PBL

Question 1

Salmeterol/formeterol

Answer 1

beta 2 agonist, longer duration of action than albuterol (~12 hr)

Question 2

Beclomethasone

Answer 2

corticosteroid used for asthma

Question 3

Budesonide

Answer 3

corticosteroid used for asthma

Question 4

montelukast/zafirlukast

Answer 4

montelukast is AKA singulair

leukotriene receptor antagonist (inhibits CysLT-1)

Question 5

Zileuton

Answer 5

5-LOX inhibitor -> inhibits synthesis of leukotrienes

Question 6

cromolyn

Answer 6

mast cell stabilizer, anti-allergic

Question 7

Methylxanthine

Answer 7

AKA Theophylline

Question 8

what perpetuates the T helper 2 response

Answer 8

IL4

Question 9

IL10

Answer 9

helps TH2

inhibits TH1

Question 10

why are you hypercoagulable when you start warfarin

Answer 10

it first inhibits protein C,

protein C inhibits 8a and 5a

Question 11

what drug may act to increase expression of beta 2 receptors in the lung?

Answer 11

lipocortin

steroids in general i guess

Question 12

eptifibatide

Answer 12

fibrin analog

binds IIb/IIIa and stops platelet aggregation

Question 13

Omalizumab

Answer 13

Binds the Fc portion of IgE, so they IgE doesn’t activate the mast cells