Pediatrics Review* Flashcards

1
Q

___ closes functionally at birth when LA pressure is > than RA pressure.

  • Any change in ___ can cause flow to reverse
  • Anatomically closes in ___
A

PFO
-pressure gradient
3-6 months

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2
Q

____ artery comes off the aorta before the ___.

  • Important when placing an A-line
  • If we place a right radial a-line measuring ___
  • If we place a left radial a-line measuring ___
A

Right innominate artery
PDA
-pre-ductal oxygen
-post-ductal oxygen

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3
Q
  • Babies have a higher ___ hence their increased oxygen consumption
  • Limited ___ stores
  • ___ dominant
A
  • metabolic demand
  • catecholamine
  • PSNS
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4
Q

Babies have ____ need really good pre-oxygenation, less safe apnea time.

A

decreased FRC (25, adult is 40)

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5
Q
  • In newborn blood loss >___ may not be tolerated - fetal Hgb
  • At ___ the baby will have a physiologic anemia due to fetal Hgb dropping off and adult Hgb increasing
  • Hgb considered in context….neonate with Hgb of ___ concerning because majority is fetal Hgb = serious - meanwhile at ___ this Hgb is expected
A

> 10-15%
2-6 months
10
2 months (10-12)

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6
Q
  • HBF ___ in first months of life.
  • CYP450 system ___ functional at birth.
  • Want to give drugs that don’t rely on hepatic metabolism ??
  • Infants have minimal glycogen stores may need maintenance fluid with?
A
  • decreased
  • 50%
  • atracurium, cisatracurium
  • dextrose
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7
Q
  • Infants have a high TBW content drugs that are water-soluble (?) will have a larger ___
  • Minimal ___ - Less fat for redistribution of drugs = higher availability
A

Muscle relaxants
volume of distribution
fat stores

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8
Q

General Rule:

  • Most PO/IV meds prolonged elimination half time in ___ (decreased dosing intervals)
  • Shortened elimination half time in ___
  • Normal elimination half time as ?
A
  • infants
  • children (2-12 years)
  • child approaches adulthood
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9
Q

___ closure after birth is functional, not anatomical.

  • Ductus constricts and closes based on levels of ___, ___, ___
  • So if the baby gets ___ and ___ this will pop open - this will cause a large % of blood flow to bypass the lungs
  • PDA closes anatomically btw ___. ___ will have more delayed closure.
A

PDA

  • O2, CO2, prostaglandins
  • acidotic and hypoxic
  • 2-6 weeks
  • Premies
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10
Q

View of the pediatric airway is usually almost always better with a ?

A

straight blade

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11
Q

Fluid Choices:

  • For children less than 2 years old use a ___ filled with ___ at a time
  • If greater than 2 years old use ___ with only ___ up at a time
A
  • buretrol filled with 25-100 mL

- mini gtt with only 500 mL bag

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12
Q

Pediatric Differences:

  • Babies and children adjust CO and BP by ___. They have poor ___.
  • Higher ___ demand.
  • ___ thus have limited ability to handle fluid overload or increased SV.
A
  • HR
  • contractile strength
  • metabolic
  • Noncompliant LV
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13
Q
-In regards to respiratory peds patients known to have ~
small \_\_\_/highly \_\_\_
-Depress ventilation??
-Decreased \_\_\_ muscle fibers
-Smaller number of \_\_\_
A
  • small diameter/highly compliant airways
  • hypoxia and hypercapnia
  • Type 1
  • alveoli
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14
Q

Babies have decreased ___ need really good pre-oxygenation due to less safe apnea time

  • Ideal position for intubation of the very young child/neonate?
  • If suspect traumatic intubation give?
A

FRC
(babies = 25, adults = 40)
-Neutral or slightly flexed
-Decadron or racemic epinephrine

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15
Q

Neonates ~ ECF = ___ of body weight, TBW = ___
@ 2 years ~ ECF = ___ of body weight
*Neonates are at increased risk for ___ = always concerned about ___

-Normal kidney function at ___

A
40%, 78%
20%
*evaporative losses 
dehydration 
-6 months
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16
Q

Hepatic - impaired conjugation - jaundice

*___ reaction, ___ reaction (example: morphine relies on this for metabolism) less mature in babies

A

Phase 2 reaction, conjugation reaction

17
Q
  • Opioids will decrease the ___ requirement
  • Decrease HR and cause respiratory depression?
  • Prefer to give?
A
  • MAC
  • Opioids
  • Fentanyl
18
Q

Succinylcholine dose in pediatric population - IV? IM?
Always administered with?
*Appropriate time to administer succ to a child less than 5 years old??

A

1-2 mg/kg IV
4-5 mg/kg
Atropine
*laryngospasm and RSI (can also use high dose rocuronium)

19
Q

Reversals for peds??

  • Equipment need at least __ suction catheters, __ blade is best, and ___ (used during induction to listen to heart tones)
  • Nasal or oral airway?
A

Neostigmine 0.02-0.05 mg/kg with Glycopyrrolate 0.02 mg/kg
Edrophonium 0.3-1 mg/kg with Atropine 0.02 mg/kg
-2
-Miller
-Precordial stethoscope
-Oral preferred

20
Q

Cuffed ETT worried about tracheal mucosa pressure from ___ of ETT.

  • Need to do a leak test (close APL and provide PP ventilation to hear)
  • arbitrary value of leak at ___
  • if patient has a leak at ___ need larger uncuffed ETT or inflate cuff
  • if patient does not have a leak at ___ need smaller uncuffed ETT or deflate the cuff
A

external diameter

  • less than 25 cmH2O (20-30)
  • less than 20 cmH2O
  • greater than 40 cmH2O
21
Q
  • For maintenance requirement? (not used for fluid replacement) (used more in ??)
  • For deficits and third space losses?
A

-D5 in 0.45%
neonates and infants
-LR

22
Q
  • During mask ventilation keep your fingers off ___
  • Always keep equipment one size larger and one size smaller than anticipated
  • After tracheal intubation you must always check for?
  • Need to consider loose teeth in?
A
  • soft tissue
  • a leak
  • school age children
23
Q

Preop physical exam:

  • ask for birth history for kids ___ (were they premature, etc.)
  • ___ = want details about the birth and mother’s health status (diabetes, preeclampsia, HTN)
A
  • less than or equal to 5 years old

- neonates

24
Q

Premedicate with ___ or ___
*Premedication
-___
PO 0.25-1 mg/kg, max?, nasal/SL 0.2 mg/kg, IM 0.1-0.15 mg/kg max?
-___ good for uncooperative kids PR/IM = 5-10 mg/kg

A
Benzos or opioids
-Midazolam 
20 mg
7.5 mg 
-Ketamine
25
Q

Pediatrics Inhalation Induction:

  • Mask with ___ and ___, sequentially adding ___ until unconscious but still breathing on their own
  • After unconscious ___
  • Preoxygenate (turn off ___, decrease ___ and ___). Kids obstruct easily need ___
  • Administer MR and atropine > when paralysis achieved = sevo off and intubate. When begin maintenance make sure?!?
A
  • Oxygen-30%, N2O-70%
  • sevoflurane (turn all the way up! second gas effect!)
  • start IV
  • N20, decrease sevo, and 100% FIO2
  • oral airway
  • agent turned down!!
26
Q

*Maintenance = careful with ___
*Emergence:
-Assess for muscle strength by?
-___ easily, clear ___
-Common in peds? Preop ___ may attenuate this.
(kid looks like their in pain but their not)

A
  • opioids
  • leg strength, lifting legs
  • laryngospasm, secretions
  • emergence delirium
  • versed
27
Q

-In all kids with blocks max of ?

Emergence Recovery = 2 Major Events:

  • Treat laryngospasm?
  • Treat post-intubation croup?
A
  • 20 mL
  • Jaw lift, positive pressure, succ 0.5-1 mg/kg IV
  • Decadron 0.25-0.5 mg/kg IV or Racemic Epi
28
Q

Titrate VAs slowly, insufficient surface active proteins (IRDS), postop apnea/bradycardia risk, minimal glycogen stores (at risk for hypoglycemia and acidemia), lower albumin levels, can’t handle large protein loads, renal insufficiency (CrCl decreased, impaired sodium retention, impaired glucose excretion, impaired bicarb reabsorption)?

  • Decreased??
  • Lower?
  • Prolonged?
A

Premature Infant

  • Stress Tolerance
  • Anesthetic requirement
  • half life
29
Q

Difficult airway with ___!!!

  • ___ neck with irregular ___
  • potential for ___
  • large ___
  • ___ may cause inadequate leak with ETT
  • Congenital Cardiac Malformations
A

Trisomy 21

  • short, dentition
  • atlanto-occipital instability
  • protruding tongue
  • subglottic stenosis