pathophys refresher

Question 1

β1 receptor locations & activation effects

Answer 1

• heart
• juxtaglomerular cells

activation: ↑ HR, contractility & conduction, renin release (kidneys)

Question 2

β2 receptor locations & activation effects

Answer 2

• smooth muscle: bronchial, vascular, uterine

activation: relaxation

Question 3

α1 receptor locations & activation effects

Answer 3

• smooth muscles & CNS

activation: contraction

Question 4

α2 receptor locations & activation effects

Answer 4

• sympathetic post-ganglionic neurons

activation: ↓ NE release from nerve terminals