Pedi Endocrine Flashcards

(39 cards)

1
Q

Endocrine System

Human Growth Hormone

A

somatotropin
naturally occuring substance secreted by pituitary gland
important for normal growth, development, cellular metabolism
deficiency prevents somatic growth throughout body

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2
Q

Diabetes Mellitus

A

partial or complete metabolic deficiency of insulin

contributes to development of cardiovascular disease, hypertension, renal failure, blindness, stroke

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3
Q

Type 1 Diabetes

Risk factors

A

Genetics

toxins and viruses destroy beta cells

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4
Q

Type 2 Diabetes

Risk factors

A

genetics

obesity, physical inactivity, high triglycerides (greater than 250), hypertension

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5
Q

Hypoglycemia

Manifestations

A

less than 60mg/dL

Autonomic nervous system responses rapid onset:
hunger, lightheadedness, shakiness
headache
anxiety/irritability
pale, cool skin
diaphoresis
normal/shallow respirations
tachycardia/palpitations
impaired cerebral function gradual onset:
strange/unusual feelings
decreasing level of consciousness
difficulty in thinking and inability to concentrate
change in emotional behavior
slurred speech
headache/blurred vision
seizures/coma
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6
Q

Hypoglycemia

Treatments

A

fast acting, simple carbs (15 g)
4 oz juice or regular soda; 8oz of milk; 3 glucose tabs; 1 tube glucose gel; 1 pack of fruit snacks

observe for 10 mins, recheck, goal is greater than 70. exceeds 70 = follow up with solid food snack or next meal.
if no improvement = repeat until above 70

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7
Q

Hyperglycemia

Manifestations

A

greater than 250mg/dL

thirst
polyuria (early)
oliguria (late)
N&V, abdominal pain
warm, dry, flushed skin with poor turgor
dry mucous membranes
confusion
weakness
lethargy
weak pulse
diminished reflexes
rapid, deep repirations with acetone/fruity odor due to ketones (Kussmaul respirations)
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8
Q

Hyperglycemia

Treatment

A

give water
insulin
test urine for ketones
call MD if symptoms progress

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9
Q

Diabetes

Laboratory Tests confirming DM DX

A

8 hour fasting blood glucose of 126 mg/dL or more
Random blood glucose of 200 mg/dL or more with classic signs
Oral glucose tolerance test of 200 mg/dL or more in 2 hr sample

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10
Q

Client Education

Fasting Blood Glucose

A

ensure fasting for 8 hr prior to blood draw

antidiabetic meds should be postponed until after level is drawn

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11
Q

Client Eduation

Oral glucose tolerance test

A

consume balanced diet for 3 days prior to test
fast for 8 hr prior to test
fasting level drawn at start
consume specific amount of glucose
levels drawn every 30 min for 2 hr
the child must be assessed for hypoglycemia throughout procedure

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12
Q

Glycosylated hemoglobin (HbA1c)

A

expected range: 4%-6%
target for child w/ DM: 6.5%-8%
target goal: less than 7%

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13
Q

Self-monitored blood glucse (SMBG)

A

before meals and at bedtime

journal record: time, date, serum glucose level, insulin dose, food intake, events that may alter (activity, illness)

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14
Q

Diabetes

Nursing Care

A
nair care
foot care
prevention of infection
nutritional guidelines - 15g of carbs=1 carb exchange
techniques for SMBG
exercise plan
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15
Q

Diabetes

Sick Plan

A

Monitor blood glucose every 3 hr
continue to take insulin or oral anti-diabetic agents
encourage sugar-free, non-caffeinated liquids to prevent dehydration
meet carb needs by eating soft foods if possible, consume liquids that are equal to usual carb content
test urine for ketones q3h
rest

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16
Q

Diabetes

Sick Plan

Call MD

A
blood glucose greater than 240mg/dL
fever is greater than 38.9/102, fever does not respond to acetaminophen or lasts longer than 12 hr
positive ketones in urine
disorientation or confusion
rapid breathing
vomiting occurs more than once
diarrhea occurs more than 5 times or for longer than 24 hrs
liquids cannot be tolerated
illness lasts longer than 2 days
17
Q

Diabetes

Insulin pumps

A

regular insulin, programmed amt on consistent basis
alarm will sound: pump failure, occluded tubing, no insulin,
alarm will not sound if needle becomes dislodged

18
Q

Diabetes

Insulin injections

A

2+ times per day; mixing insulin: rapid-acting and intermediate acting
rotate injection site (prevent lipohypertrophy) within one anatomic site to prevent changes in absorption rate

19
Q

Rapid Acting Insulin

A

Name: Insulin lispro (Humalog)
Onset: less than 15 min
Peak: 0.5-1 hr
Duration: 3-4 hr

20
Q

Short Acting Insulin

A

Name: Regular insulin (Humulin R)
Onset: 0.5-1 hr
Peak: 2-4 hr
Duration: 5-7 hr

21
Q

Intermediate Acting Insulin

A

Name: NPH insulin (Humulin N)
Onset: 1-2 hr
Peak: 4-12 hr
Duration: 18-24 hr

22
Q

Long Acting Insulin

A

Name: Insulin glargine (Lantus)
Onset: 3-4 hr
Peak: none
Duration: 10.4-24 hr

23
Q

Insulin

Client Education

A

observe child and parent drawing up insulin
do not mix glargine (Lantus) with other insulins due to incompatibility
rotate injection sites to prevent lipohypertrophy
inject at a 90degree angle (45degree if thin)
do not aspirate blood
draw up shorter-acting insulin into syringe first and then longer-acting insulin

24
Q

Diabetic Ketoacidosis

A

life threatening condition defined by hyperglycemia, greater than 300mg/dL
caused by missed dose of insulin or poor insulin administration technique
causes a breakdown of body fat for energy and an accumulation of ketones in blood and urine
onset is rapid and mortality is high

25
Diabetic Ketoacidosis Causes
``` insufficient insulin (usually failure to take appropriate dose) acute stress (trauma or surgery) poor management of acute illness ```
26
Diabetic Ketoacidosis Nursing Actions
Admit to ICU provide rapid isotonic IV fluid (0.9% sodium chloride) to maintain perfusion to vital organs, large quantities may be required, monitor for fluid volume excess follow with IV hypotonic fluid (0.45% sodium chloride) to continue replacing losses to total body fluid When serum glucose levels approach 250 mg/dL add glucose to IV fluids to minimize risk of cerebral edema associated with drastic changes in serum osmolality admin Regular insulin 0.1 unit/kg as an IV bolus then follow with continuous infusion of regular insulin at 0.1 unit/kg/hr
27
DKA Monitor Glucose
monitor glucose levels hourly
28
DKA Monitor Potassium
monitor serum potassium initially will be elevated, insulin will shift potassium into cells and child needs to be monitored for hypokalemia = provide potassium replacement therapy in all replacement IV fluids, make sure urinary output is adequate before administering K normal range = 3.7-5.2
29
DM Long-Term Complications
``` nephropathy retinopathy neuropathy cardiovascular disease altered thyroid function limited mobility of small joints ```
30
Growth Hormone Deficiency
Human Growth Hormone (GH) somatotropin, secreted by pituitary gland GH is important for normal growth, development and cellular metabolism
31
Growth Hormone Deficiency Hormones that Assist GH
Adrenocorticotropic (ACTH) Thyroid stimulating hormone (TSH) Gonadotropins, Follicle stimulating hormones (FSH) Luteinizing Hormone (LH)
32
Growth Hormone Deficiency Risk Factors
structural factors (tumors, trauma, structural defects, surgery) heredity disorders other pituitary hormone deficiencies (deficiencies of TSH or ACTH) idiopathic
33
Growth Hormone Deficiency Manifestations
``` short in stature delayed epiphyseal closure increased insulin sensitivity delayed dentition underdeveloped jaw delayed sexual development ```
34
Growth Hormone Deficiency Diagnostics - GH Stimulation
testing done if low level of IGF-1 and IGFBP-3 and short stature draw baseline blood between 0600 and 0800 admin meds that trigger release of GH (arginine or GH-releasing hormone) obtain blood sample every 30 min for 3hr period following med admin NPO 10-12 hrs before test limit activity 10-12 hr before test
35
Growth Hormone Deficiency Diagnostics - Radiological Assessments
assess skeletal maturity by comparing epiphyseal centers on x-ray to age-appropriate published standards perform general skeletal survey in children under 3, or survey hands and wrists in older children assist in positioning
36
Growth Hormone Deficiency Diagnostics - CT scan, MRI, skull x-rays
identify tumors or structural defects monitor during procedure sedate provide emotional support
37
Growth Hormone Deficiency Diagnostics - evaluation of growth curve
accurately obtain and plot height and weight assess height velocity or over time determine height-to-weight relationship project target height in context of genetic potential
38
Growth Hormone Deficiency Nursing Care
height and weight measured and marked on growth chart bone age usually matches height children less than 3 years measure every 6 mos and greater than 3 measure every year monitor effectiveness of GH replacement admin other hormone replacements (thyroid hormone) provide psychosocial support and reassure lack of cognitive delays or deficits
39
Growth Hormone Deficiency Somatropin
replacement for human growth hormone admin via subcutaneous injections use cautiously in children receiving insulin