Pearls Flashcards

(38 cards)

1
Q

First step in treatment of colonic pseudo obstruction?

Second step?

A

First step: conservative measures with NPO, IVF, rectal tube

Second step: 2mg neostigmine over 3 min in a monitored bed with atropine ready in case of bradycardia

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2
Q

Repair of an umbilical hernia should be differed until what age?

A

5years old

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3
Q

Treatment for colonic volvulus?

A

NPO, NGT, IVF, Abx, Foley

Then rigid or flexible sigmoidoscopy to de-torse a sigmoid volvulus. Leave a tube while bowel prepping for OR

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4
Q

Treatment for radiation injury to small or large bowel

A

Low residual diet that is low fat, lactose and gluten free. Steroids, IVF, and abx may be helpful. Sucralfate enemas are the most effective medical therapy

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5
Q

Nonoperative techniques to lowering intracranial pressure?

A

Raise head of bed, Mannitol, hyperventilation, sedation and paralysis

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6
Q

Amsterdam criteria for HNPCC?

A

3-2-1, 50-25-5

3 relatives with HNPCC related cancers, 2 successive generations, one relative under 50 years old, start colonoscopy at 25 or 5 years before age of relative at diagnosis

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7
Q

Screening and treatment for Familial adenomatous polyposis (FAP)?

A

Colonoscopy and EGD starting at age 12. Routine CT abdomen every 12 months as well given possibility of retroperitoneal Desmond tumors.

Colectomy deferred until 17 or 18 unless polyps appear earlier. Prophylactic total colectomy with ileorectal anastomosis should be performed once polyps appear. Will still need surveillance of rectum every 5 years

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8
Q

Screening and treatment for HNPCC?

A

Colonoscopy starting at 25 or 5 years younger than age of youngest relative at diagnosis.

Surgery once cancer or adenomas with satellite instability are found or if patient cannot adhere to surveillance. Total abdominal colectomy with ileorectal anastomosis or total proctocolectomy with ileal pouch anal anastomosis are the options. Hysterectomy indicated in female patients who have finished child bearing.

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9
Q

What is Nigro protocol?

A

4 weeks of 5-FU, mitomycin C, and radiation (3000-4800 rads)
If inguinal nodes are positive then they are included in radiation field

6 weeks of rest

Re-evaluate and re-biopsy

If negative then start surveillance (proctoscopy with biopsy every 3 months for 2 years, then every 6 months for 3 years, then annually)
If positive then give second dose of chemorads

6 weeks of rest

Re-evaluate and re-biopsy

If positive then APR

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10
Q

Treatment for anal squamous carcinoma and adenocarcinoma?

A

Squamous carcinoma: nigro protocol

Adenocarcinoma: if not invading sphincters then WLE, if invading sphincters then nigro protocol

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11
Q

If focal nodular hyperplasia is suspected diagnosis of liver lesion, what tests to order?

A

Triple phase CT abdomen will show contrast-enhanced central scar and spoke wheel appearance.

Confirm with sulfur-colloid nuclear medicine scan which will show a cold module

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12
Q

Which two tumor markers differentiate between primary malignant and metastatic liver lesions?

A

Primary hepatocellular carcinoma: Elevated AFP

Metastatic lesion: elevated CEA

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13
Q

What do malignant liver lesions look like on triple phase CT?

A

Look hypervascular on arterial phase but washes out quickly and look hypovascular on venous phase

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14
Q

Treatments of liver cyst caused by entamoeba histolytica and echinococcus?

A

Entamoeba histolytica: flagyl followed by chloroquine if no improvement in first 3 days

Echinococcus: Antihelminthics (albendaxole, mebendazole) and surgery

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15
Q

How are the diagnoses of a hydatid cyst and amoebic cyst confirmed?

A

Hydatid: Serology tests such as ELISA or immunoblotting can be 80-100% sensitive

Amoebic: Microscopic identification of cysts and trophozoites in the stool

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16
Q

Management of ascitis?

Medical treatment for hepatic encephalopathy?

A

Ascitis: low sodium diet, spironolactone, lasix, therapeutic paracentesis, TIPS

Encephalopathy: rule out other causes (UTI etc), restrict protein in diet to 1 gm/kg/day, lactulose, oral neomycin can reduce nitrogen producing bacteria

17
Q

What are the 5 components of the Child’s-Pugh score?

A

Albumin, bilirubin, INR, Ascites, encephalopathy

18
Q

Treatment for bleeding esophageal varices?

A

Start octreotide, vasopressin, and PPI drips. EGD with banding (sclerotherapy second line option)

If fails then place minnesota tube x48 hrs

If fails then perform TIPS

19
Q

Management of asymptomatic pancreatic pseudocyst?

Management of symptomatic management pseudocyst?

A

Asymptomatic: observe for 6 weeks and then repeat CT. If stable or decreases in size then continue to observe. If increases in size, especially above 6cm then treat like symptomatic pseudocyst.

Symptomatic: Do ERCP to determine if pseudocyst communicates with pancreatic duct. If no communication then place percutaneous drain (send fluid for amylase, CEA, mucin, and CA 19-9). If communication then surgical drainage.

20
Q

What is the preoperative therapy before thyroidectomy for conditions causing hyperthyroidism?

A

Preop PTU for 2 weeks, Lugols solution for 10 days, and propranolol

21
Q

What is the medical prep to optimize patient for adrenalectomy for pheochromocytoma?

A

Phenoxybenzamine 10mg PO TID given until patient has orthostatic hypotension. Propranolol if patient remains tachycardic.

In the OR nitroprusside, esmolol, neosynephrine, and lidocaine drips must all be available

22
Q

What is the medical management of aldosteronoma leading up to surgery?

A

Spironolactone and potassium supplementation to correct hypokalemia, and verapamil or lisinopril to treat hypertension.

23
Q

What gastrin level is diagnostic for Zollinger Ellison syndrome? What level is diagnostic after a secretin stimulation test?

A

Gastrin > 1000 or gastrin > 200 checked in 5 min intervals for first 30 min after secretin stimulation test. Patient must be off PPI for 7 days prior to testing.

24
Q

What is treatment of unresectable gastrinoma?

A
ZAP-5
Zanosar (streptozosin)
Adriamycin (doxorubicin)
PPI
5-FU

Pyloromyotomy and vagotomy is also an option

25
When should prophylactic thyroidectomy be performed in MEN 2A patients and MEN 2 B patients?
MEN 2A: 6 years old | MEN 2B: infancy
26
What are the chemotherapy regimens for Hodgkins and non-Hodgkins lymphomas?
Hodgkins: CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) Non-Hodgkins: MOAP (methotrexate, vincristine, asparaginase, prednisone)
27
What is the treatment for soft tissue sarcoma?
Resection with 2 cm margins. If positive margins along major nerves then postop XRT with 6000 rads. Ifosfamide and doxorubicin for disseminated disease.
28
What is the surveillance after soft tissue sarcoma resection?
PE and CXR every 3 months and CT chest every 6 months
29
What size cutoff is used for medical vs surgical management of ectopic pregnancy?
<4 cm: methotrexate | >4 cm: salpingectomy or salpingectomy
30
Treatment for simple adnexal cyst? Treatment for a simple ovarian cyst?
Treat with OCP and repeat U/S in 6 months. Laparoscopic cystectomy if persistent. <5cm observe and repeat U/S in 6 weeks >5cm or persistent for >6weeks then cancer work up and salpingectomy-oophorectomy for premenopausal woman and TAH-BSO for post menopausal woman
31
What is the adjuvant therapy for ovarian cancer?
Doxorubicin, cisplatin, cyclophosphamide, and whole abdominal radiation
32
What is the work up for a testicular lesion?
U/S, CXR, and tumor markers including HCG, AFP, LDH. If CXR positive then also a CT chest. Seminoma: high HCG Non-seminoma: high HCG and high AFP Diagnosis is confirmed with orchiectomy (do not biopsy mass)
33
What is the treatment for seminoma and non-seminoma after orchiectomy performed to confirm diagnosis?
Seminoma: if tumor markers still elevated after orchiectomy then chemo (cisplatin, bleomycin, and etoposide) and radiation (2500-3500 rads). Positive nodes get irradiated. If nodes negative and tumor markers go down after orchiectomy, chemo isn’t needed but ipsilateral para-aortic nodes still get radiation Non-seminoma: not radiosensitive so same as above but no radiation. Positive nodes need lymphadenectomy
34
Describe the biopsy for diagnosing Hirschsprung’s disease?
Full thickness suction rectal biopsy 2 cm above the denture line
35
Minimum FEV1 for pneumo extort, lobectomy, and wedge resection?
Pneumonectomy: FEV of 2L Lobectomy: FEV 1L Wedge resection: FEV 0.6L
36
What is the dose of heparin given to a patient that comes in with a threatened limb from acute limb ischemia?
100u/kg bolts and then 15u/kg/hr drip.
37
What are the treatments for neurogenic, venous, and arterial thoracic outlet syndromes?
Neurogenic: 6 weeks of physical therapy and if no improvement then anterior scalenectomy and 1st rib resection Venous: thrombolytics and heparin bridge to Coumadin for at least three months as well as 1st rib resection Arterial: subclavian to a axillary bypass
38
How is an SMA embolectomy done - in a nutshell?
Transverse arteriotomy and passing a 4Fr fogarty proximal and distal until good forward and back bleeding