the role of cell-mediated immunity?
Cell-mediated immunity is responsible for defense against intracellular microbes and against cancers.
What are the classifications of disorders of immunity?
The diseases of immunity can be classified into the following: 1. Hypersensitivity reactions 2. Diseases of Autoimmunity 3. Diseases of immunodeficiency 4. Amyloidosis
What are hypersensitivity reactions?
Hypersensitivity reactions refer to an exaggerated response of the immune system to an antigen to which the individual has been previously exposed.
What can cause hypersensitivity reactions?
Hypersensitivity reactions can be caused by both exogenous and endogenous factors.
What usually results from hypersensitivity reactions?
Hypersensitivity usually results from an imbalance between the effector mechanisms of immune responses and the control mechanisms that serve to limit such responses.
