PCP medications Flashcards
(50 cards)
Acetaminophen
Tylenol, Tempra
Classification of Acetaminophen
Anti-Pyretic, Non-opioid analgesic
MOA for Acetaminophen
It inhibits the synthesis of Prostaglandins in the CNS blocking the generation of pain impulses.
Works on the Hypothalamus heat regulating center to increase vasodilation resulting in increased blood flow to the skin allowing the release of heat
Contraindications of Acetaminophen
Hypersensitivity to Yellow 5, Saccharin, Aspartame, Sugar, Alcohol
Active liver disease or hepatic impairment
Chemotherapy
Indications for Acetaminophen
Mild pain (Non-Opioid Analgesic)
Reduction of fever (Anti-Pyretic)
Dosage of Acetaminophen
Adult 975mg Do Not repeat
Pediatric 15mg/kg up to 975mg Do Not Repeat
EMS considerations for Acetaminophen
document PT temperature before and after administration
If PT has not received the max dose in the last 4 hrs administer the remaining dose. Do Not Administer if PT has had max dose in the last 4 hours
Toxicology and Side Effects of Acetaminophen
Toxic at 150mg/kg or 7.5g
Renal failure with High dose or chronic use
Hepatic Damage
Acetylsalicylic acid
ASA, Aspirin, Bufferin
Classification of Acetylsalicylic Acid
Anti Platelet aggregator, Anti-Pyretic, Analgesic, Non Steroidal Anti-inflammatory drug (NSAID)
MOA of Acetylsalicylic Acid
Blocks Thromboxane which starts the clotting process
Inhibits the production of prostaglandins
Indications for Acetylsalicylic Acid
Acute Coronary Syndrome (ACS)
Contraindications of Acetylsalicylic Acid (7)
Hypersensitivity to salicylates/NSAIDS
Unable to follow commands
Active ulcer disease or GI hemorrhage
Bleeding Disorder
Pregnancy (especially 3rd trimester)
Children under 15
ASA induced Asthma
Dosage for Acetylsalicylic Acid
160mg (162mg) PO Chewed, Do Not repeat within 24 hrs
Onset 1-2 hrs
Duration 4-5 hrs
Side Effects of Acetylsalicylic Acid (4)
GI irritation
Nuasea vomiting
Tinnitus
Increased risk of bleeding
EMS Considerations for Acetylsalicylic Acid (5)
Confirm that PT took ASA properly by Dispatch or alternative First responder instructions before Administering EMS dose
ASA must still be administered if daily prescribed dose has been taken
Diabetics at risk for developing hypoglycemia
Reye’s syndrome: fatal disease characterized by edema of the brain, hypoglycemia, fatty infiltration and liver dysfunction. And is the reason for children under 15 being a contraindications
Dextrose in water
D10W, D25W, D50W
Dextrose in water Classification
Caloric Agent
Dextrose in Water MOA
- increase blood sugar to normal in hypoglycemia
- Hypertonic solution producing a transient movement of water from interstitial spaces into the venous system (osmotic diuretic)
Indications for dextrose in water
- severe hypoglycemia
- Head injury with symptomatic hypoglycemia (half dose)
- Stroke with symptomatic hypoglycemia (half dose)
Contraindications for dextrose in water
- allergy to corn
- hyperglycemia
- hypersensitivity to dextrose solution
- relative contraindications- intracranial hemorrhage (half dose)
Adult dosage for dextrose in water (3)
- 25g D50W SIVP/IO q 5 min prn, titrate to BGL >/= 4.0 mmol/L or PT improvement to max 50g
- Suspected stroke: 12.5g D50W SIVP/IO q 5 min prn, titrate to BGL = 3.0mmol/l or PT improvement to max 50g
- suspected head injury: 12.5g D50W SIVP/IO q 5min prn, titrate to BGL = 4.0mmol/L or PT improvement max 50g
side effects of dextrose in water (4)
- rebound hyperglycemia
- May aggravate hypertension and CHF
- may cause neurological symptoms in alcoholic PT
- Wernicke’s encephalopathy/ Korsakoff’s syndrome