Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Classic Lit Fall 2021 > Periodontal Wound Healing > Flashcards

Periodontal Wound Healing Flashcards

(51 cards)

Start Studying
1
Q

What classical study looked at healing of Epi and CT?

A

Engler et al. 1966
Ramfjord et al. 1966

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What happens in Epi and CT in the first 2 hrs?

A

Blood clot formation

PMN migrate to both sites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What happens in Epi and CT in the first 9hrs?

A

Continued PMN migration and formation of poly-band between blood clot and spinous layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What happens in Epi and CT from 9-13hrs?

A

Epithelial cell migration and DNA Synthesis

CT continued PMN migration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

When does angiogenesis occur in the CT?

A

12-24hrs (Ramfjord 1966) During this time there is also CT proliferation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What happens from days 1-2 in EPI and CT?

A

Epithelial DNA synthesis

CT Angiogenesis + proliferation continues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What happens from days 2-5 and 5-7?

A

Epithelial cell migration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

When does the sulcus form?

A

5-7days healing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What happens from 7-14days?

A

New keratinized marginal gingiva (Epi)

New FGM formed due to CT proliferation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

When is the peak of osteoclastic activity during periodontal surgical healing?

A

7-14 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

When does CT mature after periodontal surgery?

A

4-6weeks

Epithelialization of marginal gingiva and sulcus is complete - CT is organized

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the phases of wound healing?

A

Hemostasis

Inflammation

Proliferation

Matrix Formation/Remodeling/Maturation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What happens during the Hemostasis phase?

A

Blood vessel injury > cellular leakage (leukocytes/erythrocytes/plasma cells) > vasoconstriction > platelet aggregation and coagulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the role of a blood clot in healing?

A

Protects denuded tissues

serves as a provisional matrix for cell migration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What happens during the inflammation phase?

A

Wound Cleaning takes place

Neutrophils remove debris and bacteria > Monocytes convert to macrophages > Macrophages and Fibroblasts phagocytose remaining debris and bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What happens during the proliferation phase of healing?

A

Granulation tissue formation

Macrophage release growth factors (induce granulation tissue formation, and fibroblast migration/proliferation) > keratinocytes migrate to form basal cells (epidermal migration begins) > Collagen formation starts > Endothelial cells create a vascular system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What happens during the matrix formation/remodeling/maturation phase?

A

New collagen rich matrix produced by fibroblasts > wound contraction > wound maturation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

How long does wound maturation take?

A

6 weeks to 1 year

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Which phase determines if regeneration or repair will occur?

A

Matrix formation/remodeling/maturation phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What characteristics of the oral cavity complicate wound healing in comparison to the rest of the body?

A

Residual calculus

Rigid - nonvascular tooth surface attached to CT and Epi (vs 2 opposing vascular tissues)

PDL resources

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

How does healing of periodontium to tooth occur?

Study These Flashcards
A

Wikesjo et al. 1991

attachment to dentin surfaces is mediated by adsorption of plasma proteins to the surface and subsequent development and maturation of a fibrin clot.

22
Q

What kind of animal was used for the Engler and Ramfjord 1966 study?

Study These Flashcards
A

Rhesus Monkeys

23
Q

What kind of healing occurs after SRP? Citation?

Study These Flashcards
A

Long Junctional Epithelium

Caton & Zander 1979

24
Q

Is LJE Better, Equal, or Less protective than JE?

Study These Flashcards
A

Equal

Magnusson et al. 1983

25
What kind of healing occurs after MWF? Citation?
LJE Caton et al. 1980
26
What are the phases of healing for osseous surger?
Inflammatory Phase Reparative Phase Remodeling Phase
27
What happens during the Inflammatory phase of osseous healing? How long is it?
2weeks long Blood clot formation Cytokines recruit inflammatory cells to the wound area
28
What happens during the Reparative phase of osseous healing?
Immature new bone matrix and cartilage scaffolding occurs Scaffold mineralizes over a period of 6-12 weeks forming immature woven bone
29
What happens during the Remodeling phase of osseous healing?
Lamellar bone replaces woven bone
30
How much bone loss can you expect after osseous surgery?
Wilderman et al. 1979 6 months: 1.2mm bone resorption Following 12 months: 0.4mm bone apposition Net bone loss: 0.8mm
31
Selipsky 1976
The initial bone loss and later bone apposition after osseous surgery explains why there is initial increased mobility, followed by return to pre-surgical status/
32
What is the average bone loss following osseous in the interradicular space?
0.23mm Moghaddas and Stahl 1980
33
What is the average bone loss following osseous in the Radicular area?
0.55mm Moghaddas & Stahl 1980
34
What is the average bone loss following osseous in the Furcation? Citation
0.88mm Moghaddas & Stahl 1980
35
What reasons are there for Crown Lengthening procedures?
Biologic Width invasion Altered passive eruption Subgingival caries
36
How long should we wait after CL to place crowns? (non-esthetic zone)
Lanning et al. Heals to ~3mm above osseous crest after 3mo with minimal changes in vertical position of the FGM from 3-6mo
37
How long should we wait after CL to place crowns? (esthetic zone)
Brägger et al. 6mo after healing there is minimal change in the FGM
38
Schropp et al. 2003
50% width reduction after the first 3mo following extraction
39
Evian et al. 1982
Optimal time to harvest graft from socket 8-12weeks peak in osteogenic activity
40
What is the sequence of socket healing?
Amler & Salman 1960 1. Blood clot fills socket 2. Granulation tissue replaces (2-3days) 1. Young CT replaces (by 20days) 3. Uncalcified Bone Formation 4. Filling in socket with primary bone 5. Loss of Lamina Dura 6. Bone density similar to surrounding alveolar bone
41
What are the phases of FGG healing?
Oliver et al. 1968 3 phases Initial (0-3 days) Revascularization (4-11 days) Tissue Maturation (11-42 days)
42
What happens during the Initial phase of FGG healing?
(Oliver et al. 1968) 0-3 days CT Exudate accumulates between collagen fibers = Plasmatic Circulation providing cell nutrition Epi Degeneration with desquamation of outer layer Blood supply None
43
What happens during the Revascularization phase of FGG healing?
(Oliver et al. 1968) 4-11 days CT Dense fibrous union btw graft/periostium New FGM Epi Degeneration + Desquamation of entire graft epi Epi proliferation from adjacent tissues Blood supply Capillary budding along base of graft
44
What happens during the Tissue Maturation phase of FGG Healing?
(Oliver et al. 1968) 11-42 days CT Increased Density Epi Increased Thickness Keratinization occurs at day 28 Blood supply Reduction in vascularity
45
When does keratinization of FGG occur?
28 days Oliver et al. 1968
46
How much creeping attachment can be expected form FGG?
0.89mm on average from 3-12mo Matter & Simasoni
47
How does CTG healing occur?
Guiha 7days - vascularization from periodontal plexus and supra-periosteal plexus 14days - complete graft vascularization 28 days - JE formed 28-60 days - Normal vascularization/oral epi
48
How much CTG can be exposed?
Up to 30% Guiha et al. 2001
49
Bone loss after full vs partial thickness flap
Wood et al. 1972 Partial: 0.98mm Full: 0.62mm Fickl et al. 2011 Partial: 0.12mm Full: 0.64mm
50
Benefits of microsurgery for healing?
Higher vascular perfusion less trauma and vessel injury enhanced root coverage enhanced wound healing Burkhardt & Lang 2005
51
What are the major systemic factors that can effect wound healing?
Smoking and uncontrolled Diabetes

Classic Lit Fall 2021 (29 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions