peds- derm pearls Flashcards

(33 cards)

1
Q

how can you differentiate rosacea from acne vulgaris

A

rosacea does not have comedomes

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2
Q

this skin condition is characterized by areas of open comedones (blackheads) w/ incomplete blockage, closed comedones (whiteheads) w/ complete blockage, papules, pustules, nodules, and cysts, that may result in scarring

A

acne vulgaris

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3
Q

treatment of acne vulgaris involves

A

Most acne- topical retinoids.
Cystic acne- tetracyclines, then oral retinoids - isotretinoin (causes dry lips, liver damage, increased triglycerides/cholesterol, pregnancy category X). Must obtain 2 pregnancy tests prior to starting it and monthly while on it.

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4
Q

what is androgenic alopecia?

A

gradual conversion of terminal hairs –> indeterminate –> vellus hair

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5
Q

Which autoimmune disorder is most commonly associated with patchy hair loss on the scalp?

A

Alopecia Areata

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6
Q

Which type of alopecia is characterized by sudden, diffuse hair loss and is often triggered by stress or illness?

A

Telogen Effluvium

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7
Q

Androgenetic alopecia is typically a clinical diagnosis, but what labs would you order to work-up a cause?

A

hormones - testosterone, DHEA, prolactin

treatable - thyroid (TSH), anemia (CBC), autoimmune (ANA)

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8
Q

what is the treatment for androgenic alopecia?

A

Topical: Minoxidil/Rogaine 2%, %5; *hair loss first before regrowth
Finasteride 1 mg ⇒ inhibits T and DHT
Spironolactone ⇒ blocks DHT

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9
Q

what is the common location of atopic dermatitis? what type of sensitivity rxn is it?

A

flexor surfaces ⇒ antecubital and popliteal folds

IgE, type 1 hypersensitivity
Infant- face and scalp
Adolescent- flexural surfaces

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10
Q

describe the presentation of atopic dermatitis

A

Pruritic, eczematous lesions, xerosis (dry skin), and lichenification (thickening of the skin and an increase in skin markings).

*Atopic association ⇒ asthma, etc.

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11
Q

what is the treatment for atopic dermatitis?

A

Review medications: OTX, RX, homeopathic, hot water, humidifier
Antihistamine (Hydroxyzine or Benadryl)
Topical or oral steroids
PUVA Phototherapy

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12
Q

what is the treatment of contact dermatitis?

A

Avoid aggravating agents
Antihistamine (Hydroxyzine or Benadryl)
Zinc oxide (diaper rash)
Topical (triamcinolone cream 0.1%) or oral steroids, Burow’s solution (aluminum acetate)
PUVA Phototherapy

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13
Q

what are common secondary infections of diaper dermatitis?

A

Satellite lesions ⇒ candidiasis
Impetigo (s. aureus)
Herpes simplex virus (child sexual abuse)

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14
Q

what is spared in perioral dermatitis?

A

the lop margin (vermillion border)

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15
Q

what is the treatment for perioral dermatitis? what should be avoided?

A

Topical metronidazole, avoid steroids

Mild: topical ALONE 1st line
Topical Pimecrolimus 0.1%

Erythromycin solution q12h

Metronidazole 0.75% gel q12h

Clindamycin lotion q12 hours

Oral ABX: Doxycycline if necessary - no gels, solutions, or lotions on eye

Moderate: topical + oral ABX

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16
Q

what is the most common cause of erythema multiforme?

A

herpes simplex

other causes: mycoplasma pneumonia, URI, drugs are less comon

17
Q

how does erythema multiform present? how is it different than urticaria, SJS/TEN?

A

Presents as raised (papular), target lesions with multiple rings and dusky center (as opposed to annular lesions in urticaria)
Negative Nikolsky sign (as opposed to SJS/TEN)

18
Q

Erythema infectiosum (fifth disease)

A

Parvovirus B19 - “slapped cheek” rash on face - lacy reticular rash on extremities, spares palms, and soles

Resolves in 2-3 weeks

Treatment is supportive, anti-inflammatories

19
Q

what may parvovirus cause in patients with sickle cell and G6PD?

A

aplastic crisis (normocytic-normochromic anemia)

20
Q

Hand-foot-and-mouth disease

A

Children < 10 years old caused by coxsackievirus type A virus producing sores in the mouth and a rash on the hands, feet, mouth, and buttocks

The virus usually clears up on its own within 10 days

Treatment is supportive, anti-inflammatories

21
Q

Measles (Rubeola)

A

The 4 C’s - cough, coryza, conjunctivitis, and cephalocaudal spread (head down)

Morbilliform - maculopapular, brick red rash on face beginning at hairline then progressing to palms and soles last - rash lasts 7 days

Koplik spots (small red spots in buccal mucosa with blue-white pale center) precedes rash by 24-48 hours.

Treatment is supportive - anti-inflammatories, isolate for 1 week after onset of rash. MMR vaccine (12-15mo, 4-6yr)

22
Q

Rubella (German measles)

A

**“3-day rash” ** pink light-red spotted maculopapular rash first appears on the face, spreads caudally to the trunk and extremities, and becomes generalized within 24 hours (lasts 3 days)

Cephalocaudal spread of maculopapular rash, lymphadenopathy (posterior cervical, posterior auricular)
Although the distribution of the rubella rash is similar to that of rubeola, the spread is much more rapid, and the rash does not darken or coalesce
*Nagayama spots *

Teratogenic in 1’st trimester - congenital syndrome - deafness, cataracts, TTP, mental retardation

Treatment consists of supportive care. MMR vaccine (12-15mo, 4-6yr)

23
Q

which xanthem is teterogenic in the first trimester?

A

Rubella - congenital syndrome - deafness, cataracts, TTP, mental retardation

24
Q

Roseola (sixth disease)

A

**Herpesvirus 6 or 7,
**
only childhood exanthem that starts on the trunk and spreads to the face

High fever 3-5 days then rose pink maculopapular blanchable rash on trunk/back and face;

Treatment is supportive and in most cases, roseola is a benign and self-limited disease

Fever can be controlled with antipyretics (eg, acetaminophen) if it is associated with discomfort

The rash resolves without treatment

25
MCC of impetigo?
S. aureus
26
tx of impetigo
1st line: topical Bactroban (**mupirocin**) x 5 days Widespread infection: Cephalexin or Erythromycin x 1 wk MRSA: Doxycycline Sick + MRSA: Vancomycin Bullous or severe: PO ABX
27
Lice (pediculosis) tx
launder potential fomites such as sheets in hot water (> 131 F or 55 C) **Permethrin topical** is the drug of choice: Capitis: permethrin shampoo x 10 minutes; Pubis: permethrin lotion x 8 hours
28
What is lichen planus? What is it characterized by?
Lichen planus (LP) is a chronic papulosquamous inflammatory dermatosis of unknown etiology, probably autoimmune in origin Clinically characterized by 5 Ps ⇒ **purple, papule, polygonal, pruritus, planar**
29
What skin condition is characterized by an initial herald patch, followed by the development of a diffuse papulosquamous rash (x-mas tree like pattern)?
Pityriasis rosea
30
What is the tx for pityriasis rosea?
The disease is self-limiting: topical or systemic steroids and antihistamines are often used to relieve itching. Asymptomatic lesions do not require treatment
31
The presentation of Pruritic papules - S-shaped or linear burrows on the skin. Often located in web spaces of hands, wrists, and waist with severe itching (worse at night) is most consistent with?
Scabies
32
dx and tx of scabies
dx: microscopic obs of skin scraping tx: topical permethrin 5% Sulfur 5%-10% ointment (< 2 months old) All clothing, bedding, and towels are washed and dried using heat and have no contact with the body for at least 72 hours Oral ivermectin if extensive involvement or immunocompromised individual *Do not use in pregnant/breastfeeding women or in children < 15 kg* Pruritus may persist for 2-4 weeks after treatment
33
body distribution of TEN vs SJS
SJS - 3-10% TEN - >30%