Pelvic Mass Flashcards

(42 cards)

1
Q

what are some non-gynaecological causes of a pelvic mass

A

Constipation
Caecal carcinoma
Appendic abscess
Diverticular abscess

urinary retention
pelvic kidney

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2
Q

where can gynaecological pelvic masses come from

A

Uterus - body, cervix
Tubal (and para tubal)
Ovary

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3
Q

what are the causes of uterine pelvic mass

A

Fibroids
Pregnancy
Endometrial cancer (however usually presents early so pelvic mass unlikely)
Cervical cancer

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4
Q

what are uterine fibroids

A

Leiomyomas (benign smooth muscle tumours)

v common esp >40 years

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5
Q

what are the different types of fibroids

A
pedunculate - protrudes outside the muscle 
intracavitary - inside the uterus 
intramural - middle of muscle wall
submucous -bulge into cavity 
subserous - under the serosa
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6
Q

how do uterine fibroids present

A
asymptomatic/incidental finding 
menorrhagia (V heavy periods) 
pelvic mass 
pain/tenderness
'pressure' symptoms
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7
Q

how do you investigate fibroids

A

Hb if heavy bleeding
US usually diagnostic
MRI for more precise localisation

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8
Q

how do you treat fibroids

A

expectant (leave it alone)
traditional hysterectomy if family complete

myomectomy
uterine artery embolisation
hysteropoc resection

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9
Q

what are causes of tubal swellings

A

Ectopic pregnancy
Hydrosalpinx (tube filled with fluid)
Pyosalpinx (tube filled with puss)
Paratubal cysts

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10
Q

causes of ovarian masses

A

tumours/neoplasm
-benign or malignant

non-tumours

  • functional cysts
  • endometriotic cysts (endometriosis on the ovary)
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11
Q

what is a functional cyst

A

cyst related to ovulation

  • follicular cysts
  • luteal cysts

usually resolve spontaneously
asymptomatic/incidental finding (my be mistral disturbance, bleeding, rupture and pain)

expectant management appropriate

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12
Q

what is an endometriotic cyst

A

endometriosis (endometrium in wrong place) causes endometrial deposits on the ovary

can cause blood filled cysts on ovaries (chocolate cysts)

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13
Q

how do endometriosic cysts present

A

severe dysmenorrhoea and premenstrual pain
dyspareunia (painful sex)
subfertility
tender mass with ‘nodularity’ and tenderness behind uterus
occasionally asymptomatic until large chocolate cyst which ruptures

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14
Q

where can primary ovarian tumours arise from

A

Surface epithelium
Germ Cells
Stroma

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15
Q

what primary ovarian tumours arise from the surface epithelium

A
serous 
mucinous 
endometrioid 
clear cell 
Brenner
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16
Q

what primary ovarian tumours arise from germ cells

A

benign cystic teratoma (dermoid cyst)

malignant germ cell tumours (v rare)

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17
Q

what primary ovarian tumours arise from stroma

A

fibroma
if theca/leydig cell it secretes androgens
if granuloma cell it secretes oestrogen

18
Q

what do malignant germ cell tumours produce

A

HCG causing false positive pregnancy test of AFP

19
Q

what do dermoid cysts produce

A

totipotential

produce teeth, sebaceous material, hair

thyroid tissue - thyrotoxicosis

20
Q

what do granuloma cell tumours produce

A

oestrogen

leads to precocious puberty, post menopausal bleeding

21
Q

what syndrome are fibromas related to

A

Meig’s syndrome - benign fibroma with pleural effusion and ascites

22
Q

where do secondary (metastatic). ovarian tumours most commonly come from

A

breast
pancreas
stomach
GI primaries

23
Q

how does ovarian cancer usually present

A

mass, swelling or pressure symptoms

early transperitoneal spread - deposits on all peritoneal surfaces

malignant ascites with protein exudate

more insidious symptoms

bloating 
heart burn 
weight loss 
'pressure' symptoms eg. bladder change of bowel habit 
SOB/pleural effusion 
leg oedema or DVT
24
Q

what genes can predispose to ovarian cancer

A

BRACA 1 & 2 (breast and ovarian)

HNPCC (Lynch syndrome- bowel, endometrial, ovarian and others)

25
what are some risk factors for ovarian cancer
increasing age nulliparity family history (OCP is a protective factor)
26
how do you investigate a suspected ovarian cancer
history and exam tumour markers USS - better for imagineer nature of cyst CT - good for assessing disease outwit ovarian
27
what tumour markers are measured in ovarian cancer
CA 125 | Carcino-embryonic antigen (CEA )
28
when is CA125 raised
in 80% of ovarian cancers normal level does not exclude cancer
29
what things can cause a moderate raise in CA125
``` endometriosis peritonitis/infection pregnancy pancreatitis ascites other malignancies ```
30
when is CEA (carcinoma-embryonic antigen) raised
moderately raised in ovarian cancer especially in mucinous tumours
31
what is the main function of CEA tumour marker
excluded mets from GI tumour
32
how does ovarian cancer present on ultrasound scan
complex mass with solid cystic area multi-lobulated thick separations associated ascites bilateral disease
33
how do you calculate the risk of malignancy index for ovarian cancer and what do you do if its high
combine menopausal status with serum CA125 and US score if elevated refer to gynaecological cancer team
34
how do you treat benign ovarian cysts
removal or drainage if benign
35
how do you treat malignant ovarian cysts
delbuluking surgery (removal of ovaries and uterus with removal/biopsy of momentum) examination of all peritoneal surfaces chemotherapy given pre-srugery unlikely to cure
36
what symptoms to ask in a pelvic mass history
``` slow/fast growing pain pressure symptoms menstrual history bloating parity and fertility problems family history previous gynae history ovarian cancer symptoms ```
37
how do you describe a pelvic mass
``` size (cms or weeks gestation) consistency (soft, firm, craggy) surface (smooth, irregular) tenderness mobility relation to uterus pouch of Douglas ```
38
what investigations are done for a pelvic mass
``` Hb WCC/CRP Biochem esp serum albumin Tumour markers (CA125, CEA) USS MRI for fibroids/uterine mass CT for suspected ovarian Ca CT/US guided tissue biopsy ```
39
treatment option of endometriomas (endometrial cyst on ovary)
GnRH analogues Oral contraceptive pill if not surgery
40
what is Meig's syndrome
Benign ovarian fibroma associated with ascites +/- pleural effusion
41
Treatment for germ cell tumours
fertility sparing treatment | unilateral salpingoophrectomy +/- chemotherapy
42
treatment options for endometrial fibroids
conservative medical -GnRH analogues, mirena coil, progestins surgical -lapparoscopic myomectomy, subtotal hysterectomy or total hystorectomy