PCM 2 Exam 1 Flashcards
What are the risk factors for type 2 diabetes?
age >45, BMI >25, 1st degree relative with disease, sedentary lifestyle, history of gestational diabetes, hypertension (140/90), dyslipidemia, A1c >5.7 or fasting >100, PCOS, vascular disease
What are the top 3 the clinical presentations for type 2 diabetes?
poylyuria, polydypsia, and polyphagia
What are some other clinical presentations of type 2 diabetes?
rapid weightloss, increased hunger and weight gain, dehydration, fatigue, blurry vision, acanthosis nigricans, <b>impaired healing</b><b>, </b><b>recurrent UTI</b><b>, </b><b>candidal vulvovaginitis</b>, tingling, pain, numbness in extremities</b>
What is the ADA criteria for diagnosis of DM
A1c > 6.5%, fasting glucose > 126, 2 hour glucose > 200 with classic symptoms of hyperglycemia
What should the initial workup after diagnosis of type 2 diabetes include?
fasting lipid, liver enzymes, renal function, microalbuminuria, dilated eye exam, and a foot exam
What should a diabetic foot exam include?
Look for callus/corn formation, breaks in skin, erythema or dryness. Check pulses and sensation including vibratory sensation and monofilament testing
What should be included in therapeutic intervention for type II diabetes?
lifestyle changes, oral metformin or other oral agents, insulin if needed
How often should you check HbA1c for type 2 diabetes management?
every 3 months while adjusting treatment, then every 6 months when stable
What other interventions are recommended for type 2 diabetes management?
smoking cessation, blood pressure, and hyperlipidemia control
What is the ominous octet of hyperglycemia in type 2 diabetes?
increased glucose reabsorption, decreased gluose uptake, decreased incretin effect, increased hepatic glucose production, increased glucagon, impaired insulin secretion, NT dysfunction, increased lipolysis and reduced glucose uptake
What organs or cells are involved in the ominous octet?
kidney, muscle, GI, liver, pancreas X2, brain, fat cells
What are the microvascular diseases associated with type 2 diabetes?
retinopathy (blurred vision), nephropathy (CKD), neuropathy (numbness, tingling)
What are the macrovascular diseases associated with type 2 diabetes?
MI, stroke, peripheral vascular disease
What abnormal infections are increased with type 2 diabetes?
necrotizing fasciitis, malignant otitis externa, etc as well as an increase in other common infections
What are the signs of DKA?
mental changes, nausea, vomiting, abdominal pain, signs of dehydration, Kussmaul respirations, fruity smelling breath
What are the signs of dehydration?
decreased skin turgor, dry oral mucosa, tachycardia, hypotension
What are Kussmaul respirations?
deep, rapid respirations characteristic of acidosis
What is the glucose level requirement for DKA vs HHS (hyperosmolar hyperglycemic state)?
DKA is >200, HHS is >600
Which pathological hyperglycemic state has metabolic acidosis?
DKA. Venous pH <7.3 or plasma bicarb <15
What is the venous pH and serum bicarb in HHS?
venous pH >7.25, serum bicarb >15
Which pathological hyperglycemic state is in ketosis?
DKA. HHS usually has absent or mild ketosis with marked elevation in serum osmolality (>320)
What is the management for DKA/HHS?
admit to hospital. IV fluids, IV insulin, and potassium replacement. DO NOT MANAGE OUTPATIENT
What are the risk factors for Type 1 DM?
genetic susceptibility, possibly environmental trigger
What is the clinical presentation for Type 1 DM?
polydipsia, polyuria, weight loss with hyperglycemia and ketonemia or ketonuria, DKA
- DTRs
- Pulses
- 10-g monofilament pressure sensation PLUS vibration sensation, pinprick sensation, or ankle reflexes
- Little toe
- Ball of the foot under the big toe, middle toe, and little toe
- Heel
- Uvulitis
- prepalatine petechiae
- small red hemorrhages on the soft palate
- conjunctivitis
- malaise or fatigue
- hoarseness
- low-grade fever
- Winter and early spring
- Absence of cough
- Tender anterior cervical lymphadenopathy
- Tonsillar exudate
- Fever
- Tonsillar exudate
- Absence of cough
- Anterior cervical lymphadenopathy
- Age 3-14
- foreign body obstruction
- middle ear fluid
- lack of movement of ossicles
- other obstruction
- Meniere disease
- MS
- Trauma
- Ototoxic drugs
- Barotrauma
- Pain over maxillary sinuses
- Fever
- Pressure when bending over
- steeple sign on xray (subglottic edema)
- caused by parainfluenza, influenza, RSV
- Inspiratory stridor
- GABHS
Rapid onset of symptoms, sore throat, muffled voice, drooling, high grade fever, toxic appearance, stridor
- Columella
- Vestibule
- Bridge
- Vestibule
- Turbinates
- Irregular shape
- Hard
- Tender
- Fixed
- Red, warm, edematous
- Interstital lung disease
- Bronchiectasis
- Pulmonary fibrosis
- Cystic fibrosis
- Lung abscess
- Malignancy
- Inflammatory bowel disease
- Asthma
- COPD
- CHF
- Atelectasis
- Pulmonary fibrosis
- bronchiectasis
- COPD
- Asthma
- Substernal
- Intercostal
- Barrel chest
- Retractions
- pursed lips
- Bronchovesicular (intermediate in intensity and pitch, best heard in 1st and 2nd interspaces ant. and b/w scapula post.)
- Bronchial (loud and high pitched, best heard over manubrium)
- Tracheal
- Wheezes
- Rhonchi
- Stridor
- Pleural friction rub
- jaundice
- cyanosis
- pallor
- nail clubbing
- body habitus
- hydration
- temperature
- Cushing's
- down's syndrome
- hyperthyroid
- myxedema
- increased pressure in RV
- pulmonary hypertension
- pulmonary embolism
- AV dissociation (complete heart block. VT)
- severe heart failure
- constrictive pericarditis, cardiac tamponade, or RV infarction
- Restrictive cardiomyopathy
- constrictive pericarditis
- obstructive RV filling by tricuspid stenosis or Right atrial tumor
- 2 soft, but easily heard
- 3 loud, without a thrill (last grade without thrill)
- 4 loud with a thrill
- 5 loud with minimal contact between stethoscope and chest - thrill
- 6 loud, can be heart without a stethoscope - thrill
+1 barely detectable, nonpitting (2mm)
+2 slight indentation (4mm); 10-15 seconds
+3 indentation (6mm); greater than 1 min
+4 very marked indentation (8mm); 2-5 min
- palpation
- percussion
- auscultation
- aortic or pulmonic stenosis
- mitral or tricuspid regurgitation
- aortic or pulmonic regurgitation
- mitral or tricuspid stenosis
- Aortic sclerosis
- benign murmur
- Hypertrophic cardiomyopathy
- VSD
- tricuspid regurgitation
- mitral valve prolapse
- mitral insufficiency
- pulmonic regurgitation
- mitral stenosis
- Tricuspid stenosis
- Coarctation of the aortia
- Arteriovenous fistulas
- Auscultation
- Percussion
- Palpation
- scars/striae
- dilated veins
- rashes and lesions
- Abdominal distension
- hernias/masses
- surface motion
- pulsations
- 2-3 cm
- >3 cm
- Pyelonephritis
- ureteric colic
- hepatitis
- pneumonia
- pyelonephritis
- ureteric colic
- pneumonia
- ureteric colic
- inguinal hernia
- IBD
- UTI
- gynecological
- testicular torsion
- Ureteric colic
- Inguinal hernia
- IBD
- UTI
- Gynecological
- Testicular torsion
- GERD/PUD
- Gall bladder
- IBD
- Cancer
- Chronic abd pain
- Constipation
- Appendectomy
- Hysterectomy
- C-section
- Ovarian cyst
- gallbladder
ovary
Ovary
Spleen
- long-lasting intestinal obstruction
- intestinal perforation
- mesenteric ischemia
- post-surgical ileus
- peritonitis
- Early bowel obstruction
- lymphoma
- hepatitis
- right-sided heart failure
- amyloidosis
- hematochromatosis
- Hematochromatosis
- Amyloidosis
- Lymphoma
- Blood malignancies
- HIV
- Splenic infarct
- Hematoma
- Mononucleosis
- Fewer than 3 bowel movements/week
- Straining
- Lumpy or hard stools
- Sensation of incomplete defecation
- Manual maneuvering required to defecate
2 - sausage shaped, but lumpy
3 - sausage shaped, but cracks on surface (normal)
4 - sausage or snake-like, smooth and soft (normal)
5 - soft blobs with clear-cut edges (easy to pass)
6 - fluffy pieces with ragged edges, mushy
7 - watery, no solid pieces
- Low back pain
- Tenesmus
- Pain on defecation
- Abdominal pain
- Inability to pass flatus
- Vomiting
- Pelvic exam for females
- Anorectal exam
- use bathroom right away, don't try to hold it
- Increase exercise
- Schedule interrupted time every day for a bowel movement
- Bacterial (15-20%)
- Parasitic (10-15%)
- Food-borne toxigenic
- Drug-associated
- C. Diff
- E. Coli
- Laxatives
- Colchicine
- Quinidine
- Sorbitol
- PPIs
- Alternating b/w constipation and diarrhea, with one dominating over the other
- Intractability to laxatives
- Defecation improves abdominal pain, but does not relieve it
- growth spurt and bone growth
- Development of facial hair, axillary hair
- Increase length of vocal cords
- Facial morphologic changes in the mandible, nose, maxilla, brow, etc
- Increase thyroid size
- Skin changes
2 - Enlargement of testes and scrotum
3 - enlargement of penis, growth of testes
4 - increase size of penis, development of glans, growth
5 - adult genitalia
2 - Breast bud stage with elevation of breast and papilla. Enlargement of areola
3 - further enlargement of breast and areola
4 - Areola and papilla form a second mound above level of breast
5 - Mature stage: projection of papilla only
2 - sparse growth of long, slightly pigmented hair
3 - Darker, coarser, more curled
4 - hair adult in type, but covering smaller area than adult; no spread to medial surface of thighs
5 - adult in type and quantity, with horizontal upper border
- Term deliveries >37 weeks
- Preterm delivery 20-37 weeks
- Abortion <20 weeks
- Live delivery regardless of age"
- Current sexually active
- Number of partners last year or lifetime
- New partner in last 3 months
- Condom use
- History of sexual abuse
- Yearly for abnormal pap smear
- Every 3 years with consecutive normal pap smear
- Every 5 years with consecutive normal Pap smear and negative HPV test
- Endocervix
- Transitional zone
- Squamocolumnar junction
- May have other pregnancy related symptoms like breast tenderness, nausea, etc
- Speculum exam
- If pregnant, transvaginal ultrasonography is recommended
- Urinary frequency or urgency
- Suprapubic pain
- May have hematuria
- Palpate penile shaft and scrotum with thumb and first two fingers
- Palpate inguinal region and examine for hernias
- Examine prostate by palpation on DRE
- Males should perform self testicular exam
- Scrotal mass
- Epididymitis
- Hydrocele
- Testicular cancer or torsion
- UTI
- Varicocele
- Inguinal hernia
- Kidney stones
- May have palpable bulge on affected side
- On PE, invaginate scrotum into inguinal canal and have patient cough or perform Vasalva maneuver to help feel hernia
- Practices
- Prevention of pregnancy
- Protection from STIs and HIV
- Past history of STI
- Multiple partners or partner with multiple partners
- Partners with recently treated STI
- Inconsistent condom use
- Trading sex for money or drugs
- Sexual contact with sex workers
- Meeting anonymous partners on the internet
- Upper genital tract infections
- Infertility
- Chronic pelvic pain
- Cervical cancer
- Chronic infection with HSV, hepatitis, and HIV
- Males penile discharge and dysuria, may be asymptomatic
- Females pelvic pain or mucopurulent vaginal discharge
- Most cases are asymptomatic
- Males penile discharge, pruritus, dysuria
- Females vaginal discharge, bleeding, pain during intercourse, or dysuria
- Secondary: joint pains, fatigue, lymphadenopathy, mucopapular rash
- Latent phase may be asymptomatic
- Tertiary: neurosyphilis (confusion, HA, stiff neck, vision loss)
- Burning, tingling, and pain prior to vesicle appearance
- May be asymptomatic
- Most males are asymptomatic, may have penile discharge
- Females present with foul smelling thin or purulent vaginal discharge, vaginal pruritus, dysuria