Peer 8 - systemic infectious disorders

Question 1

dx of amebiasis?

Answer 1

stool examination for cysts, antigen tests on stool, or serum serology

Question 2

tx of amebiasis?

Answer 2

metronidazole + iodoquinol or paromomycin

Question 3

defn of toxic shock syndrome?

Answer 3

fever, diffuse macular erythroderma, desquamation, hypotension, and

• vomiting/diarrhea, renal failure, elevated transaminases, thrombocytopenia, AMS

Question 4

adult with previous tetanus shot needs what if presents with laceration/open wound?

Answer 4

tdap

Question 5

tx of clostridial myonecrosis?

Answer 5

can be monotherapy:

imipenem-cilastatin, meropenem, ertapenem, zosyn

Question 6

cause of clostridial myonecrosis?

Answer 6

post surgical or traumatic wounds, affects already infected or traumatized tissue

Question 7

chickenpox rash?

Answer 7

vesicular eruption primarily on trunk with lesions in various stages of development?

Question 8

smallpox rash?

Answer 8

synchronized vesicular eruption with highest concentration on face and limbs

Question 9

sx of histoplasma?

Answer 9

erythema nodosum (painful red nodules on surfaces of anterior lower leg), pneumonia, and headache

Question 10

definitive diagnosis of malaria?

Answer 10

blood smear

Question 11

sx of malaria?

Answer 11

high fever, ill appearance, tachypnea, and tachycarida

Question 12

tx of toxoplasmosis in AIDS patient with ring enhancing lesions?

Answer 12

pyrimethamine, and sulfadiazine plus folinic acid

Question 13

sx of ehrlichiosis?

Answer 13

myalgias, malaise, headache, nausea, vomiting, anorexia, abd pain

• labs show leukopenia, thrombocytopenia, liver enzymes

Question 14

late stage complications of lyme disease?

Answer 14

fever, adenopathy, annular lesions, bilateral facial palsy, cardiac abnormalities

• tertiary - chronic arthritis, myocarditis, subacute encephalopathy, axonal polyneuropathy

Question 15

tx of choice for rocky mountain spotted fever?

Answer 15

doxy 100 mg BID for 7-10 days

Question 16

side effect of efavirenz?

Answer 16

psychosis and depression

Question 17

side effect of nevirapine?

Answer 17

hepatic failure

Question 18

side effect of ritonavir?

Answer 18

metabolic syndrome and hyperlipidemia

Question 19

side effect of indinavir?

Answer 19

nephrolithiasis

Question 20

side effect of zidovudine, didanosine, lamivudine

Answer 20

lactic acidosis

azt - bone marrow suppression, macro anemia

Question 21

roseola sx?

Answer 21

high spiking fevers, then nondescript rash

Question 22

rubella sx?

Answer 22

rash moves head to toe with fever, and soft palate findings

Question 23

measles sx?

Answer 23

koplik spots and rash spreads head to toe with confluence

Question 24

tx of rocky mountain spotted fever in pediatric patients?

Answer 24

doxy

Question 25

sx of rocky mountain spotted fever?

Answer 25

fever, myalgias, HA, abd pain, macular rash from extremities to torso

Question 26

diagnostic test of choice for giardiasis?

Answer 26

stool antigen

Question 27

tx of PCP (PNA)?

Answer 27

bactrim 21 days

Question 28

tx of severe PCP? defn of severe PCP?

Answer 28

steroids Pao2 less than 70, A-a gradient of 35 or more, oxygen saturation less than 92% on room air