Pediatric GI disease

Question 1

GERD in children

Answer 1

Passage of gastric contents into the esophagus from the stomach
through the lower esophageal sphincter (LES)

Young infants have increased intraabdominal pressure due to their inability to sit upright

Question 2

____ & __ (medication) GI are safe to neonates and children

Answer 2

H2 receptor antagonist
PPI

Question 3

____ (medication) safe in pregnancy

Answer 3

Esomeprazole

Question 4

Non-Pharmacological Strategies to treat GERD

Answer 4

Thickened Feeds
Avoiding Cow’s Milk Protein
Infant positioning: Left lateral positioning or head elevation after feeding

Question 5

H2 antagonist dosage for children to treat GERD

Answer 5

Infants 1-3 months: 0.5mg/kg/dose once daily for up to 8 weeks
* Infants >3months-1year: 1mg/kg/dose twice daily for up to 8 weeks (max dose 40mg/day)
* Children & Adolescents: 1mg/kg/dose every 12h (max dose 40mg/day)

Question 6

PPI dosage for infant to treat GERD

Answer 6

<30kg:15mgoncedailyforupto12weeks * >30kg:30mgoncedailyforupto12weeks

Question 7

Infantile Hypertrophic Pyloric Stenosis

Answer 7

Obstruction of the pyloric sphincter that is a result of hypertrophy of the sphincter muscle