patterns of disease in the liver

Question 1

portal triad/area

Answer 1

made up of:
- hepatic artery
- portal vein
- bile duct
- lymphatics

located at each corner of the hepatic lobule

Question 2

hepatic lobule features

Answer 2

• rough hexagon shape
• ~ 1-2 mm
• portal triad/area in each corner
• hepatocytes run in a radial fashion from portal triad to the central area
• central vein is in the center of the lobule
• ~60% of blood comes from the portal vein and ~40% from the hepatic artery
• blood from portal vein and hepatic artery mix in the sinusoids then drains in the central vein
• blood enters from portal triad and flows to the central vein
• outflow from liver occurs at the central vein
• bile flows from central vein to the bile duct (opposite from blood)
• bile duct lined by cuboidal epithelium