PERIPHERAL GIANT CELL GRANULOMA

Question 1

CONCEPT

Answer 1

WELL-DEFINED FIRM GROWTH

Question 2

ORALLY CLINICALLY

Answer 2

MANDIBLE BETWEEN FIRST MOLARS AND INCISOR

Question 3

INCIDENCE

Answer 3

GINGIVA OR EDENTULOUS ALVEOLAR RIDGE

Question 4

CHARACTERISTICS

Answer 4

-BASE SESSILE/SURFACE SMOOTH OR SLIGHTLY GRANULAR/COLOR VARIES FROM PINK TO DARK RED-BLUISH PURPLE
- REACTIVE LESION ASSOCIATED WITH TRAUMA/IRRITATION HISTORY
- LESION AGRESSIVE: RESORBS BONE UNDER GINGIVA (“CUP SHAPED” RADIOLUCENCY)

Question 5

DIFERENTIAL DIAGNOSIS

Answer 5

INDISTINGUISHABLE FROM PYOGENIC GRANULOMA

Question 6

HISTOLOGICALLY

Answer 6

• FIBROBLASTS/MULTINUCLEATED GIANT CELLS IN A STROMA CONTAINING COLLAGEN
• MULTINUCLEATED GIANT CELLS ARE PRESENTIN PERIPHERAL GIANT CELL GRANULOMA, CENTRAL GIANT CELL GRANULOMA, HYPERPARATHYROIDISM, LANGERHANS CELL HISTIOCYTOSIS, CHERUBISM, ANEURYSMAL BONE CYST

Question 7

TREATMENT

Answer 7

CONSERVATIVE EXCISION/CURETTAGE OF THE UNDERLYING BONE

Question 8

RECURRENCE

Answer 8

10-18% / RE-EXCISION