Pathology Review Flashcards

(24 cards)

1
Q

0-4hr post MI

A

minimal change

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2
Q

4-12hr post MI

A

early coagulation necrosis (cytoplasmic eosinphilia), edema, hemorrhage

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3
Q

12-14hr post MI

A

coagulation necrosis & marginal contraction band necrosis

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4
Q

1 to 5 days post MI

A

coagulation necrosis & PMN

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5
Q

5-10 days post MI

A

macrophage phagocytosis of dead cells

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6
Q

10-14 days post MI

A

granulation tissue & neovasculariztion

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7
Q

2weeks to 2 month post MI

A

collagen deposition & scar formation

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8
Q

alpha-feto portein

A

HCC, non-seminatious testicular germ-cell tumors (yolk sac tumor), sometimes in teratoma, and embryonal carcinoma

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9
Q

beta-hCG

A

Trophoblastic tumors (hydratidiform moles); choriocarinoma

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10
Q

Calcitonin

A

Medullary carcinoma of the thyroid

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11
Q

Carcinoembryonic antigen CEA

A

Carcinoma of the lung, pancreas, stomach, breast, colon

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12
Q

Placental alkaline phosphatase (PLAP)

A

seminoma

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13
Q

CA-125

A

Ovarian cancer

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14
Q

CA 19-9

A

Pancreatic cancer

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15
Q

Prostatic acid phophatase

A

Prostate cancer

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16
Q

PSA

A

Prostate cancer

17
Q

S-100

A

Melanoma, neural-derived tumors, astrocytoma, schwannomas

18
Q

Tartrate-resistant phophate

A

Hairy cell leukemia

19
Q

PGF-1

A
Mucocutaneous candidiasis
Adrenal insufficiency
Parathyroid insufficiency
Hepatic failure
alopecia
Pernicious anemia
Gonadal failure;

No HLA

20
Q

PDG-2

A

Thyroiditis
Adrenal insufficiency
T2D;

21
Q

Cortisol Deficiency test

A

Test at highest level (morning cortisol);
Cosyntropin test; (>18ug/dL at 60min is positive result)
Insulin tolerance test;

22
Q

Cushing Diagnostic

A

Dexa suppression test
24hr urine cortisol
Check ACTH (if low, suspect adrenals), (if high –> suppreed

23
Q

Cushing TReatment

A
Excise tumor
Suppress cortisol (Ketoconazole, metyrapone, mitotane)
RU 486 (block glucocorticoids)
24
Q

GH Test

A

glucose tolerance test (75) –> should lower GH

Insulin suppression test –> low glucose should increase GH