peds nephro Flashcards
(29 cards)
a mutation in the nephrin gene that causes nephrotic syndrome in the first year of life is
congenital NS of the Finnish type
Congenital NS of the finnish type is characterized by
Thrombosis and malnutrition
minimal change disease is usually associated with NS in children when?
after the first year of life
14 month old presenting with generalized edema, what can this be?
minimal change
in young children:
who gets more Minimal change disease
Males 3:2
what features suggest you are dealing with something other than Minimal change disease nephrotic syndrome
age 12
Initial treatment of minimal change disease includes
Prednisone over 3-4 months
control of edema
low salt
minimal change disease DOES NOT LEAD TO
chronic kidney disease
Steroid resistant nephrotic syndrome iS NOT
minimal change disease
long term remission from minimal change disease happens
after puberty
If urine is tea-colored think
nephritic syndrome
urine microscopy findings in nephritic syndrome
RBC and RBC casts
most common primary renal disease associated with hypocomplementemic GN
post infectious - post strep GN
most common systemic disease associated with hypocomplementemic GN
SLE
most common primary renal disease associated with normocomplementemic C3
IgA nephropathy
ANCA + pauci
most common systemic disease associated with normocomplementemic C3
ANCA+ disease
anti GBM
Henoch Schonlein purpura
Low C3
Nephritic syndrome
evidence of previous infection suggests
Post-infectious GN
when does post strep GN occur
10-14 days after a strep pharyngitis infection
up to 3 weeks after impetigo infection
how do you NOT treat post-infectious GN
steroids! dont give,
give diuretics, antihypertensives
how long for the C3 to be back to normal in post-infectious GN
6-8 wks
classic triad of HUS
MAHA
Thrombocytopenia
Acute kidney Injury
Main cause of acute kidney injury in children
HUS
typical or diarrhea positive HUS is caused by
Shiga toxin producing E coli
over 90% of cases
classic blood film features in HUS
shistocytes
