Peds exam 3 Flashcards
First signs of hematologic disorder or cancer in children?
Skin color changes such as pallor, bruising, and flushing are often the first signs that a problem is developing
-change in mental status (lethargy) can indicate low hemoglobin levels
Physical examination of the child with a hematologic or neoplastic disorder includes what?
inspection and observation
palpation
auscultation
general appearance and observation of child with disorder of altered cellular regulation
-thin, frail appearance
-asymmetry of body parts
-altered consciousness
-child’s response to stimuli
-bleeding gums or pale mucous membranes
-assess for rectal bleeding or vaginal discharge
-pallor in nail beds, palms, and soles
-clubbing of fingers
-assess urinary output
-assess vital signs
-assess conjunctiva
Auscultation for children with altered cellular regulation
assess for any adventitious breath sounds or heart murmurs
-assess rate, rhythms, tone
-listen to bowel sounds
Palpation with altered cellular regulation disorders
Measure BP (may change with alterations in blood volume)
Measure peripheral pulses
Assess capillary refill (may be prolonged)
Palpate lymph nodes
Palpate abdomen for splenomegaly, hepatomegaly, tenderness
Assess for swelling in any parts of the body
Assess skin temp
Assess skin elasticity (turgor)
Assess if joints are tender and if ROM is limited
Common medical treatments for cancer and altered cellular regulation disorders
Blood transfusion
Leukapheresis- Removal of the blood to collect specific blood cells. The remaining blood is returned to the body.
Hematopoietic stem cell transplantation
Supplemental oxygen
Biopsy
Splenectomy
surgical removal of tumor
Radiation
Central venous catheter
Implanted port
Benefit to acupuncture
may help to decrease nausea, vomiting, and aversion to chemotherapy.
Adverse effects of radiation therapy vs chemotherapy
radiation therapy:
include
-FATIGUE,
-nausea, vomiting,
-oral mucositis,
-myelosuppression- A condition in which bone marrow activity is decreased, resulting in fewer red blood cells, white blood cells, and platelets., and
-ALTERATIONS OF SKIN INTEGRITY at the site of irradiation
chemotherapy:
-immunosuppression –>infection, myelosuppression,
-nausea, vomiting,
-CONSTIPATION,
-oral mucositis,
-ALOPECIA, and
-PAIN
Hemopoietic stem cell transplant indications
(cases when performed)
leukemias, lymphomas, sickle cell disease, aplastic anemia, thalassemia
hemopoietic stem cell transplant considerations (what to maintain, provide, avoid)
Maintain medical asepsis and isolation (prevents infection)
Provide good oral care
Avoid rectal temps or suppositories
indications for radiation therapy (4)
before or after surgical resection
leukemia
lymphoma
solid tumors
a-fetoprotein (AFP)
-where produced
-decreased levels by what age
-elevated in what cases
-determines what
produced by fetal liver and yolk sac
decreases to very low levels by age one
-usually elevated in Hodgkin disease and other cancers
-determines tumor burden
Urine catecholamines (VMA, HVA)
-diagnosis for what
-involves what?
-levels altered by what?
catabolism of catecholamines causes elevated levels in the urine
-Diagnosis of neuroblastoma
-involves 24-hour urine collection
-levels may be altered with certain foods and vigorous exercise
MRI in evaluating cancer
can identify extent of tumor or metastatic spread
CT in evaluating cancer
can identify location of tumor or metastasis
Ultrasound in evaluating cancer
identify tumor presence, especially in abdomen or kidney
Bone marrow aspiration and biopsy
evaluation for leukemia or metastasis of other cancers in bone marrow
Bone scan
identifies metastasis of bone
chest x-ray use
identifies tumor or metastasis in the thorax
*x-ray is mainly used to monitor cancer
Anemia
is a condition in which the level of RBCs is lower than the age-appropriate normal value. Anemia may develop as a result of decreased production of RBCs or loss and destruction of RBCs.
What can cause anemia?
related to lack of dietary intake of the nutrients needed to produce the cells, alterations in the cell structure, or malfunctioning tissues (e.g., bone marrow), toxin exposure, medication, trauma
Anemias related to nutritional deficiency
-may be related to what?
iron deficiency,
folic acid deficiency, and
pernicious anemia
-maybe related to food dislikes or malabsorption issues
Anemia related to toxin exposure
example is lead poisoning
Hemolytic anemia
Anemia caused by the alteration or destruction of the RBCs