Pedigree

Question 1

Pedigree

Answer 1

a pictorial representation of a family history that outlines the inheritance of 1 or more characteristics

Question 2

Proband

Answer 2

the person from whom the pedigree is initiated

Question 3

Autosomal Recessive Traits

Answer 3

1. usually appears in both sexes w/ equal frequency
2. Tends to skip generations
3. Affected offspring are usually born to unaffected parents
   4.When both parent are heterozygous approximately 1/4 of offspring among the children of consanguineous mating

Question 4

Autosomal Dominant Traits

Answer 4

1. Usually appears in both sexes w/ equal frequency
2. Both sexes transmit the trait to their offspring
3. Does not skip generations
4. Affected offspring must have an affected parent unless they possess a new mutation
   5.When one parent is affected (heterozygous) & the other parent is unaffected, 1/2 of offspring will be affected
5. Unaffected parents do not transmit the trait

Question 5

X-Linked Recessive Traits

Answer 5

1. Usually more males than females affected
   2.Affected sons are usually born to affected to unaffected mother; thus the traits skips generations
2. Approximately half of a carrier (heterzygous) mother’s sons are affected
3. Never passed from mother to son
4. All daughters of affected fathers are carriers

Question 6

X-Linked Dominant Traits

Answer 6

1. Both males and females are usually affected; often more females than males are affected
2. Does not skip generations. Affected sons must have an affected mother; affected daughters must have either an affected mother or father
3. Affected fathers pass the trait to all their daughters
4. Affected mothers (if heterozygous) pass the trait to half their sons and half their daughters