Pedigree

Question 1

Dominant Pattern of inheritance

Answer 1

Disease is found vertical = in every generation

it does not matter if somebody dies

Question 2

Recessive Pattern of inheritance

Answer 2

Disease is found in a horizontal pattern = might be seen in multiple offspring from the same cross

Carrier = heterozygotes, phenotypically normal but have a recessive “disease” allele

See lec 2 slides for pic

Question 3

Proband

Answer 3

Individual who was first diagnosed with the disease in the family

Question 4

Recessive alleles often produce

Answer 4

non functional proteins (loss of function) see lec slides 2

Question 5

Wild type Allele

Answer 5

See lec slide 2